Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009490993> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2009490993 endingPage "86" @default.
- W2009490993 startingPage "79" @default.
- W2009490993 abstract "The generation of titanium foams is a promising strategy for modifying the mechanical properties of intervertebral reinforcements. Thus, the aim of this study was to compare the in vitro biological response of Ti6Al4V alloys with different pore sizes for use in intervertebral implants in terms of the adhesion, proliferation, and differentiation of pre-osteoblastic cells. We studied the production of Ti6Al4V foams by powder metallurgy and the biological responses to Ti6Al4V foams were assessed in terms of different pore interconnectivities and elastic moduli. The Ti6Al4V foams obtained had similar porosities of approximately 34%, but different pore sizes (66 µm for fine Ti6Al4V and 147 µm for coarse Ti6Al4V) due to the sizes of the microsphere used. The Ti6Al4V foams had a slightly higher Young׳s modulus compared with cancellous bone. The dynamic mechanical properties of the Ti6Al4V foams were slightly low, but these materials can satisfy the requirements for intervertebral prosthesis applications. The cultured cells colonized both sizes of microspheres near the pore spaces, where they occupied almost the entire area of the microspheres when the final cell culture time was reached. No statistical differences in cell proliferation were observed; however, the cells filled the pores on fine Ti6Al4V foams but they only colonized the superficial microspheres, whereas the cells did not fill the pores on coarse Ti6Al4V foams but they were distributed throughout most of the material. In addition, the microspheres with wide pores (coarse Ti6Al4V) stimulated higher osteoblast differentiation, as demonstrated by the Alcaline Phosphatase (ALP) activity. Our in vitro results suggest that foams with wide pore facilitate internal cell colonization and stimulate osteoblast differentiation." @default.
- W2009490993 created "2016-06-24" @default.
- W2009490993 creator A5027548306 @default.
- W2009490993 creator A5029049562 @default.
- W2009490993 creator A5029229338 @default.
- W2009490993 creator A5040672664 @default.
- W2009490993 creator A5054449224 @default.
- W2009490993 creator A5056627839 @default.
- W2009490993 date "2014-11-01" @default.
- W2009490993 modified "2023-10-16" @default.
- W2009490993 title "Mechanical properties and in vitro biological response to porous titanium alloys prepared for use in intervertebral implants" @default.
- W2009490993 cites W1964727874 @default.
- W2009490993 cites W1978616686 @default.
- W2009490993 cites W2001203834 @default.
- W2009490993 cites W2022898572 @default.
- W2009490993 cites W2027871886 @default.
- W2009490993 cites W2040192889 @default.
- W2009490993 cites W2049156512 @default.
- W2009490993 cites W2051085059 @default.
- W2009490993 cites W2052652460 @default.
- W2009490993 cites W2056303138 @default.
- W2009490993 cites W2060193264 @default.
- W2009490993 cites W2078724253 @default.
- W2009490993 cites W2079801131 @default.
- W2009490993 cites W2105197065 @default.
- W2009490993 cites W2159210886 @default.
- W2009490993 doi "https://doi.org/10.1016/j.jmbbm.2014.05.029" @default.
- W2009490993 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25108271" @default.
- W2009490993 hasPublicationYear "2014" @default.
- W2009490993 type Work @default.
- W2009490993 sameAs 2009490993 @default.
- W2009490993 citedByCount "43" @default.
- W2009490993 countsByYear W20094909932015 @default.
- W2009490993 countsByYear W20094909932016 @default.
- W2009490993 countsByYear W20094909932017 @default.
- W2009490993 countsByYear W20094909932018 @default.
- W2009490993 countsByYear W20094909932019 @default.
- W2009490993 countsByYear W20094909932020 @default.
- W2009490993 countsByYear W20094909932021 @default.
- W2009490993 countsByYear W20094909932022 @default.
- W2009490993 countsByYear W20094909932023 @default.
- W2009490993 crossrefType "journal-article" @default.
- W2009490993 hasAuthorship W2009490993A5027548306 @default.
- W2009490993 hasAuthorship W2009490993A5029049562 @default.
- W2009490993 hasAuthorship W2009490993A5029229338 @default.
- W2009490993 hasAuthorship W2009490993A5040672664 @default.
- W2009490993 hasAuthorship W2009490993A5054449224 @default.
- W2009490993 hasAuthorship W2009490993A5056627839 @default.
- W2009490993 hasConcept C136229726 @default.
- W2009490993 hasConcept C142724271 @default.
- W2009490993 hasConcept C159985019 @default.
- W2009490993 hasConcept C171250308 @default.
- W2009490993 hasConcept C191897082 @default.
- W2009490993 hasConcept C192562407 @default.
- W2009490993 hasConcept C2776350087 @default.
- W2009490993 hasConcept C2778414984 @default.
- W2009490993 hasConcept C2780026712 @default.
- W2009490993 hasConcept C43486711 @default.
- W2009490993 hasConcept C506065880 @default.
- W2009490993 hasConcept C6648577 @default.
- W2009490993 hasConcept C71924100 @default.
- W2009490993 hasConcept C8953137 @default.
- W2009490993 hasConceptScore W2009490993C136229726 @default.
- W2009490993 hasConceptScore W2009490993C142724271 @default.
- W2009490993 hasConceptScore W2009490993C159985019 @default.
- W2009490993 hasConceptScore W2009490993C171250308 @default.
- W2009490993 hasConceptScore W2009490993C191897082 @default.
- W2009490993 hasConceptScore W2009490993C192562407 @default.
- W2009490993 hasConceptScore W2009490993C2776350087 @default.
- W2009490993 hasConceptScore W2009490993C2778414984 @default.
- W2009490993 hasConceptScore W2009490993C2780026712 @default.
- W2009490993 hasConceptScore W2009490993C43486711 @default.
- W2009490993 hasConceptScore W2009490993C506065880 @default.
- W2009490993 hasConceptScore W2009490993C6648577 @default.
- W2009490993 hasConceptScore W2009490993C71924100 @default.
- W2009490993 hasConceptScore W2009490993C8953137 @default.
- W2009490993 hasLocation W20094909931 @default.
- W2009490993 hasLocation W20094909932 @default.
- W2009490993 hasOpenAccess W2009490993 @default.
- W2009490993 hasPrimaryLocation W20094909931 @default.
- W2009490993 hasRelatedWork W1494185026 @default.
- W2009490993 hasRelatedWork W2008399382 @default.
- W2009490993 hasRelatedWork W2062169110 @default.
- W2009490993 hasRelatedWork W2300044447 @default.
- W2009490993 hasRelatedWork W2556092005 @default.
- W2009490993 hasRelatedWork W2586935247 @default.
- W2009490993 hasRelatedWork W3021945041 @default.
- W2009490993 hasRelatedWork W3096312914 @default.
- W2009490993 hasRelatedWork W341228048 @default.
- W2009490993 hasRelatedWork W4234922880 @default.
- W2009490993 hasVolume "39" @default.
- W2009490993 isParatext "false" @default.
- W2009490993 isRetracted "false" @default.
- W2009490993 magId "2009490993" @default.
- W2009490993 workType "article" @default.