FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009675488> ?p ?o ?g. }

• W2009675488 endingPage "2816" @default.
• W2009675488 startingPage "2811" @default.
• W2009675488 abstract "In patients with septic shock (n = 32), multitrauma (n = 8), and hospitalized matched controls (n = 41), we serially measured serum macrophage inhibitory factor (MIF), cortisol, plasma ACTH, tumor necrosis factor-α, and interleukin-6 (IL-6) immunoreactivity during 14 days or until discharge/death. MIF levels were significantly elevated on day 1 in septic shock (14.3 ± 4.5 μg/L), as opposed to trauma (3.1 ± 1.7 μg/L) and control patients (2.5 ± 2.1 μg/L). The time course of MIF, parallel to cortisol, but in contrast to ACTH, showed persistently elevated levels in septic patients. On admission, nonsurvivors of septic shock (n = 11) showed significantly higher MIF levels than survivors (18.4 ± 4.8 and 10.2 ± 4.2 μg/L, respectively). Patients with septic adult respiratory distress syndrome (ARDS; n = 8) showed higher MIF levels than those who did not develop ARDS (19.4 ± 4.7 vs. 9.2 ± 4.3 μg/L, respectively). Multiple logistic regression analysis demonstrated that both MIF and ARDS were independent predictors of adverse outcome. On admission, tumor necrosis factor-α, IL-6, procalcitonin, and lipopolysaccharide-binding protein levels were higher in patients with septic shock than in patients with multitrauma. In septic patients, regression analysis showed significant correlations between MIF and cortisol as well as between MIF and IL-6 levels and disease severity scores. No relation was found between MIF and markers of the acute phase response (procalcitonin, C- reactive protein, and lipopolysaccharide-binding protein). In multitrauma patients, MIF levels were not elevated at any time point and were not related to other variables. Our data suggest that during immune-mediated inflammation (such as septic shock) MIF is an important neuroendocrine mediator: a contraregulator of the immunosuppressive effects of glucocorticoids." @default.
• W2009675488 created "2016-06-24" @default.
• W2009675488 creator A5016328305 @default.
• W2009675488 creator A5036388936 @default.
• W2009675488 creator A5049037591 @default.
• W2009675488 creator A5073463366 @default.
• W2009675488 date "2001-06-01" @default.
• W2009675488 modified "2023-10-15" @default.
• W2009675488 title "Macrophage Migration Inhibitory Factor and Hypothalamo-Pituitary-Adrenal Function during Critical Illness" @default.
• W2009675488 cites W1510912973 @default.
• W2009675488 cites W1540323116 @default.
• W2009675488 cites W1573094840 @default.
• W2009675488 cites W1574734561 @default.
• W2009675488 cites W1642259399 @default.
• W2009675488 cites W1898928487 @default.
• W2009675488 cites W1922155627 @default.
• W2009675488 cites W1965778501 @default.
• W2009675488 cites W1967628584 @default.
• W2009675488 cites W1971885333 @default.
• W2009675488 cites W1975732582 @default.
• W2009675488 cites W1977176665 @default.
• W2009675488 cites W1981465100 @default.
• W2009675488 cites W1997325352 @default.
• W2009675488 cites W1998086688 @default.
• W2009675488 cites W2006839417 @default.
• W2009675488 cites W2008434501 @default.
• W2009675488 cites W2024977803 @default.
• W2009675488 cites W2031149131 @default.
• W2009675488 cites W2032439102 @default.
• W2009675488 cites W2033835426 @default.
• W2009675488 cites W2038328738 @default.
• W2009675488 cites W2040336985 @default.
• W2009675488 cites W2049679215 @default.
• W2009675488 cites W2056554475 @default.
• W2009675488 cites W2057418352 @default.
• W2009675488 cites W2062824264 @default.
• W2009675488 cites W2072002199 @default.
• W2009675488 cites W2076636961 @default.
• W2009675488 cites W2090056328 @default.
• W2009675488 cites W2122151701 @default.
• W2009675488 cites W2126600660 @default.
• W2009675488 cites W2132561351 @default.
• W2009675488 cites W2141991660 @default.
• W2009675488 cites W2142172638 @default.
• W2009675488 cites W2143305123 @default.
• W2009675488 cites W2146058212 @default.
• W2009675488 cites W2147383865 @default.
• W2009675488 cites W2152058417 @default.
• W2009675488 cites W2161328469 @default.
• W2009675488 cites W2182299927 @default.
• W2009675488 cites W2320349682 @default.
• W2009675488 cites W2342153330 @default.
• W2009675488 cites W4232746652 @default.
• W2009675488 cites W4293108385 @default.
• W2009675488 cites W4293242440 @default.
• W2009675488 cites W4313333663 @default.
• W2009675488 cites W46942126 @default.
• W2009675488 doi "https://doi.org/10.1210/jcem.86.6.7570" @default.
• W2009675488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11397892" @default.
• W2009675488 hasPublicationYear "2001" @default.
• W2009675488 type Work @default.
• W2009675488 sameAs 2009675488 @default.
• W2009675488 citedByCount "118" @default.
• W2009675488 countsByYear W20096754882012 @default.
• W2009675488 countsByYear W20096754882014 @default.
• W2009675488 countsByYear W20096754882015 @default.
• W2009675488 countsByYear W20096754882016 @default.
• W2009675488 countsByYear W20096754882018 @default.
• W2009675488 countsByYear W20096754882020 @default.
• W2009675488 countsByYear W20096754882021 @default.
• W2009675488 countsByYear W20096754882022 @default.
• W2009675488 countsByYear W20096754882023 @default.
• W2009675488 crossrefType "journal-article" @default.
• W2009675488 hasAuthorship W2009675488A5016328305 @default.
• W2009675488 hasAuthorship W2009675488A5036388936 @default.
• W2009675488 hasAuthorship W2009675488A5049037591 @default.
• W2009675488 hasAuthorship W2009675488A5073463366 @default.
• W2009675488 hasBestOaLocation W20096754881 @default.
• W2009675488 hasConcept C104177226 @default.
• W2009675488 hasConcept C10936531 @default.
• W2009675488 hasConcept C126322002 @default.
• W2009675488 hasConcept C134018914 @default.
• W2009675488 hasConcept C17991360 @default.
• W2009675488 hasConcept C203014093 @default.
• W2009675488 hasConcept C2776348555 @default.
• W2009675488 hasConcept C2777628635 @default.
• W2009675488 hasConcept C2777714996 @default.
• W2009675488 hasConcept C2778384902 @default.
• W2009675488 hasConcept C2778690821 @default.
• W2009675488 hasConcept C2778754761 @default.
• W2009675488 hasConcept C2781300812 @default.
• W2009675488 hasConcept C71924100 @default.
• W2009675488 hasConcept C90924648 @default.
• W2009675488 hasConceptScore W2009675488C104177226 @default.
• W2009675488 hasConceptScore W2009675488C10936531 @default.
• W2009675488 hasConceptScore W2009675488C126322002 @default.
• W2009675488 hasConceptScore W2009675488C134018914 @default.
• W2009675488 hasConceptScore W2009675488C17991360 @default.

• next