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- W2009728428 abstract "Accommodation refers to the acquired resistance of a graft to immune-mediated injury. It is typically observed after antibodies that would cause rejection of a graft are removed from a recipient and then later return. In addition to being induced in this manner, accommodation can occur spontaneously, without depleting antibodies. Indeed, we postulate spontaneous accommodation may be the most common outcome of clinical organ transplantation. The paper reviews the current understanding of accommodation, emphasizing recent advances and important questions. Among the recent advances are the discoveries of potentially broader relevance of accommodation for biology and immunology and pathways by which accommodation may be achieved. To investigate these pathways and to understand how accommodation begins and how it evolves, clinical organ transplants might offer a useful and incisive model." @default.
- W2009728428 created "2016-06-24" @default.
- W2009728428 creator A5001576573 @default.
- W2009728428 creator A5012087578 @default.
- W2009728428 date "2007-08-01" @default.
- W2009728428 modified "2023-09-23" @default.
- W2009728428 title "Accommodation of grafts: Implications for health and disease" @default.
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- W2009728428 doi "https://doi.org/10.1016/j.humimm.2007.04.003" @default.
- W2009728428 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2703470" @default.
- W2009728428 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17678718" @default.
- W2009728428 hasPublicationYear "2007" @default.
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