FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009721804> ?p ?o ?g. }

• W2009721804 endingPage "2774" @default.
• W2009721804 startingPage "2765" @default.
• W2009721804 abstract "In order to investigate whether and how a modification of mitochondrial metabolism can affect yeast sensitivity to programmed cell death (PCD) induced by acetic acid (AA-PCD), yeast cells were grown on raffinose, as a sole carbon source, which, differently from glucose, favours mitochondrial respiration. We found that, differently from glucose-grown cells, raffinose-grown cells were mostly resistant to AA-PCD and that this was due to the activation of mitochondrial retrograde (RTG) response, which increased with time, as revealed by the up-regulation of the peroxisomal isoform of citrate synthase and isocitrate dehydrogenase isoform 1, RTG pathway target genes. Accordingly, the deletion of RTG2 and RTG3, a positive regulator and a transcription factor of the RTG pathway, resulted in AA-PCD, as shown by TUNEL assay. Neither deletion in raffinose-grown cells of HAP4, encoding the positive regulatory subunit of the Hap2,3,4,5 complex nor constitutive activation of the RTG pathway in glucose-grown cells due to deletion of MKS1, a negative regulator of RTG pathway, had effect on yeast AA-PCD. The RTG pathway was found to be activated in yeast cells containing mitochondria, in which membrane potential was measured, capable to consume oxygen in a manner stimulated by the uncoupler CCCP and inhibited by the respiratory chain inhibitor antimycin A. AA-PCD resistance in raffinose-grown cells occurs with a decrease in both ROS production and cytochrome c release as compared to glucose-grown cells en route to AA-PCD." @default.
• W2009721804 created "2016-06-24" @default.
• W2009721804 creator A5020805217 @default.
• W2009721804 creator A5021418009 @default.
• W2009721804 creator A5025651455 @default.
• W2009721804 creator A5033599316 @default.
• W2009721804 creator A5036316489 @default.
• W2009721804 creator A5036681307 @default.
• W2009721804 creator A5039933465 @default.
• W2009721804 creator A5055428629 @default.
• W2009721804 creator A5057064812 @default.
• W2009721804 date "2013-12-01" @default.
• W2009721804 modified "2023-09-28" @default.
• W2009721804 title "Yeast growth in raffinose results in resistance to acetic-acid induced programmed cell death mostly due to the activation of the mitochondrial retrograde pathway" @default.
• W2009721804 cites W1548851567 @default.
• W2009721804 cites W1585360791 @default.
• W2009721804 cites W183042769 @default.
• W2009721804 cites W1879890282 @default.
• W2009721804 cites W1902096350 @default.
• W2009721804 cites W1974545455 @default.
• W2009721804 cites W1978423374 @default.
• W2009721804 cites W1983741377 @default.
• W2009721804 cites W1991846448 @default.
• W2009721804 cites W1994464660 @default.
• W2009721804 cites W1999207195 @default.
• W2009721804 cites W2000898610 @default.
• W2009721804 cites W2001534373 @default.
• W2009721804 cites W2003822984 @default.
• W2009721804 cites W2005595886 @default.
• W2009721804 cites W2006985224 @default.
• W2009721804 cites W2010730552 @default.
• W2009721804 cites W2023003671 @default.
• W2009721804 cites W2025873104 @default.
• W2009721804 cites W2026514003 @default.
• W2009721804 cites W2030293206 @default.
• W2009721804 cites W2034608089 @default.
• W2009721804 cites W2039348210 @default.
• W2009721804 cites W2040659239 @default.
• W2009721804 cites W2049547722 @default.
• W2009721804 cites W2050374206 @default.
• W2009721804 cites W2050811403 @default.
• W2009721804 cites W2059382856 @default.
• W2009721804 cites W2081827055 @default.
• W2009721804 cites W2082918093 @default.
• W2009721804 cites W2089219060 @default.
• W2009721804 cites W2089663038 @default.
• W2009721804 cites W2090095688 @default.
• W2009721804 cites W2091296592 @default.
• W2009721804 cites W2095200464 @default.
• W2009721804 cites W2102284511 @default.
• W2009721804 cites W2108836442 @default.
• W2009721804 cites W2114721511 @default.
• W2009721804 cites W2117692326 @default.
• W2009721804 cites W2117905612 @default.
• W2009721804 cites W2119090089 @default.
• W2009721804 cites W2125198366 @default.
• W2009721804 cites W2128387695 @default.
• W2009721804 cites W2137119150 @default.
• W2009721804 cites W2138092588 @default.
• W2009721804 cites W2138845203 @default.
• W2009721804 cites W2140190579 @default.
• W2009721804 cites W2146875556 @default.
• W2009721804 cites W2152793164 @default.
• W2009721804 cites W2158475521 @default.
• W2009721804 cites W2160031507 @default.
• W2009721804 cites W2164875113 @default.
• W2009721804 cites W2166470639 @default.
• W2009721804 cites W2168140776 @default.
• W2009721804 cites W2169423549 @default.
• W2009721804 cites W2169875902 @default.
• W2009721804 cites W2326129438 @default.
• W2009721804 cites W2328338738 @default.
• W2009721804 cites W4293247451 @default.
• W2009721804 cites W2085937061 @default.
• W2009721804 doi "https://doi.org/10.1016/j.bbamcr.2013.07.017" @default.
• W2009721804 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23906793" @default.
• W2009721804 hasPublicationYear "2013" @default.
• W2009721804 type Work @default.
• W2009721804 sameAs 2009721804 @default.
• W2009721804 citedByCount "34" @default.
• W2009721804 countsByYear W20097218042014 @default.
• W2009721804 countsByYear W20097218042015 @default.
• W2009721804 countsByYear W20097218042016 @default.
• W2009721804 countsByYear W20097218042017 @default.
• W2009721804 countsByYear W20097218042018 @default.
• W2009721804 countsByYear W20097218042019 @default.
• W2009721804 countsByYear W20097218042020 @default.
• W2009721804 countsByYear W20097218042021 @default.
• W2009721804 countsByYear W20097218042022 @default.
• W2009721804 countsByYear W20097218042023 @default.
• W2009721804 crossrefType "journal-article" @default.
• W2009721804 hasAuthorship W2009721804A5020805217 @default.
• W2009721804 hasAuthorship W2009721804A5021418009 @default.
• W2009721804 hasAuthorship W2009721804A5025651455 @default.
• W2009721804 hasAuthorship W2009721804A5033599316 @default.
• W2009721804 hasAuthorship W2009721804A5036316489 @default.
• W2009721804 hasAuthorship W2009721804A5036681307 @default.
• W2009721804 hasAuthorship W2009721804A5039933465 @default.

• next