FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009453058> ?p ?o ?g. }

• W2009453058 endingPage "1947" @default.
• W2009453058 startingPage "1932" @default.
• W2009453058 abstract "Abstract We report the synthesis of new persulfide-spacer N-substituted-2-azetidinone-D-glucosamine in an attempt to potentially provide new antibiotics. The Schiff base ligands considered for this study were derived from D-glucosamine and 2-hydroxybenzaldehyde, 4-methoxy-benzaldehyde, cinnamaldehyde, 4-chlorobenzaldehyde, and 4-hydroxy-3-methoxy-benzaldehyde. Staudinger [2+2] cycloaddition of benzyloxyacetyl chloride to the newly reported per-O-allyl-N-substituted benzylidene-2-deoxy-β-D-glucosamine provided the sugar-based monocyclic β-lactams in moderate yields. Radical addition of 2-mercaptoethanol catalyzed by azobisisobutyronitrile to the per-O-allyl-N-substituted-2-azetidinone-D-glucosamine led to the corresponding persulfide-spacers in good yields. All new compounds were characterized by spectroscopic and spectrometric methods. The scanning electron microscopy image of 1,3,4,6-tetra-O-[3-(hydroxythioethyl)-propyl]-2-deoxy-2-N-[(3-benzyloxy-4-(4-chloropenyl)-2-azetidinone]-β-D-glucopyranoside, as a representative example, demonstrated a super hydrophobic layer formed via highly organized thioether spacers on gold as the adsorbate system through the formation of sulfur–gold bonds. The reported glucosides showed a moderate antifungal activity against Candida albicans while being slightly to moderately active against gram-positive and gram-negative bacteria used in this investigation at a concentration of 1 mg/mL dissolved in dimethyl sulfoxide. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file. GRAPHICAL ABSTRACT" @default.
• W2009453058 created "2016-06-24" @default.
• W2009453058 creator A5015939787 @default.
• W2009453058 creator A5063328075 @default.
• W2009453058 date "2011-08-24" @default.
• W2009453058 modified "2023-09-27" @default.
• W2009453058 title "Synthesis and Antimicrobial Activity of Novel 3-Benzyloxy-4-Substituted-2- Azetidinones: Formation of a Hydrophobic Layer Via a Self-Organization Effect" @default.
• W2009453058 cites W1966731869 @default.
• W2009453058 cites W1973912200 @default.
• W2009453058 cites W1985702957 @default.
• W2009453058 cites W1989823651 @default.
• W2009453058 cites W1990098432 @default.
• W2009453058 cites W1993283556 @default.
• W2009453058 cites W1997106739 @default.
• W2009453058 cites W2002770836 @default.
• W2009453058 cites W2004037393 @default.
• W2009453058 cites W2004779492 @default.
• W2009453058 cites W2006033950 @default.
• W2009453058 cites W2007071156 @default.
• W2009453058 cites W2009258176 @default.
• W2009453058 cites W2011616004 @default.
• W2009453058 cites W2019658508 @default.
• W2009453058 cites W2029118481 @default.
• W2009453058 cites W2029146183 @default.
• W2009453058 cites W2031514228 @default.
• W2009453058 cites W2031838800 @default.
• W2009453058 cites W2032519798 @default.
• W2009453058 cites W2033814619 @default.
• W2009453058 cites W2034284481 @default.
• W2009453058 cites W2035577388 @default.
• W2009453058 cites W2038887383 @default.
• W2009453058 cites W2040763963 @default.
• W2009453058 cites W2044385927 @default.
• W2009453058 cites W2054292263 @default.
• W2009453058 cites W2055800251 @default.
• W2009453058 cites W2062194296 @default.
• W2009453058 cites W2062284931 @default.
• W2009453058 cites W2069350605 @default.
• W2009453058 cites W2070850964 @default.
• W2009453058 cites W2077062110 @default.
• W2009453058 cites W2078448254 @default.
• W2009453058 cites W2088229138 @default.
• W2009453058 cites W2088235808 @default.
• W2009453058 cites W2088272088 @default.
• W2009453058 cites W2102283478 @default.
• W2009453058 cites W2105202307 @default.
• W2009453058 cites W2143266713 @default.
• W2009453058 cites W2149482213 @default.
• W2009453058 cites W2154873102 @default.
• W2009453058 cites W2158620829 @default.
• W2009453058 cites W2161195329 @default.
• W2009453058 cites W2166806803 @default.
• W2009453058 cites W2491694817 @default.
• W2009453058 cites W2949974066 @default.
• W2009453058 cites W2950040498 @default.
• W2009453058 cites W4248860448 @default.
• W2009453058 cites W60307892 @default.
• W2009453058 doi "https://doi.org/10.1080/10426507.2011.553208" @default.
• W2009453058 hasPublicationYear "2011" @default.
• W2009453058 type Work @default.
• W2009453058 sameAs 2009453058 @default.
• W2009453058 citedByCount "1" @default.
• W2009453058 countsByYear W20094530582017 @default.
• W2009453058 crossrefType "journal-article" @default.
• W2009453058 hasAuthorship W2009453058A5015939787 @default.
• W2009453058 hasAuthorship W2009453058A5063328075 @default.
• W2009453058 hasConcept C155647269 @default.
• W2009453058 hasConcept C161790260 @default.
• W2009453058 hasConcept C178790620 @default.
• W2009453058 hasConcept C185592680 @default.
• W2009453058 hasConcept C188027245 @default.
• W2009453058 hasConcept C2778125326 @default.
• W2009453058 hasConcept C2779444094 @default.
• W2009453058 hasConcept C2779692420 @default.
• W2009453058 hasConcept C2780104969 @default.
• W2009453058 hasConcept C523546767 @default.
• W2009453058 hasConcept C54355233 @default.
• W2009453058 hasConcept C71240020 @default.
• W2009453058 hasConcept C86803240 @default.
• W2009453058 hasConceptScore W2009453058C155647269 @default.
• W2009453058 hasConceptScore W2009453058C161790260 @default.
• W2009453058 hasConceptScore W2009453058C178790620 @default.
• W2009453058 hasConceptScore W2009453058C185592680 @default.
• W2009453058 hasConceptScore W2009453058C188027245 @default.
• W2009453058 hasConceptScore W2009453058C2778125326 @default.
• W2009453058 hasConceptScore W2009453058C2779444094 @default.
• W2009453058 hasConceptScore W2009453058C2779692420 @default.
• W2009453058 hasConceptScore W2009453058C2780104969 @default.
• W2009453058 hasConceptScore W2009453058C523546767 @default.
• W2009453058 hasConceptScore W2009453058C54355233 @default.
• W2009453058 hasConceptScore W2009453058C71240020 @default.
• W2009453058 hasConceptScore W2009453058C86803240 @default.
• W2009453058 hasIssue "9" @default.
• W2009453058 hasLocation W20094530581 @default.
• W2009453058 hasOpenAccess W2009453058 @default.
• W2009453058 hasPrimaryLocation W20094530581 @default.
• W2009453058 hasRelatedWork W1492047339 @default.
• W2009453058 hasRelatedWork W1984502979 @default.

• next