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- W2009697321 abstract "Abstract We have previously reported that an RNA polymerase mutation, rif R 2, of Escherichia coli retards T4 bacteriophage development. The effect of rif R 2 on phage production is partially suppressed in β-glucosyl transferaseless mutants of T4 and β-glucosylation of the parental DNA alone is sufficient to inhibit phage growth. Both physiological studies and the map positions of other suppressing T4 mutations (in genes 45 and maybe 55) support the conclusion that there are two effects of rif R 2 during phage development: a direct effect on T4 DNA replication and a direct effect on late gene expression. Both of these defects seem in part to be due to a failure of the mutant RNA polymerase to perform a reaction(s) which physically alters or changes the association of parental and then, probably, some progeny DNA. This reaction is required early for T4 DNA replication and throughout infection for late gene expression." @default.
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- W2009697321 title "Inhibition of T4 growth by an RNA polymerase mutation of Escherichia coli: Physiological and genetic analysis of the effects during phage development" @default.
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- W2009697321 doi "https://doi.org/10.1016/0042-6822(74)90314-6" @default.
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