Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009719328> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2009719328 endingPage "158" @default.
- W2009719328 startingPage "153" @default.
- W2009719328 abstract "Staufen1 (Stau1), a host cellular protein, along with non-structural protein 1 (NS1), an influenza viral protein, associate with each other during influenza viral infection and down-regulation of Stau1 by RNA interference reduces the yield of influenza A virus, suggesting a role for Stau1 in viral replication. In order to develop a new tool to control influenza A virus, we determined the specific regions of Staufen1 protein involved in the interaction with NS1. The linker between RBD3 and 4 was isolated as the binding regions. Expression of RBD3L, the linker including RBD3, inhibited the interaction between Stau1 and NS1, reducing the colocalization of the two proteins in the cytosol and nucleus regions. In addition, yield of influenza A virus in RBD3L-expressing cells was significantly reduced 36 h after infection. These results suggest that disruption of the Stau1-NS1 interaction can be used to control replication of influenza A virus, thereby providing a target for the development of antiviral drugs." @default.
- W2009719328 created "2016-06-24" @default.
- W2009719328 creator A5014501054 @default.
- W2009719328 creator A5021061898 @default.
- W2009719328 creator A5041100734 @default.
- W2009719328 creator A5063718262 @default.
- W2009719328 creator A5063790988 @default.
- W2009719328 creator A5085375647 @default.
- W2009719328 date "2011-10-01" @default.
- W2009719328 modified "2023-09-27" @default.
- W2009719328 title "Impairment of the Staufen1-NS1 interaction reduces influenza viral replication" @default.
- W2009719328 cites W1976407358 @default.
- W2009719328 cites W1988581728 @default.
- W2009719328 cites W1997408440 @default.
- W2009719328 cites W2001644877 @default.
- W2009719328 cites W2032005329 @default.
- W2009719328 cites W2039483481 @default.
- W2009719328 cites W2056080643 @default.
- W2009719328 cites W2058596298 @default.
- W2009719328 cites W2070924692 @default.
- W2009719328 cites W2074410038 @default.
- W2009719328 cites W2076347860 @default.
- W2009719328 cites W2079828909 @default.
- W2009719328 cites W2106525727 @default.
- W2009719328 cites W2107777962 @default.
- W2009719328 cites W2110214166 @default.
- W2009719328 cites W2111471117 @default.
- W2009719328 cites W2116438422 @default.
- W2009719328 cites W2118752962 @default.
- W2009719328 cites W2119752891 @default.
- W2009719328 cites W2145691034 @default.
- W2009719328 cites W2151587699 @default.
- W2009719328 cites W2156664602 @default.
- W2009719328 cites W2157177671 @default.
- W2009719328 cites W2160103276 @default.
- W2009719328 cites W2162592749 @default.
- W2009719328 cites W2168621505 @default.
- W2009719328 cites W4237959566 @default.
- W2009719328 cites W4256110274 @default.
- W2009719328 doi "https://doi.org/10.1016/j.bbrc.2011.09.042" @default.
- W2009719328 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21945618" @default.
- W2009719328 hasPublicationYear "2011" @default.
- W2009719328 type Work @default.
- W2009719328 sameAs 2009719328 @default.
- W2009719328 citedByCount "13" @default.
- W2009719328 countsByYear W20097193282013 @default.
- W2009719328 countsByYear W20097193282016 @default.
- W2009719328 countsByYear W20097193282018 @default.
- W2009719328 countsByYear W20097193282020 @default.
- W2009719328 countsByYear W20097193282021 @default.
- W2009719328 countsByYear W20097193282022 @default.
- W2009719328 crossrefType "journal-article" @default.
- W2009719328 hasAuthorship W2009719328A5014501054 @default.
- W2009719328 hasAuthorship W2009719328A5021061898 @default.
- W2009719328 hasAuthorship W2009719328A5041100734 @default.
- W2009719328 hasAuthorship W2009719328A5063718262 @default.
- W2009719328 hasAuthorship W2009719328A5063790988 @default.
- W2009719328 hasAuthorship W2009719328A5085375647 @default.
- W2009719328 hasConcept C140704245 @default.
- W2009719328 hasConcept C159047783 @default.
- W2009719328 hasConcept C2522874641 @default.
- W2009719328 hasConcept C2777546802 @default.
- W2009719328 hasConcept C68434959 @default.
- W2009719328 hasConcept C86803240 @default.
- W2009719328 hasConcept C95444343 @default.
- W2009719328 hasConceptScore W2009719328C140704245 @default.
- W2009719328 hasConceptScore W2009719328C159047783 @default.
- W2009719328 hasConceptScore W2009719328C2522874641 @default.
- W2009719328 hasConceptScore W2009719328C2777546802 @default.
- W2009719328 hasConceptScore W2009719328C68434959 @default.
- W2009719328 hasConceptScore W2009719328C86803240 @default.
- W2009719328 hasConceptScore W2009719328C95444343 @default.
- W2009719328 hasIssue "1" @default.
- W2009719328 hasLocation W20097193281 @default.
- W2009719328 hasLocation W20097193282 @default.
- W2009719328 hasOpenAccess W2009719328 @default.
- W2009719328 hasPrimaryLocation W20097193281 @default.
- W2009719328 hasRelatedWork W1572227522 @default.
- W2009719328 hasRelatedWork W2036413119 @default.
- W2009719328 hasRelatedWork W2107663516 @default.
- W2009719328 hasRelatedWork W2130654686 @default.
- W2009719328 hasRelatedWork W2148114753 @default.
- W2009719328 hasRelatedWork W2605056859 @default.
- W2009719328 hasRelatedWork W2613621187 @default.
- W2009719328 hasRelatedWork W2992274268 @default.
- W2009719328 hasRelatedWork W3165029026 @default.
- W2009719328 hasRelatedWork W4248770357 @default.
- W2009719328 hasVolume "414" @default.
- W2009719328 isParatext "false" @default.
- W2009719328 isRetracted "false" @default.
- W2009719328 magId "2009719328" @default.
- W2009719328 workType "article" @default.