FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009461982> ?p ?o ?g. }

• W2009461982 endingPage "215" @default.
• W2009461982 startingPage "209" @default.
• W2009461982 abstract "Ten healthy subjects (four male) of mean age 31 years (range 25-40) took part in a randomized double-blind four-way crossover study to examine the cognitive and psychomotor effects of repeated oral doses of dextropropoxyphene and morphine. Four treatments were compared: dextropropoxyphene napsylate 100 mg, morphine sulphate 10 mg, lorazepam 0.5 mg and placebo. Four doses of each drug were given at 4-h intervals to each subject on four separate study days at least 1 week apart. Cognitive function was assessed using choice reaction time, number vigilance, memory scanning, immediate and delayed word recall, word recognition, picture recognition, critical flicker fusion threshold (CFFT) and subjective measures of alertness, calmness and contentment. Lorazepam impaired the speed of responding on all tasks in which speed was recorded (except digit vigilance) and increased subjective ratings of calmness. Morphine had one major effect, which was to increase the accuracy of responding on the choice reaction time task, at every assessment. Morphine produced some sporadic effects in other tests and an increase in subjective calmness. Dextropropoxyphene impaired performance on choice reaction time and picture recognition. These data show that oral morphine may enhance performance in some measures of cognitive function, whereas dextropropoxyphene (in usual therapeutic doses) seems more likely to cause impairment. Neither opioid has substantial effects on cognition and psychomotor function compared with lorazepam." @default.
• W2009461982 created "2016-06-24" @default.
• W2009461982 creator A5011464178 @default.
• W2009461982 creator A5027286979 @default.
• W2009461982 creator A5029601596 @default.
• W2009461982 creator A5043238295 @default.
• W2009461982 creator A5050868856 @default.
• W2009461982 creator A5079016899 @default.
• W2009461982 date "2000-03-01" @default.
• W2009461982 modified "2023-10-18" @default.
• W2009461982 title "The cognitive and psychomotor effects of morphine in healthy subjects: a randomized controlled trial of repeated (four) oral doses of dextropropoxyphene, morphine, lorazepam and placebo" @default.
• W2009461982 cites W1635543723 @default.
• W2009461982 cites W1892298036 @default.
• W2009461982 cites W1972576960 @default.
• W2009461982 cites W1973136081 @default.
• W2009461982 cites W1976147062 @default.
• W2009461982 cites W1978696020 @default.
• W2009461982 cites W1979565245 @default.
• W2009461982 cites W2011551304 @default.
• W2009461982 cites W2028924962 @default.
• W2009461982 cites W2033629964 @default.
• W2009461982 cites W2053957559 @default.
• W2009461982 cites W2059032527 @default.
• W2009461982 cites W2069656904 @default.
• W2009461982 cites W2077125496 @default.
• W2009461982 cites W2078091172 @default.
• W2009461982 cites W2087591897 @default.
• W2009461982 cites W2088474612 @default.
• W2009461982 cites W2096266931 @default.
• W2009461982 cites W2434790001 @default.
• W2009461982 cites W4231599650 @default.
• W2009461982 doi "https://doi.org/10.1016/s0304-3959(99)00274-2" @default.
• W2009461982 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10692620" @default.
• W2009461982 hasPublicationYear "2000" @default.
• W2009461982 type Work @default.
• W2009461982 sameAs 2009461982 @default.
• W2009461982 citedByCount "59" @default.
• W2009461982 countsByYear W20094619822012 @default.
• W2009461982 countsByYear W20094619822013 @default.
• W2009461982 countsByYear W20094619822014 @default.
• W2009461982 countsByYear W20094619822016 @default.
• W2009461982 countsByYear W20094619822017 @default.
• W2009461982 countsByYear W20094619822018 @default.
• W2009461982 countsByYear W20094619822020 @default.
• W2009461982 countsByYear W20094619822021 @default.
• W2009461982 countsByYear W20094619822022 @default.
• W2009461982 crossrefType "journal-article" @default.
• W2009461982 hasAuthorship W2009461982A5011464178 @default.
• W2009461982 hasAuthorship W2009461982A5027286979 @default.
• W2009461982 hasAuthorship W2009461982A5029601596 @default.
• W2009461982 hasAuthorship W2009461982A5043238295 @default.
• W2009461982 hasAuthorship W2009461982A5050868856 @default.
• W2009461982 hasAuthorship W2009461982A5079016899 @default.
• W2009461982 hasConcept C118552586 @default.
• W2009461982 hasConcept C126322002 @default.
• W2009461982 hasConcept C142724271 @default.
• W2009461982 hasConcept C15744967 @default.
• W2009461982 hasConcept C164953862 @default.
• W2009461982 hasConcept C169760540 @default.
• W2009461982 hasConcept C169900460 @default.
• W2009461982 hasConcept C170493617 @default.
• W2009461982 hasConcept C192769605 @default.
• W2009461982 hasConcept C204787440 @default.
• W2009461982 hasConcept C27081682 @default.
• W2009461982 hasConcept C2777389121 @default.
• W2009461982 hasConcept C2778173252 @default.
• W2009461982 hasConcept C2779706987 @default.
• W2009461982 hasConcept C2780820201 @default.
• W2009461982 hasConcept C2781006864 @default.
• W2009461982 hasConcept C42219234 @default.
• W2009461982 hasConcept C508975757 @default.
• W2009461982 hasConcept C548259974 @default.
• W2009461982 hasConcept C71924100 @default.
• W2009461982 hasConcept C87813604 @default.
• W2009461982 hasConceptScore W2009461982C118552586 @default.
• W2009461982 hasConceptScore W2009461982C126322002 @default.
• W2009461982 hasConceptScore W2009461982C142724271 @default.
• W2009461982 hasConceptScore W2009461982C15744967 @default.
• W2009461982 hasConceptScore W2009461982C164953862 @default.
• W2009461982 hasConceptScore W2009461982C169760540 @default.
• W2009461982 hasConceptScore W2009461982C169900460 @default.
• W2009461982 hasConceptScore W2009461982C170493617 @default.
• W2009461982 hasConceptScore W2009461982C192769605 @default.
• W2009461982 hasConceptScore W2009461982C204787440 @default.
• W2009461982 hasConceptScore W2009461982C27081682 @default.
• W2009461982 hasConceptScore W2009461982C2777389121 @default.
• W2009461982 hasConceptScore W2009461982C2778173252 @default.
• W2009461982 hasConceptScore W2009461982C2779706987 @default.
• W2009461982 hasConceptScore W2009461982C2780820201 @default.
• W2009461982 hasConceptScore W2009461982C2781006864 @default.
• W2009461982 hasConceptScore W2009461982C42219234 @default.
• W2009461982 hasConceptScore W2009461982C508975757 @default.
• W2009461982 hasConceptScore W2009461982C548259974 @default.
• W2009461982 hasConceptScore W2009461982C71924100 @default.
• W2009461982 hasConceptScore W2009461982C87813604 @default.
• W2009461982 hasIssue "1" @default.
• W2009461982 hasLocation W20094619821 @default.
• W2009461982 hasLocation W20094619822 @default.

• next