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- W2009558940 abstract "Abstract Acid-base relation of blood and CSF with respect to respiratory regulation was studied in four Sherpa altitude residents and five lowlanders at 4880 m in Himalayas for two months. Mean CSF data in three Sherpas and four lowlanders respectively were: pH 7.328 and 7.374, P CO 2 37.7 and 35.8 mm Hg; HCO 3 − 19.1 and 20.1, Na + 151 and 144, K + 3.4 and 2.9, meq/l; lactate 26.8 and 27.7 mg/100 ml. Respective alveolar and arterial data for four Sherpas and five lowlanders were: Pa CO 2 28.6 and 25.9 mm Hg, Pa O 2 49.4 and 48.7 mm Hg, pH 7.399 and 7.424, HCO 3 − 17.1 and 16.5 meq/l, lactate 18.8 and 26.2 mg/100 ml blood, hemoglobin 19.0 and 19.3 g %. It is concluded that lowlanders did not quite achieve Sherpas' acid-base status and that the difference is related to Sherpas' less ventilatory response to existing hypoxia. These and other published data on chronic acid-base homeostasis have been analyzed to define blood-CSF pH relationship. CSF pH varies with blood pH but only sluggishly. This relationship differs in respiratory and metabolic alterations" @default.
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- W2009558940 date "1967-05-01" @default.
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- W2009558940 title "Acid-base in sherpa altitude residents and lowlanders at 4880 M" @default.
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- W2009558940 doi "https://doi.org/10.1016/0034-5687(67)90037-0" @default.
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