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- W2009665241 abstract "Lactobionic acid, a major constituent of a solution used to preserve organs prior to transplantation, can chelate ferric iron. This is evident by its ability to solubilize iron as well as changes that occur in the UV-VIS spectra of iron in its presence. Relative to iron (III) chelated to EDTA, the lactobionic acid-iron (III) complex is less able to participate in the Fenton reaction as measured by formaldehyde generation from DMSO and bleaching of p-N,N-dimethylnitrosoaniline. Similar effects are seen with citrate and ATP, two substances which also appear to be able to ameliorate ischemia/reperfusion injury. These findings present a rationale for the effectiveness of lactobionic acid as an organ preservant." @default.
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- W2009665241 date "1989-01-01" @default.
- W2009665241 modified "2023-10-18" @default.
- W2009665241 title "Lactobionic acid as an iron chelator: A rationale for its effectiveness as an organ preservant" @default.
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- W2009665241 doi "https://doi.org/10.1016/0024-3205(89)90120-3" @default.
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