Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009658836> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2009658836 abstract "The regulation of the human growth hormone (hGH) gene by 1,25(OH)2D3 is a mechanism which is poorly understood. The objective of this study was to investigate whether the hGH gene has DNA recognition elements for the DNA binding domain of the vitamin D receptor. Using gel retardation assays and footprinting techniques, two high-affinity binding sites, denominated F1 and F2, were identified in the 5'-flanking sequence of hGH. The distal site, F1, located at -59 bp is made up of an imperfect direct repeat separated by 3 bp and showed a high degree of similarity with other known vitamin D response elements (VDREs). The proximal site, F2, located at -36 bp showed a single 7-bp sequence, which is different from other known VDREs. The location of both sites (F1 near the GHF-1/Pit-1 response element, F2 contacting the TATA box) suggests that the vitamin D receptor by itself or through interference with other transcriptional factors may modulate hGH expression." @default.
- W2009658836 created "2016-06-24" @default.
- W2009658836 creator A5017535959 @default.
- W2009658836 creator A5044168126 @default.
- W2009658836 creator A5054391481 @default.
- W2009658836 creator A5084878846 @default.
- W2009658836 date "1998-06-01" @default.
- W2009658836 modified "2023-10-03" @default.
- W2009658836 title "High-Affinity Binding Sites to the Vitamin D Receptor DNA Binding Domain in the Human Growth Hormone Promoter" @default.
- W2009658836 cites W1519455435 @default.
- W2009658836 cites W1556887581 @default.
- W2009658836 cites W1574093570 @default.
- W2009658836 cites W1819829467 @default.
- W2009658836 cites W1891860773 @default.
- W2009658836 cites W1964685458 @default.
- W2009658836 cites W1969452223 @default.
- W2009658836 cites W1971980406 @default.
- W2009658836 cites W1976108074 @default.
- W2009658836 cites W1990967695 @default.
- W2009658836 cites W1996551329 @default.
- W2009658836 cites W1997301608 @default.
- W2009658836 cites W2010416554 @default.
- W2009658836 cites W2023178035 @default.
- W2009658836 cites W2036684049 @default.
- W2009658836 cites W2039887170 @default.
- W2009658836 cites W2045812196 @default.
- W2009658836 cites W2047681882 @default.
- W2009658836 cites W2079706694 @default.
- W2009658836 cites W2094739229 @default.
- W2009658836 cites W2105807625 @default.
- W2009658836 cites W2176697008 @default.
- W2009658836 cites W2345294145 @default.
- W2009658836 doi "https://doi.org/10.1006/bbrc.1998.8884" @default.
- W2009658836 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9647787" @default.
- W2009658836 hasPublicationYear "1998" @default.
- W2009658836 type Work @default.
- W2009658836 sameAs 2009658836 @default.
- W2009658836 citedByCount "12" @default.
- W2009658836 countsByYear W20096588362016 @default.
- W2009658836 countsByYear W20096588362017 @default.
- W2009658836 countsByYear W20096588362023 @default.
- W2009658836 crossrefType "journal-article" @default.
- W2009658836 hasAuthorship W2009658836A5017535959 @default.
- W2009658836 hasAuthorship W2009658836A5044168126 @default.
- W2009658836 hasAuthorship W2009658836A5054391481 @default.
- W2009658836 hasAuthorship W2009658836A5084878846 @default.
- W2009658836 hasConcept C101762097 @default.
- W2009658836 hasConcept C104317684 @default.
- W2009658836 hasConcept C107824862 @default.
- W2009658836 hasConcept C121608353 @default.
- W2009658836 hasConcept C150194340 @default.
- W2009658836 hasConcept C153911025 @default.
- W2009658836 hasConcept C179639408 @default.
- W2009658836 hasConcept C2778021871 @default.
- W2009658836 hasConcept C33987129 @default.
- W2009658836 hasConcept C51445715 @default.
- W2009658836 hasConcept C530470458 @default.
- W2009658836 hasConcept C54355233 @default.
- W2009658836 hasConcept C552990157 @default.
- W2009658836 hasConcept C55493867 @default.
- W2009658836 hasConcept C65888428 @default.
- W2009658836 hasConcept C84606932 @default.
- W2009658836 hasConcept C86339819 @default.
- W2009658836 hasConcept C86803240 @default.
- W2009658836 hasConceptScore W2009658836C101762097 @default.
- W2009658836 hasConceptScore W2009658836C104317684 @default.
- W2009658836 hasConceptScore W2009658836C107824862 @default.
- W2009658836 hasConceptScore W2009658836C121608353 @default.
- W2009658836 hasConceptScore W2009658836C150194340 @default.
- W2009658836 hasConceptScore W2009658836C153911025 @default.
- W2009658836 hasConceptScore W2009658836C179639408 @default.
- W2009658836 hasConceptScore W2009658836C2778021871 @default.
- W2009658836 hasConceptScore W2009658836C33987129 @default.
- W2009658836 hasConceptScore W2009658836C51445715 @default.
- W2009658836 hasConceptScore W2009658836C530470458 @default.
- W2009658836 hasConceptScore W2009658836C54355233 @default.
- W2009658836 hasConceptScore W2009658836C552990157 @default.
- W2009658836 hasConceptScore W2009658836C55493867 @default.
- W2009658836 hasConceptScore W2009658836C65888428 @default.
- W2009658836 hasConceptScore W2009658836C84606932 @default.
- W2009658836 hasConceptScore W2009658836C86339819 @default.
- W2009658836 hasConceptScore W2009658836C86803240 @default.
- W2009658836 hasLocation W20096588361 @default.
- W2009658836 hasLocation W20096588362 @default.
- W2009658836 hasOpenAccess W2009658836 @default.
- W2009658836 hasPrimaryLocation W20096588361 @default.
- W2009658836 hasRelatedWork W1486108356 @default.
- W2009658836 hasRelatedWork W1518056078 @default.
- W2009658836 hasRelatedWork W1519680626 @default.
- W2009658836 hasRelatedWork W2008452048 @default.
- W2009658836 hasRelatedWork W2009658836 @default.
- W2009658836 hasRelatedWork W2016009018 @default.
- W2009658836 hasRelatedWork W2037237395 @default.
- W2009658836 hasRelatedWork W2039836699 @default.
- W2009658836 hasRelatedWork W2071137639 @default.
- W2009658836 hasRelatedWork W2076362095 @default.
- W2009658836 isParatext "false" @default.
- W2009658836 isRetracted "false" @default.
- W2009658836 magId "2009658836" @default.
- W2009658836 workType "article" @default.