Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009711282> ?p ?o ?g. }
- W2009711282 endingPage "3210" @default.
- W2009711282 startingPage "3208" @default.
- W2009711282 abstract "An efficient synthesis of the influenza neuraminidase inhibitor prodrug oseltamivir phosphate (Tamiflu) from cheap, commercially available d-ribose is described. The main features of this approach comprise a metal (Zn, In)-mediated domino reaction and ring-closing olefin metathesis (RCM) of the resultant functionalized dienes to produce the Tamiflu skeleton. The synthesis described in this Letter represents a new and efficient transformation of a shikimic acid derivative into a 1,2-diamino compound which involved oxidation of an alcohol followed by reductive amination, regioselective ring opening of an amino pentylidene ketal and stereospecific nucleophilic replacement of a triflate with an azide." @default.
- W2009711282 created "2016-06-24" @default.
- W2009711282 creator A5001128188 @default.
- W2009711282 creator A5019983381 @default.
- W2009711282 creator A5039198891 @default.
- W2009711282 creator A5070870587 @default.
- W2009711282 date "2010-06-01" @default.
- W2009711282 modified "2023-10-18" @default.
- W2009711282 title "An efficient synthesis of oseltamivir phosphate (Tamiflu) via a metal-mediated domino reaction and ring-closing metathesis" @default.
- W2009711282 cites W1967552265 @default.
- W2009711282 cites W1969943225 @default.
- W2009711282 cites W2003926950 @default.
- W2009711282 cites W2016827090 @default.
- W2009711282 cites W2017807106 @default.
- W2009711282 cites W2028497074 @default.
- W2009711282 cites W2044032836 @default.
- W2009711282 cites W2065333251 @default.
- W2009711282 cites W2068133035 @default.
- W2009711282 cites W2076322535 @default.
- W2009711282 cites W2084838002 @default.
- W2009711282 cites W2093232968 @default.
- W2009711282 cites W2108889603 @default.
- W2009711282 cites W2149989693 @default.
- W2009711282 cites W2949524476 @default.
- W2009711282 doi "https://doi.org/10.1016/j.tetlet.2010.04.044" @default.
- W2009711282 hasPublicationYear "2010" @default.
- W2009711282 type Work @default.
- W2009711282 sameAs 2009711282 @default.
- W2009711282 citedByCount "34" @default.
- W2009711282 countsByYear W20097112822012 @default.
- W2009711282 countsByYear W20097112822013 @default.
- W2009711282 countsByYear W20097112822014 @default.
- W2009711282 countsByYear W20097112822015 @default.
- W2009711282 countsByYear W20097112822016 @default.
- W2009711282 countsByYear W20097112822017 @default.
- W2009711282 countsByYear W20097112822018 @default.
- W2009711282 countsByYear W20097112822019 @default.
- W2009711282 countsByYear W20097112822020 @default.
- W2009711282 countsByYear W20097112822023 @default.
- W2009711282 crossrefType "journal-article" @default.
- W2009711282 hasAuthorship W2009711282A5001128188 @default.
- W2009711282 hasAuthorship W2009711282A5019983381 @default.
- W2009711282 hasAuthorship W2009711282A5039198891 @default.
- W2009711282 hasAuthorship W2009711282A5070870587 @default.
- W2009711282 hasConcept C153914509 @default.
- W2009711282 hasConcept C155647269 @default.
- W2009711282 hasConcept C161790260 @default.
- W2009711282 hasConcept C178790620 @default.
- W2009711282 hasConcept C178907741 @default.
- W2009711282 hasConcept C185592680 @default.
- W2009711282 hasConcept C21774173 @default.
- W2009711282 hasConcept C21951064 @default.
- W2009711282 hasConcept C2776416436 @default.
- W2009711282 hasConcept C2778544067 @default.
- W2009711282 hasConcept C2778593322 @default.
- W2009711282 hasConcept C2778656812 @default.
- W2009711282 hasConcept C2780378348 @default.
- W2009711282 hasConcept C40875361 @default.
- W2009711282 hasConcept C44138296 @default.
- W2009711282 hasConcept C44228677 @default.
- W2009711282 hasConcept C521977710 @default.
- W2009711282 hasConcept C59759590 @default.
- W2009711282 hasConceptScore W2009711282C153914509 @default.
- W2009711282 hasConceptScore W2009711282C155647269 @default.
- W2009711282 hasConceptScore W2009711282C161790260 @default.
- W2009711282 hasConceptScore W2009711282C178790620 @default.
- W2009711282 hasConceptScore W2009711282C178907741 @default.
- W2009711282 hasConceptScore W2009711282C185592680 @default.
- W2009711282 hasConceptScore W2009711282C21774173 @default.
- W2009711282 hasConceptScore W2009711282C21951064 @default.
- W2009711282 hasConceptScore W2009711282C2776416436 @default.
- W2009711282 hasConceptScore W2009711282C2778544067 @default.
- W2009711282 hasConceptScore W2009711282C2778593322 @default.
- W2009711282 hasConceptScore W2009711282C2778656812 @default.
- W2009711282 hasConceptScore W2009711282C2780378348 @default.
- W2009711282 hasConceptScore W2009711282C40875361 @default.
- W2009711282 hasConceptScore W2009711282C44138296 @default.
- W2009711282 hasConceptScore W2009711282C44228677 @default.
- W2009711282 hasConceptScore W2009711282C521977710 @default.
- W2009711282 hasConceptScore W2009711282C59759590 @default.
- W2009711282 hasIssue "24" @default.
- W2009711282 hasLocation W20097112821 @default.
- W2009711282 hasOpenAccess W2009711282 @default.
- W2009711282 hasPrimaryLocation W20097112821 @default.
- W2009711282 hasRelatedWork W1964867985 @default.
- W2009711282 hasRelatedWork W1989797305 @default.
- W2009711282 hasRelatedWork W2009711282 @default.
- W2009711282 hasRelatedWork W2041909595 @default.
- W2009711282 hasRelatedWork W2089041385 @default.
- W2009711282 hasRelatedWork W2109387561 @default.
- W2009711282 hasRelatedWork W2329348246 @default.
- W2009711282 hasRelatedWork W2756990246 @default.
- W2009711282 hasRelatedWork W2949949447 @default.
- W2009711282 hasRelatedWork W2952178389 @default.
- W2009711282 hasVolume "51" @default.
- W2009711282 isParatext "false" @default.
- W2009711282 isRetracted "false" @default.
- W2009711282 magId "2009711282" @default.