Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009580808> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2009580808 endingPage "1060" @default.
- W2009580808 startingPage "1056" @default.
- W2009580808 abstract "Background. A genetic predisposition to impaired detoxification of oxidative or chemical stress could play a role in the etiology of perinatal mortality. In this pilot study we investigated the risk of perinatal mortality in relation to genetic polymorphism in microsomal epoxide hydrolase (EPHX) and glutathione S ‐transferase P1 (GSTP1) in women who experienced perinatal mortality caused by placental pathology, congenital disorders and complications of premature delivery and their male partners. Methods. Genomic DNA of couples (72 females and 46 males) with a history of perinatal mortality and control couples (71 females and 66 males) with no complications in their obstetric history were analyzed for the presence of the polymorphisms in exon 3 of EPHX (Tyr113His) and GSTP1 (Ile105Val). Results. A similar distribution of the GSTP1 polymorphism was found in all subjects investigated. In women who experienced perinatal mortality, we demonstrated a higher prevalence of the EPHX His 113 /His 113 genotype, which could result in a lower enzyme activity, compared with controls (25% vs. 9%; χ 2 = 5.7 and p < 0.02), with an odds ratio (95% confidence interval) of 3.5 (1.1–12.7). Conclusion. Our results suggest that the maternal Tyr113His polymorphism in EPHX may be a risk factor for perinatal mortality. However, more research is needed to determine the implication of this finding." @default.
- W2009580808 created "2016-06-24" @default.
- W2009580808 creator A5016205726 @default.
- W2009580808 creator A5018189793 @default.
- W2009580808 creator A5025993114 @default.
- W2009580808 creator A5034626585 @default.
- W2009580808 creator A5048880494 @default.
- W2009580808 creator A5075145005 @default.
- W2009580808 date "2004-10-15" @default.
- W2009580808 modified "2023-10-17" @default.
- W2009580808 title "The Tyr113His polymorphism in exon 3 of the microsomal epoxide hydrolase gene is a risk factor for perinatal mortality" @default.
- W2009580808 cites W171819190 @default.
- W2009580808 cites W1891743807 @default.
- W2009580808 cites W1992376732 @default.
- W2009580808 cites W2018692482 @default.
- W2009580808 cites W2022821656 @default.
- W2009580808 cites W2033045194 @default.
- W2009580808 cites W2039041084 @default.
- W2009580808 cites W2051271179 @default.
- W2009580808 cites W2062493285 @default.
- W2009580808 cites W2068309419 @default.
- W2009580808 cites W2089287458 @default.
- W2009580808 cites W2099419193 @default.
- W2009580808 cites W2113034203 @default.
- W2009580808 cites W2120739842 @default.
- W2009580808 cites W2143272819 @default.
- W2009580808 cites W4238249221 @default.
- W2009580808 cites W4239229629 @default.
- W2009580808 cites W4295750166 @default.
- W2009580808 doi "https://doi.org/10.1111/j.0001-6349.2004.00455.x" @default.
- W2009580808 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15488121" @default.
- W2009580808 hasPublicationYear "2004" @default.
- W2009580808 type Work @default.
- W2009580808 sameAs 2009580808 @default.
- W2009580808 citedByCount "3" @default.
- W2009580808 countsByYear W20095808082013 @default.
- W2009580808 crossrefType "journal-article" @default.
- W2009580808 hasAuthorship W2009580808A5016205726 @default.
- W2009580808 hasAuthorship W2009580808A5018189793 @default.
- W2009580808 hasAuthorship W2009580808A5025993114 @default.
- W2009580808 hasAuthorship W2009580808A5034626585 @default.
- W2009580808 hasAuthorship W2009580808A5048880494 @default.
- W2009580808 hasAuthorship W2009580808A5075145005 @default.
- W2009580808 hasConcept C101819947 @default.
- W2009580808 hasConcept C104317684 @default.
- W2009580808 hasConcept C126322002 @default.
- W2009580808 hasConcept C135763542 @default.
- W2009580808 hasConcept C156957248 @default.
- W2009580808 hasConcept C202751555 @default.
- W2009580808 hasConcept C2776671928 @default.
- W2009580808 hasConcept C2779134260 @default.
- W2009580808 hasConcept C2780122483 @default.
- W2009580808 hasConcept C50440223 @default.
- W2009580808 hasConcept C54355233 @default.
- W2009580808 hasConcept C67636389 @default.
- W2009580808 hasConcept C71924100 @default.
- W2009580808 hasConcept C86803240 @default.
- W2009580808 hasConcept C87644729 @default.
- W2009580808 hasConceptScore W2009580808C101819947 @default.
- W2009580808 hasConceptScore W2009580808C104317684 @default.
- W2009580808 hasConceptScore W2009580808C126322002 @default.
- W2009580808 hasConceptScore W2009580808C135763542 @default.
- W2009580808 hasConceptScore W2009580808C156957248 @default.
- W2009580808 hasConceptScore W2009580808C202751555 @default.
- W2009580808 hasConceptScore W2009580808C2776671928 @default.
- W2009580808 hasConceptScore W2009580808C2779134260 @default.
- W2009580808 hasConceptScore W2009580808C2780122483 @default.
- W2009580808 hasConceptScore W2009580808C50440223 @default.
- W2009580808 hasConceptScore W2009580808C54355233 @default.
- W2009580808 hasConceptScore W2009580808C67636389 @default.
- W2009580808 hasConceptScore W2009580808C71924100 @default.
- W2009580808 hasConceptScore W2009580808C86803240 @default.
- W2009580808 hasConceptScore W2009580808C87644729 @default.
- W2009580808 hasIssue "11" @default.
- W2009580808 hasLocation W20095808081 @default.
- W2009580808 hasLocation W20095808082 @default.
- W2009580808 hasOpenAccess W2009580808 @default.
- W2009580808 hasPrimaryLocation W20095808081 @default.
- W2009580808 hasRelatedWork W1541993819 @default.
- W2009580808 hasRelatedWork W2022720479 @default.
- W2009580808 hasRelatedWork W2027888835 @default.
- W2009580808 hasRelatedWork W2029795834 @default.
- W2009580808 hasRelatedWork W2046240925 @default.
- W2009580808 hasRelatedWork W2089302594 @default.
- W2009580808 hasRelatedWork W2156618348 @default.
- W2009580808 hasRelatedWork W2159036823 @default.
- W2009580808 hasRelatedWork W2165382806 @default.
- W2009580808 hasRelatedWork W2167085765 @default.
- W2009580808 hasVolume "83" @default.
- W2009580808 isParatext "false" @default.
- W2009580808 isRetracted "false" @default.
- W2009580808 magId "2009580808" @default.
- W2009580808 workType "article" @default.