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- W2009696320 abstract "The total fibrous and nonfibrous mineral content of the lung has been analyzed in a series of 14 men with lung cancer but no history of occupational dust exposure, and in a series of 14 control men matched for age, smoking history, and general occupational class. The lung cancer patients had an average of 525 ± 369 × 106 exogenous mineral particles and 17.4 ± 19.6 × 106 exogenous mineral fibers/g dry lung, while the controls had averages of 261 ± 175 mineral particles and 4.7 ± 3.2 × 106 mineral fibers/g dry lung. These differences are statistically significant for both particles and fibers. Kaolinite, talc, mica, feldspars, and crystalline silica comprised the majority of particles of both groups. Approximately 90% of the particles were smaller than 2 μm in diameter and approximately 60% smaller than 1 μm; the mean particle size in the cancer group was 1.1 ± 0.2 μm and in the control group 1.3 ± 0.2 μm. In both groups, patients who had smoked more than 35 pack years had greater numbers of particles than patients who had smoked less than 35 pack years. It is concluded that, in this study, lungs from patients with lung cancer had statistically greater numbers of mineral particles and fibers than lungs from controls, and that smoking influences total long-term retention of particles from all sources." @default.
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- W2009696320 title "Mineral particles, mineral fibers, and lung cancer" @default.
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- W2009696320 doi "https://doi.org/10.1016/0013-9351(85)90117-3" @default.
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