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- W2009451633 abstract "Endotracheal suctioning of mechanically ventilated, newborn infants is accompanied with slight hypoxia and changes in arterial blood pressure. These events may have adverse effects on the cerebral haemodynamics of the sick neonate. 30 newborn infants were investigated twice during endotracheal suctioning which was performed with and without preoxygenation (GA 25-41 weeks). Brain oxygenation was estimated by near infrared spectroscopy, and mean arterial blood pressure (MABP). arterial blood gases (PO2 and PCO2 ) and arterial blood oxygen saturation (SaO2) were recorded simultaneously. In the brain, oxygenated hemoglobin and oxidized cytochrome aa3 decreased slightly during the procedures, as expected (P<0.05). The changes of total cerebral blood content (CBVI) were closely related to the concomitant changes of PCO2 (P<0.0001). whereas there was no relation between changes of CBVI and changes of PO2. SaO2 or MABP. respectively. A 10 min period of preoxygenation did not ameliorate the physiologic responses. The findings were independent of the gestational age and indicate an intact cerebral autoregulation of the newborn infant." @default.
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- W2009451633 date "1990-09-01" @default.
- W2009451633 modified "2023-09-27" @default.
- W2009451633 title "18 The effect of endotracheal suctioning on the cerebral oxygenation of newborn infants" @default.
- W2009451633 doi "https://doi.org/10.1203/00006450-199009000-00042" @default.
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