Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009678410> ?p ?o ?g. }
- W2009678410 endingPage "1034" @default.
- W2009678410 startingPage "1029" @default.
- W2009678410 abstract "The amino acid residues serine at position 213 (S213) and lysine at position 218 (K218), which are present in close proximity to the histidine-rich motif II of Mucor rouxii fatty acid Δ6-desaturase isoform II, were targeted for studying structure–function relationships using site-directed mutagenesis. The mutants were functionally characterized in a heterologous host, Saccharomyces cerevisiae. Substrate specificity and preference studies revealed that S213 and K218 are involved in substrate recognition. K218 plays a role in substrate preference by involvement in the binding of substrates, particularly C15–C18 monoene fatty acids. Modification of the M. rouxii Δ6-desaturase therefore has potential in specifically altering substrate utilization for production of desired fatty acids." @default.
- W2009678410 created "2016-06-24" @default.
- W2009678410 creator A5000807929 @default.
- W2009678410 creator A5002924322 @default.
- W2009678410 creator A5009654427 @default.
- W2009678410 creator A5010198217 @default.
- W2009678410 creator A5075797029 @default.
- W2009678410 date "2006-01-01" @default.
- W2009678410 modified "2023-10-18" @default.
- W2009678410 title "Targeted mutagenesis of a fatty acid Δ6-desaturase from Mucor rouxii: Role of amino acid residues adjacent to histidine-rich motif II" @default.
- W2009678410 cites W1501743111 @default.
- W2009678410 cites W1537575103 @default.
- W2009678410 cites W1966884806 @default.
- W2009678410 cites W1966991669 @default.
- W2009678410 cites W1970921900 @default.
- W2009678410 cites W1979094012 @default.
- W2009678410 cites W1990978381 @default.
- W2009678410 cites W1991283899 @default.
- W2009678410 cites W1994710856 @default.
- W2009678410 cites W1996689540 @default.
- W2009678410 cites W2000879566 @default.
- W2009678410 cites W2005290737 @default.
- W2009678410 cites W2007037143 @default.
- W2009678410 cites W2018423751 @default.
- W2009678410 cites W2055134264 @default.
- W2009678410 cites W2059268226 @default.
- W2009678410 cites W2088259501 @default.
- W2009678410 cites W2097870001 @default.
- W2009678410 cites W2111616120 @default.
- W2009678410 cites W2131225804 @default.
- W2009678410 cites W2141941210 @default.
- W2009678410 cites W2144665894 @default.
- W2009678410 cites W2152770371 @default.
- W2009678410 cites W2158906453 @default.
- W2009678410 cites W2159729794 @default.
- W2009678410 cites W2331207187 @default.
- W2009678410 cites W2407227766 @default.
- W2009678410 cites W2952186302 @default.
- W2009678410 cites W4321429334 @default.
- W2009678410 doi "https://doi.org/10.1016/j.bbrc.2005.11.115" @default.
- W2009678410 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16337147" @default.
- W2009678410 hasPublicationYear "2006" @default.
- W2009678410 type Work @default.
- W2009678410 sameAs 2009678410 @default.
- W2009678410 citedByCount "30" @default.
- W2009678410 countsByYear W20096784102013 @default.
- W2009678410 countsByYear W20096784102015 @default.
- W2009678410 countsByYear W20096784102016 @default.
- W2009678410 countsByYear W20096784102017 @default.
- W2009678410 countsByYear W20096784102018 @default.
- W2009678410 countsByYear W20096784102020 @default.
- W2009678410 countsByYear W20096784102022 @default.
- W2009678410 countsByYear W20096784102023 @default.
- W2009678410 crossrefType "journal-article" @default.
- W2009678410 hasAuthorship W2009678410A5000807929 @default.
- W2009678410 hasAuthorship W2009678410A5002924322 @default.
- W2009678410 hasAuthorship W2009678410A5009654427 @default.
- W2009678410 hasAuthorship W2009678410A5010198217 @default.
- W2009678410 hasAuthorship W2009678410A5075797029 @default.
- W2009678410 hasConcept C103408237 @default.
- W2009678410 hasConcept C104317684 @default.
- W2009678410 hasConcept C108305142 @default.
- W2009678410 hasConcept C143065580 @default.
- W2009678410 hasConcept C16318435 @default.
- W2009678410 hasConcept C181199279 @default.
- W2009678410 hasConcept C19038510 @default.
- W2009678410 hasConcept C2776016237 @default.
- W2009678410 hasConcept C2776414213 @default.
- W2009678410 hasConcept C2777129432 @default.
- W2009678410 hasConcept C2777576037 @default.
- W2009678410 hasConcept C2778460671 @default.
- W2009678410 hasConcept C2779222958 @default.
- W2009678410 hasConcept C2780115692 @default.
- W2009678410 hasConcept C40767141 @default.
- W2009678410 hasConcept C515207424 @default.
- W2009678410 hasConcept C543025807 @default.
- W2009678410 hasConcept C55493867 @default.
- W2009678410 hasConcept C86803240 @default.
- W2009678410 hasConceptScore W2009678410C103408237 @default.
- W2009678410 hasConceptScore W2009678410C104317684 @default.
- W2009678410 hasConceptScore W2009678410C108305142 @default.
- W2009678410 hasConceptScore W2009678410C143065580 @default.
- W2009678410 hasConceptScore W2009678410C16318435 @default.
- W2009678410 hasConceptScore W2009678410C181199279 @default.
- W2009678410 hasConceptScore W2009678410C19038510 @default.
- W2009678410 hasConceptScore W2009678410C2776016237 @default.
- W2009678410 hasConceptScore W2009678410C2776414213 @default.
- W2009678410 hasConceptScore W2009678410C2777129432 @default.
- W2009678410 hasConceptScore W2009678410C2777576037 @default.
- W2009678410 hasConceptScore W2009678410C2778460671 @default.
- W2009678410 hasConceptScore W2009678410C2779222958 @default.
- W2009678410 hasConceptScore W2009678410C2780115692 @default.
- W2009678410 hasConceptScore W2009678410C40767141 @default.
- W2009678410 hasConceptScore W2009678410C515207424 @default.
- W2009678410 hasConceptScore W2009678410C543025807 @default.
- W2009678410 hasConceptScore W2009678410C55493867 @default.
- W2009678410 hasConceptScore W2009678410C86803240 @default.
- W2009678410 hasIssue "4" @default.