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- W2009715778 abstract "The Sfh protein is encoded by self-transmissible plasmids involved in human typhoid and is closely related to the global regulator H-NS. We have found that Sfh provides a stealth function that allows the plasmids to be transmitted to new bacterial hosts with minimal effects on their fitness. Introducing the plasmid without the sfh gene imposes a mild H-NS – phenotype and a severe loss of fitness due to titration of the cellular pool of H-NS by the A+T-rich plasmid. This stealth strategy seems to be used widely to aid horizontal DNA transmission and has important implications for bacterial evolution." @default.
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- W2009715778 date "2007-01-12" @default.
- W2009715778 modified "2023-10-18" @default.
- W2009715778 title "An H-NS-like Stealth Protein Aids Horizontal DNA Transmission in Bacteria" @default.
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- W2009715778 doi "https://doi.org/10.1126/science.1137550" @default.
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