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- W2009496479 abstract "Irritable bowel syndrome (IBS) is a gastrointestinal disorder characterized by chronic abdominal pain associated with altered bowel habits. Since the prevalence of IBS is very high and thus, involves elevated health-care costs, treatment of this condition by methods other than prescribed medicines could be beneficial. β-(1,3)-d-glucan with β-(1,6) branches (β-glucan) has been used as a nutritional supplement for many years. In this study, we examined the effect of β-glucan on fecal pellet output and visceral pain response in animal models of IBS. Oral administration of β-glucan suppressed the restraint stress- or drug-induced fecal pellet output. β-Glucan also suppressed the visceral pain response to colorectal distension. These results suggest that β-glucan could be beneficial for the treatment and prevention of IBS." @default.
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- W2009496479 date "2012-04-01" @default.
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- W2009496479 title "Effects of β-(1,3–1,6)-d-glucan on irritable bowel syndrome-related colonic hypersensitivity" @default.
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- W2009496479 doi "https://doi.org/10.1016/j.bbrc.2012.03.015" @default.
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