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• W2009631726 abstract "Little is known about the effect of pharmacotherapy in the prevention of post-traumatic stress disorder (PTSD) relapse.To assess the efficacy and tolerability of fluoxetine in preventing PTSD relapse.This was a double-blind, randomised, placebo-controlled study. Following 12 weeks of acute treatment, patients who responded were rerandomised and continued in a 24-week relapse prevention phase with fluoxetine (n=69) or placebo (n=62). The primary efficacy assessment was the prevention of PTSD relapse, based on the time to relapse.Patients in the fluoxetine/fluoxetine group were less likely to relapse than patients in the fluoxetine/placebo group (P=0.027). There were no clinically significant differences in treatment-emergent adverse events between treatment groups.Fluoxetine is effective and well tolerated in the prevention of PTSD relapse for up to 6 months." @default.
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• W2009631726 date "2002-10-01" @default.
• W2009631726 modified "2023-09-25" @default.
• W2009631726 title "Fluoxetine <i>v</i>. placebo in prevention of relapse in post-traumatic stress disorder" @default.
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• W2009631726 doi "https://doi.org/10.1192/bjp.181.4.315" @default.
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