Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009615509> ?p ?o ?g. }
- W2009615509 endingPage "444" @default.
- W2009615509 startingPage "431" @default.
- W2009615509 abstract "Natural infection with Marek's disease virus occurs through the respiratory mucosa after chickens inhale dander shed from infected chickens. The early events in the lung following exposure to the feather and squamous epithelial cell debris containing the viral particles remain unclear. In order to elucidate the virological and immunological consequences of MDV infection for the respiratory tract, chickens were infected by intratracheal administration of infective dander. Differences between susceptible and resistant chickens were immediately apparent, with delayed viral replication and earlier onset of interferon (IFN)-γ production in the latter. CD4+ and CD8+ T cells surrounded infected cells in the lung. Although viral replication was evident in macrophages, pulmonary B cells were the main target cell type in susceptible chickens following intratracheal infection with MDV. In accordance, depletion of B cells curtailed viremia and substantially affected pathogenesis in susceptible chickens. Together the data described here demonstrate the role of pulmonary B cells as the primary and predominant target cells and their importance for MDV pathogenesis." @default.
- W2009615509 created "2016-06-24" @default.
- W2009615509 creator A5013792622 @default.
- W2009615509 creator A5020774630 @default.
- W2009615509 creator A5029865336 @default.
- W2009615509 creator A5051951431 @default.
- W2009615509 creator A5067969773 @default.
- W2009615509 creator A5073885877 @default.
- W2009615509 date "2009-12-01" @default.
- W2009615509 modified "2023-09-27" @default.
- W2009615509 title "Early Replication in Pulmonary B Cells After Infection with Marek's Disease Herpesvirus by the Respiratory Route" @default.
- W2009615509 cites W1485925164 @default.
- W2009615509 cites W1524823709 @default.
- W2009615509 cites W1705737383 @default.
- W2009615509 cites W1732088578 @default.
- W2009615509 cites W1896351749 @default.
- W2009615509 cites W1933902873 @default.
- W2009615509 cites W1964831939 @default.
- W2009615509 cites W1965056999 @default.
- W2009615509 cites W1967837085 @default.
- W2009615509 cites W1978163558 @default.
- W2009615509 cites W1980120595 @default.
- W2009615509 cites W1982152501 @default.
- W2009615509 cites W1983199297 @default.
- W2009615509 cites W1984912682 @default.
- W2009615509 cites W2010596055 @default.
- W2009615509 cites W2011526845 @default.
- W2009615509 cites W2014166883 @default.
- W2009615509 cites W2026826062 @default.
- W2009615509 cites W2030506232 @default.
- W2009615509 cites W2032556930 @default.
- W2009615509 cites W2042190487 @default.
- W2009615509 cites W2043720315 @default.
- W2009615509 cites W2046518060 @default.
- W2009615509 cites W2049813924 @default.
- W2009615509 cites W2049958554 @default.
- W2009615509 cites W2060077270 @default.
- W2009615509 cites W2070658777 @default.
- W2009615509 cites W2075629632 @default.
- W2009615509 cites W2084524345 @default.
- W2009615509 cites W2085548233 @default.
- W2009615509 cites W2085934870 @default.
- W2009615509 cites W2088254926 @default.
- W2009615509 cites W2093855739 @default.
- W2009615509 cites W2093873830 @default.
- W2009615509 cites W2121904354 @default.
- W2009615509 cites W2131886491 @default.
- W2009615509 cites W2132730938 @default.
- W2009615509 cites W2136149552 @default.
- W2009615509 cites W2154257715 @default.
- W2009615509 cites W2167333301 @default.
- W2009615509 cites W2287982492 @default.
- W2009615509 cites W2326464095 @default.
- W2009615509 cites W2908680834 @default.
- W2009615509 cites W4230205586 @default.
- W2009615509 cites W4237853320 @default.
- W2009615509 cites W4254344739 @default.
- W2009615509 cites W4301910497 @default.
- W2009615509 cites W4302337871 @default.
- W2009615509 cites W4302573614 @default.
- W2009615509 doi "https://doi.org/10.1089/vim.2009.0047" @default.
- W2009615509 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19951180" @default.
- W2009615509 hasPublicationYear "2009" @default.
- W2009615509 type Work @default.
- W2009615509 sameAs 2009615509 @default.
- W2009615509 citedByCount "53" @default.
- W2009615509 countsByYear W20096155092012 @default.
- W2009615509 countsByYear W20096155092013 @default.
- W2009615509 countsByYear W20096155092014 @default.
- W2009615509 countsByYear W20096155092015 @default.
- W2009615509 countsByYear W20096155092016 @default.
- W2009615509 countsByYear W20096155092017 @default.
- W2009615509 countsByYear W20096155092018 @default.
- W2009615509 countsByYear W20096155092019 @default.
- W2009615509 countsByYear W20096155092020 @default.
- W2009615509 countsByYear W20096155092021 @default.
- W2009615509 countsByYear W20096155092022 @default.
- W2009615509 countsByYear W20096155092023 @default.
- W2009615509 crossrefType "journal-article" @default.
- W2009615509 hasAuthorship W2009615509A5013792622 @default.
- W2009615509 hasAuthorship W2009615509A5020774630 @default.
- W2009615509 hasAuthorship W2009615509A5029865336 @default.
- W2009615509 hasAuthorship W2009615509A5051951431 @default.
- W2009615509 hasAuthorship W2009615509A5067969773 @default.
- W2009615509 hasAuthorship W2009615509A5073885877 @default.
- W2009615509 hasBestOaLocation W20096155092 @default.
- W2009615509 hasConcept C105702510 @default.
- W2009615509 hasConcept C126322002 @default.
- W2009615509 hasConcept C12914427 @default.
- W2009615509 hasConcept C140704245 @default.
- W2009615509 hasConcept C159047783 @default.
- W2009615509 hasConcept C167672396 @default.
- W2009615509 hasConcept C203014093 @default.
- W2009615509 hasConcept C2522874641 @default.
- W2009615509 hasConcept C2776178377 @default.
- W2009615509 hasConcept C2776185481 @default.
- W2009615509 hasConcept C2777714996 @default.
- W2009615509 hasConcept C2779644171 @default.