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- W2009587339 abstract "Dem Prozess der Zellmigration liegen physikalische Gesetzmasigkeiten zu Grunde. Ein tiefergehendes Verstandnis der Mechanik lebender Zellen ist bei zellularen Prozessen wie z.B. der Migration von Tumorzellen durch eine 3-D-Matrix von entscheidender Bedeutung. Es konnte sich ein zellmechanischer Parameter – besser als einzelne Proteine – als Marker eignen, um routinemasig in der Tumordiagnostik eingesetzt zu werden. Die Erforschung der Mechanik von lebenden Zellen tragt zu einem besseren Verstandnis von Krebserkrankungen bei – insbesondere bei dem Prozess der Tumor-Metastasierung durch Invasion von Krebszellen in das Bindegewebe.The process of cell migration is definied by biochemical and biophysical properties of the invading cells. Accelarated investigations in the field of biomechanics are of high impact regarding the process of the migration into a 3-D matrix of tumor cells. In contrast to use of several protein markers that determine tumor malignancy, a single cell mechanical parameter may delevop as a reliable, standard tool for tumor diagnostics. The cell mechanics of living cells shed light on tumor disease especially on the process of metastasis that involves the invasion of tumor cells through connective tissue." @default.
- W2009587339 created "2016-06-24" @default.
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- W2009587339 date "2009-02-01" @default.
- W2009587339 modified "2023-10-05" @default.
- W2009587339 title "Mechanische Experimente an lebenden Zellen. Perspektiven für die Krebsforschung" @default.
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- W2009587339 doi "https://doi.org/10.1002/biuz.200910384" @default.
- W2009587339 hasPublicationYear "2009" @default.
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