FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009488462> ?p ?o ?g. }

• W2009488462 endingPage "2213" @default.
• W2009488462 startingPage "2210" @default.
• W2009488462 abstract "Major histocompatability complex class I chain-related antigen A, B (MICA, B) functions as ligands for human NKG2D receptors, which may play a role in graft rejection and cellular stress. In this study we explored the effect of ischemia/reperfusion injury (IRI) on the expression of H60 and RAE-1 (MICA, B homologues) in mice to study the protective effect of Yisheng injection (YS), an herbal preparation developed from traditional Chinese medicine. Male BALB/c mice were divided into sham, ischemic, and YS-treated groups using 90 minutes of left liver lobe ischemia. Sham control mice underwent the same operation, but without vascular occlusion. In the treated group, YS (20 mg/kg) was given before ischemia and after reperfusion for 7 days. Liver samples collected at 7 days postoperation were used for real-time quantitative polymerase chain reaction analysis, Western blotting, and immunohistochemical assays. Compared with the sham group, H60 and RAE-1 mRNA levels were increased by sevenfold and 4.5-fold in the ischemic group, respectively. After YS treatment, they were reduced by 76% and 70%, respectively. Western blotting and immunohistochemical assays showed that there was absent or faint H60 and RAE-1 expression in sham liver, but they were apparently increased in ischemic liver; however, the expressions were significantly decreased in the presence of YS. Hepatic IRI significantly increased H60 and RAE-1 expression in mouse liver. YS treatment effectively reduced this increase, seeming to attenuate NKG2D-ligand-mediated immune responses caused by IRI. This may suggest a new concept to prevent IRI and graft rejection." @default.
• W2009488462 created "2016-06-24" @default.
• W2009488462 creator A5001475931 @default.
• W2009488462 creator A5007370165 @default.
• W2009488462 creator A5007944809 @default.
• W2009488462 creator A5038602351 @default.
• W2009488462 creator A5038818617 @default.
• W2009488462 creator A5065158388 @default.
• W2009488462 creator A5073529998 @default.
• W2009488462 creator A5087937660 @default.
• W2009488462 date "2006-09-01" @default.
• W2009488462 modified "2023-10-12" @default.
• W2009488462 title "Yisheng Injection Decreases the Expression of H60 and RAE-1 Genes in Ischemic Mice Liver" @default.
• W2009488462 cites W1492543509 @default.
• W2009488462 cites W1603913234 @default.
• W2009488462 cites W1964209790 @default.
• W2009488462 cites W1964405883 @default.
• W2009488462 cites W2006202815 @default.
• W2009488462 cites W2009326258 @default.
• W2009488462 cites W2020623477 @default.
• W2009488462 cites W2024742663 @default.
• W2009488462 cites W2030019925 @default.
• W2009488462 cites W2037057992 @default.
• W2009488462 cites W205816268 @default.
• W2009488462 cites W2063067831 @default.
• W2009488462 cites W2076202028 @default.
• W2009488462 cites W2333378480 @default.
• W2009488462 doi "https://doi.org/10.1016/j.transproceed.2006.06.100" @default.
• W2009488462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16980045" @default.
• W2009488462 hasPublicationYear "2006" @default.
• W2009488462 type Work @default.
• W2009488462 sameAs 2009488462 @default.
• W2009488462 citedByCount "4" @default.
• W2009488462 crossrefType "journal-article" @default.
• W2009488462 hasAuthorship W2009488462A5001475931 @default.
• W2009488462 hasAuthorship W2009488462A5007370165 @default.
• W2009488462 hasAuthorship W2009488462A5007944809 @default.
• W2009488462 hasAuthorship W2009488462A5038602351 @default.
• W2009488462 hasAuthorship W2009488462A5038818617 @default.
• W2009488462 hasAuthorship W2009488462A5065158388 @default.
• W2009488462 hasAuthorship W2009488462A5073529998 @default.
• W2009488462 hasAuthorship W2009488462A5087937660 @default.
• W2009488462 hasConcept C104317684 @default.
• W2009488462 hasConcept C126322002 @default.
• W2009488462 hasConcept C134018914 @default.
• W2009488462 hasConcept C142724271 @default.
• W2009488462 hasConcept C154317977 @default.
• W2009488462 hasConcept C170493617 @default.
• W2009488462 hasConcept C202751555 @default.
• W2009488462 hasConcept C203014093 @default.
• W2009488462 hasConcept C204232928 @default.
• W2009488462 hasConcept C2778867473 @default.
• W2009488462 hasConcept C2780114680 @default.
• W2009488462 hasConcept C48023723 @default.
• W2009488462 hasConcept C541997718 @default.
• W2009488462 hasConcept C55493867 @default.
• W2009488462 hasConcept C71924100 @default.
• W2009488462 hasConcept C85265743 @default.
• W2009488462 hasConcept C86803240 @default.
• W2009488462 hasConceptScore W2009488462C104317684 @default.
• W2009488462 hasConceptScore W2009488462C126322002 @default.
• W2009488462 hasConceptScore W2009488462C134018914 @default.
• W2009488462 hasConceptScore W2009488462C142724271 @default.
• W2009488462 hasConceptScore W2009488462C154317977 @default.
• W2009488462 hasConceptScore W2009488462C170493617 @default.
• W2009488462 hasConceptScore W2009488462C202751555 @default.
• W2009488462 hasConceptScore W2009488462C203014093 @default.
• W2009488462 hasConceptScore W2009488462C204232928 @default.
• W2009488462 hasConceptScore W2009488462C2778867473 @default.
• W2009488462 hasConceptScore W2009488462C2780114680 @default.
• W2009488462 hasConceptScore W2009488462C48023723 @default.
• W2009488462 hasConceptScore W2009488462C541997718 @default.
• W2009488462 hasConceptScore W2009488462C55493867 @default.
• W2009488462 hasConceptScore W2009488462C71924100 @default.
• W2009488462 hasConceptScore W2009488462C85265743 @default.
• W2009488462 hasConceptScore W2009488462C86803240 @default.
• W2009488462 hasFunder F4320321001 @default.
• W2009488462 hasFunder F4320321408 @default.
• W2009488462 hasFunder F4320321543 @default.
• W2009488462 hasFunder F4320335777 @default.
• W2009488462 hasIssue "7" @default.
• W2009488462 hasLocation W20094884621 @default.
• W2009488462 hasLocation W20094884622 @default.
• W2009488462 hasOpenAccess W2009488462 @default.
• W2009488462 hasPrimaryLocation W20094884621 @default.
• W2009488462 hasRelatedWork W1963919935 @default.
• W2009488462 hasRelatedWork W1979660518 @default.
• W2009488462 hasRelatedWork W2018368842 @default.
• W2009488462 hasRelatedWork W2033472167 @default.
• W2009488462 hasRelatedWork W2034583712 @default.
• W2009488462 hasRelatedWork W2063619316 @default.
• W2009488462 hasRelatedWork W2074821979 @default.
• W2009488462 hasRelatedWork W2162471541 @default.
• W2009488462 hasRelatedWork W2169225653 @default.
• W2009488462 hasRelatedWork W2414846389 @default.
• W2009488462 hasVolume "38" @default.
• W2009488462 isParatext "false" @default.
• W2009488462 isRetracted "false" @default.

• next