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• W2009588744 startingPage "401" @default.
• W2009588744 abstract "A vaccine is urgently needed to prevent cattle neosporosis. This infectious disease is caused by the parasite Neospora caninum, a complex biological system with multifaceted life cycles. An in silico vaccine discovery approach attempts to transform digital abstractions of this system into adequate knowledge to predict candidates. Researchers need current information to implement such an approach, such as understanding evasion mechanisms of the immune system, type of immune response to elicit, availability of data and prediction programs, and statistical models to analyze predictions. Taken together, an in silico approach involves assembly of an intricate jigsaw of interdisciplinary and interdependent knowledge. In this review, we focus on the approach influencing vaccine development against Neospora caninum, which can be generalized to other pathogenic apicomplexans." @default.
• W2009588744 created "2016-06-24" @default.
• W2009588744 creator A5007566988 @default.
• W2009588744 creator A5045984899 @default.
• W2009588744 creator A5080194823 @default.
• W2009588744 date "2014-08-01" @default.
• W2009588744 modified "2023-10-01" @default.
• W2009588744 title "Discovering a vaccine against neosporosis using computers: is it feasible?" @default.
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• W2009588744 doi "https://doi.org/10.1016/j.pt.2014.06.004" @default.
• W2009588744 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25028089" @default.

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