FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009496653> ?p ?o ?g. }

• W2009496653 endingPage "670" @default.
• W2009496653 startingPage "655" @default.
• W2009496653 abstract "We have used a rat brain-slice preparation to study the effects of some cholinomimetic and amino acid agonists and antagonists on the discharge frequency of neurones in the interpeduncular nucleus (i.p.n.), and on the response of these neurones to electrical stimulation of their main excitatory input, the fasciculus retroflexus of Meynert (f.r.m.). A high proportion of i.p.n. neurones were excited by carbachol, acetylcholine (ACh) and muscarine, but methacholine was less effective. The amino acids L-glutamate and L-aspartate were highly effective stimulants of i.p.n. neurones. The responses to ACh or carbachol were greatly reduced by the nicotinic blocking agents hexamethonium, d-tubocurarine and mecamylamine but only slightly reduced by atropine. The response to muscarine was abolished by low doses of atropine. Alpha-Bungarotoxin did not block the response of i.p.n. neurones to f.r.m. stimulation or to cholinomimetic agonists. The response of i.p.n. neurones to f.r.m. stimulation was not appreciably affected by high doses of nicotinic antagonists or atropine nor was there any enhancement of the response by physostigmine. The amino acid antagonists gamma-D-glutamylglycine (gamma DGG) and 2-amino phosphonovalerate (2-APV) were effective blockers of the response to f.r.m. stimulation and preferentially reduced responses to aspartate while having little effect on responses to glutamate or cholinomimetic agonists. It is concluded that ACh is an unlikely candidate for transmitter in this pathway despite abundant neurochemical evidence in its favour. It is more likely that the transmitter is an excitatory amino acid, probably an aspartate-like substance." @default.
• W2009496653 created "2016-06-24" @default.
• W2009496653 creator A5027714194 @default.
• W2009496653 creator A5058047982 @default.
• W2009496653 creator A5065974322 @default.
• W2009496653 date "1983-08-01" @default.
• W2009496653 modified "2023-09-25" @default.
• W2009496653 title "Chemical transmission in the rat interpeduncular nucleus in vitro." @default.
• W2009496653 cites W1972770271 @default.
• W2009496653 cites W1974444464 @default.
• W2009496653 cites W1979210685 @default.
• W2009496653 cites W1985075895 @default.
• W2009496653 cites W1987107045 @default.
• W2009496653 cites W1991409318 @default.
• W2009496653 cites W1997924070 @default.
• W2009496653 cites W1998208830 @default.
• W2009496653 cites W2001744744 @default.
• W2009496653 cites W2001944815 @default.
• W2009496653 cites W2003289980 @default.
• W2009496653 cites W2005626208 @default.
• W2009496653 cites W2006055606 @default.
• W2009496653 cites W2006667830 @default.
• W2009496653 cites W2011390053 @default.
• W2009496653 cites W2011519970 @default.
• W2009496653 cites W2014325188 @default.
• W2009496653 cites W2020107272 @default.
• W2009496653 cites W2020244809 @default.
• W2009496653 cites W2020302857 @default.
• W2009496653 cites W2022665453 @default.
• W2009496653 cites W2035173239 @default.
• W2009496653 cites W2038758804 @default.
• W2009496653 cites W2047614695 @default.
• W2009496653 cites W2056415280 @default.
• W2009496653 cites W2058747161 @default.
• W2009496653 cites W2059504025 @default.
• W2009496653 cites W2063383058 @default.
• W2009496653 cites W2067447823 @default.
• W2009496653 cites W2072453676 @default.
• W2009496653 cites W2072744630 @default.
• W2009496653 cites W2081011380 @default.
• W2009496653 cites W2083448443 @default.
• W2009496653 cites W2087444720 @default.
• W2009496653 cites W2089800844 @default.
• W2009496653 cites W2150561524 @default.
• W2009496653 cites W2151368240 @default.
• W2009496653 cites W2424807923 @default.
• W2009496653 doi "https://doi.org/10.1113/jphysiol.1983.sp014831" @default.
• W2009496653 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1195356" @default.
• W2009496653 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6137562" @default.
• W2009496653 hasPublicationYear "1983" @default.
• W2009496653 type Work @default.
• W2009496653 sameAs 2009496653 @default.
• W2009496653 citedByCount "76" @default.
• W2009496653 countsByYear W20094966532012 @default.
• W2009496653 countsByYear W20094966532014 @default.
• W2009496653 countsByYear W20094966532018 @default.
• W2009496653 countsByYear W20094966532021 @default.
• W2009496653 countsByYear W20094966532022 @default.
• W2009496653 crossrefType "journal-article" @default.
• W2009496653 hasAuthorship W2009496653A5027714194 @default.
• W2009496653 hasAuthorship W2009496653A5058047982 @default.
• W2009496653 hasAuthorship W2009496653A5065974322 @default.
• W2009496653 hasBestOaLocation W20094966531 @default.
• W2009496653 hasConcept C112592302 @default.
• W2009496653 hasConcept C126322002 @default.
• W2009496653 hasConcept C134018914 @default.
• W2009496653 hasConcept C170493617 @default.
• W2009496653 hasConcept C185592680 @default.
• W2009496653 hasConcept C188987157 @default.
• W2009496653 hasConcept C22885893 @default.
• W2009496653 hasConcept C24998067 @default.
• W2009496653 hasConcept C2775859210 @default.
• W2009496653 hasConcept C2775893369 @default.
• W2009496653 hasConcept C2775910092 @default.
• W2009496653 hasConcept C2776663719 @default.
• W2009496653 hasConcept C2776880047 @default.
• W2009496653 hasConcept C2778988552 @default.
• W2009496653 hasConcept C2780841807 @default.
• W2009496653 hasConcept C2909754679 @default.
• W2009496653 hasConcept C33789571 @default.
• W2009496653 hasConcept C44107871 @default.
• W2009496653 hasConcept C529278444 @default.
• W2009496653 hasConcept C552161191 @default.
• W2009496653 hasConcept C55493867 @default.
• W2009496653 hasConcept C61174792 @default.
• W2009496653 hasConcept C71924100 @default.
• W2009496653 hasConcept C86803240 @default.
• W2009496653 hasConcept C98274493 @default.
• W2009496653 hasConceptScore W2009496653C112592302 @default.
• W2009496653 hasConceptScore W2009496653C126322002 @default.
• W2009496653 hasConceptScore W2009496653C134018914 @default.
• W2009496653 hasConceptScore W2009496653C170493617 @default.
• W2009496653 hasConceptScore W2009496653C185592680 @default.
• W2009496653 hasConceptScore W2009496653C188987157 @default.
• W2009496653 hasConceptScore W2009496653C22885893 @default.
• W2009496653 hasConceptScore W2009496653C24998067 @default.
• W2009496653 hasConceptScore W2009496653C2775859210 @default.
• W2009496653 hasConceptScore W2009496653C2775893369 @default.

• next