FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009596768> ?p ?o ?g. }

• W2009596768 endingPage "e34660" @default.
• W2009596768 startingPage "e34660" @default.
• W2009596768 abstract "Despite the public health importance of Salmonella infection in pigs, little is known about the associated dynamics of fecal shedding and immunity. In this study, we investigated the transitions of pigs through the states of Salmonella fecal shedding and immune response post-Salmonella inoculation as affected by the challenge dose and serotype. Continuous-time multistate Markov models were developed using published experimental data. The model for shedding had four transient states, of which two were shedding (continuous and intermittent shedding) and two non-shedding (latency and intermittent non-shedding), and one absorbing state representing permanent cessation of shedding. The immune response model had two transient states representing responses below and above the seroconversion level. The effects of two doses [low (0.65×106 CFU/pig) and high (0.65×109 CFU/pig)] and four serotypes (Salmonella Yoruba, Salmonella Cubana, Salmonella Typhimurium, and Salmonella Derby) on the models' transition intensities were evaluated using a proportional intensities model. Results indicated statistically significant effects of the challenge dose and serotype on the dynamics of shedding and immune response. The time spent in the specific states was also estimated. Continuous shedding was on average 10–26 days longer, while intermittent non-shedding was 2–4 days shorter, in pigs challenged with the high compared to low dose. Interestingly, among pigs challenged with the high dose, the continuous and intermittent shedding states were on average up to 10–17 and 3–4 days longer, respectively, in pigs infected with S. Cubana compared to the other three serotypes. Pigs challenged with the high dose of S. Typhimurium or S. Derby seroconverted on average up to 8–11 days faster compared to the low dose. These findings highlight that Salmonella fecal shedding and immune response following Salmonella challenge are dose- and serotype-dependent and that the detection of specific Salmonella strains and immune responses in pigs are time-sensitive." @default.
• W2009596768 created "2016-06-24" @default.
• W2009596768 creator A5003611432 @default.
• W2009596768 creator A5011012307 @default.
• W2009596768 creator A5015455682 @default.
• W2009596768 creator A5066582203 @default.
• W2009596768 date "2012-04-16" @default.
• W2009596768 modified "2023-09-25" @default.
• W2009596768 title "Salmonella Fecal Shedding and Immune Responses are Dose- and Serotype- Dependent in Pigs" @default.
• W2009596768 cites W103655302 @default.
• W2009596768 cites W1489904087 @default.
• W2009596768 cites W1981023657 @default.
• W2009596768 cites W1981298860 @default.
• W2009596768 cites W1987780429 @default.
• W2009596768 cites W1988945183 @default.
• W2009596768 cites W1991630289 @default.
• W2009596768 cites W1992439831 @default.
• W2009596768 cites W2027385701 @default.
• W2009596768 cites W2051804302 @default.
• W2009596768 cites W2057526070 @default.
• W2009596768 cites W2065155580 @default.
• W2009596768 cites W2074120219 @default.
• W2009596768 cites W2089698443 @default.
• W2009596768 cites W2099952367 @default.
• W2009596768 cites W2111289218 @default.
• W2009596768 cites W2113013224 @default.
• W2009596768 cites W2115029253 @default.
• W2009596768 cites W2118477036 @default.
• W2009596768 cites W2123952810 @default.
• W2009596768 cites W2127707725 @default.
• W2009596768 cites W2127820800 @default.
• W2009596768 cites W2136842631 @default.
• W2009596768 cites W2158303422 @default.
• W2009596768 cites W2160497761 @default.
• W2009596768 cites W2165567383 @default.
• W2009596768 cites W2917523352 @default.
• W2009596768 cites W41937443 @default.
• W2009596768 doi "https://doi.org/10.1371/journal.pone.0034660" @default.
• W2009596768 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3327719" @default.
• W2009596768 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22523553" @default.
• W2009596768 hasPublicationYear "2012" @default.
• W2009596768 type Work @default.
• W2009596768 sameAs 2009596768 @default.
• W2009596768 citedByCount "22" @default.
• W2009596768 countsByYear W20095967682012 @default.
• W2009596768 countsByYear W20095967682013 @default.
• W2009596768 countsByYear W20095967682014 @default.
• W2009596768 countsByYear W20095967682016 @default.
• W2009596768 countsByYear W20095967682017 @default.
• W2009596768 countsByYear W20095967682018 @default.
• W2009596768 countsByYear W20095967682019 @default.
• W2009596768 countsByYear W20095967682020 @default.
• W2009596768 countsByYear W20095967682022 @default.
• W2009596768 countsByYear W20095967682023 @default.
• W2009596768 crossrefType "journal-article" @default.
• W2009596768 hasAuthorship W2009596768A5003611432 @default.
• W2009596768 hasAuthorship W2009596768A5011012307 @default.
• W2009596768 hasAuthorship W2009596768A5015455682 @default.
• W2009596768 hasAuthorship W2009596768A5066582203 @default.
• W2009596768 hasBestOaLocation W20095967681 @default.
• W2009596768 hasConcept C10389963 @default.
• W2009596768 hasConcept C12914427 @default.
• W2009596768 hasConcept C159047783 @default.
• W2009596768 hasConcept C203014093 @default.
• W2009596768 hasConcept C2522874641 @default.
• W2009596768 hasConcept C2779341262 @default.
• W2009596768 hasConcept C2781065037 @default.
• W2009596768 hasConcept C523546767 @default.
• W2009596768 hasConcept C54355233 @default.
• W2009596768 hasConcept C61716771 @default.
• W2009596768 hasConcept C86803240 @default.
• W2009596768 hasConcept C8891405 @default.
• W2009596768 hasConcept C89423630 @default.
• W2009596768 hasConceptScore W2009596768C10389963 @default.
• W2009596768 hasConceptScore W2009596768C12914427 @default.
• W2009596768 hasConceptScore W2009596768C159047783 @default.
• W2009596768 hasConceptScore W2009596768C203014093 @default.
• W2009596768 hasConceptScore W2009596768C2522874641 @default.
• W2009596768 hasConceptScore W2009596768C2779341262 @default.
• W2009596768 hasConceptScore W2009596768C2781065037 @default.
• W2009596768 hasConceptScore W2009596768C523546767 @default.
• W2009596768 hasConceptScore W2009596768C54355233 @default.
• W2009596768 hasConceptScore W2009596768C61716771 @default.
• W2009596768 hasConceptScore W2009596768C86803240 @default.
• W2009596768 hasConceptScore W2009596768C8891405 @default.
• W2009596768 hasConceptScore W2009596768C89423630 @default.
• W2009596768 hasIssue "4" @default.
• W2009596768 hasLocation W20095967681 @default.
• W2009596768 hasLocation W20095967682 @default.
• W2009596768 hasLocation W20095967683 @default.
• W2009596768 hasLocation W20095967684 @default.
• W2009596768 hasLocation W20095967685 @default.
• W2009596768 hasLocation W20095967686 @default.
• W2009596768 hasOpenAccess W2009596768 @default.
• W2009596768 hasPrimaryLocation W20095967681 @default.
• W2009596768 hasRelatedWork W1799115436 @default.
• W2009596768 hasRelatedWork W1811138560 @default.
• W2009596768 hasRelatedWork W1990143030 @default.

• next