Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009808657> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2009808657 endingPage "615" @default.
- W2009808657 startingPage "613" @default.
- W2009808657 abstract "Renal involvement occurs in 1%-12% in juvenile systemic sclerosis (JSSc) patients, mainly with arterial hypertension, proteinuria and scleroderma renal crisis. We report herein a patient who presented nephrotic syndrome (NS) as the first manifestation of JSSc with focal segmental glomerulosclerosis (FSGS). A female patient presented steroid-sensitive NS at the age of 12 years. At 14 years, she had orbital and lower limbs edema, arterial hypertension, sclerodactyly and proximal skin sclerosis. Moderate capillary dilation and mild focal devascularization were observed in nailfold capillaroscopy, compatible with early stage of scleroderma (scleroderma pattern). Percutaneous renal biopsy guided by ultrasound revealed focal segmental glomerulosclerosis and direct immunofluorescence were negative. Therefore, she fullfilled the provisional classification criteria for JSSc. Patient was treated with oral 25-hydroxyvitamin D (800 IU/day), methotrexate (0.5mg/kg/week) and amlodipin (0.15 mg/kg). Prednisone (60 mg/m2/day) was administered for 4 consecutive weeks, followed by alternate-day (40mg/m2) for 2 consecutive months, with tapering for 4 months and then stopping this medication. Currently she is being treated with methotrexate 15 mg/week, without edema and proteinuria. In conclusion, we reported a rare case of NS with FSGS as the first manifestation of scleroderma. Therefore, renal biopsy is mandatory in JSSc patients with sustained proteinuria or NS." @default.
- W2009808657 created "2016-06-24" @default.
- W2009808657 creator A5005943646 @default.
- W2009808657 creator A5015977988 @default.
- W2009808657 creator A5028461797 @default.
- W2009808657 creator A5048491343 @default.
- W2009808657 creator A5067957263 @default.
- W2009808657 creator A5086747860 @default.
- W2009808657 date "2017-11-01" @default.
- W2009808657 modified "2023-09-27" @default.
- W2009808657 title "Nephrotic syndrome as the first manifestation of juvenile systemic scleroderma" @default.
- W2009808657 cites W176618316 @default.
- W2009808657 cites W1808798629 @default.
- W2009808657 cites W205320079 @default.
- W2009808657 cites W2055911711 @default.
- W2009808657 cites W2060296628 @default.
- W2009808657 cites W2087434766 @default.
- W2009808657 cites W2093885269 @default.
- W2009808657 cites W2101767471 @default.
- W2009808657 cites W2121698048 @default.
- W2009808657 cites W2135869738 @default.
- W2009808657 cites W2149389714 @default.
- W2009808657 cites W2162364414 @default.
- W2009808657 cites W2163543028 @default.
- W2009808657 cites W2319083449 @default.
- W2009808657 doi "https://doi.org/10.1016/j.rbre.2014.08.004" @default.
- W2009808657 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29173697" @default.
- W2009808657 hasPublicationYear "2017" @default.
- W2009808657 type Work @default.
- W2009808657 sameAs 2009808657 @default.
- W2009808657 citedByCount "1" @default.
- W2009808657 countsByYear W20098086572017 @default.
- W2009808657 crossrefType "journal-article" @default.
- W2009808657 hasAuthorship W2009808657A5005943646 @default.
- W2009808657 hasAuthorship W2009808657A5015977988 @default.
- W2009808657 hasAuthorship W2009808657A5028461797 @default.
- W2009808657 hasAuthorship W2009808657A5048491343 @default.
- W2009808657 hasAuthorship W2009808657A5067957263 @default.
- W2009808657 hasAuthorship W2009808657A5086747860 @default.
- W2009808657 hasBestOaLocation W20098086571 @default.
- W2009808657 hasConcept C115961737 @default.
- W2009808657 hasConcept C126322002 @default.
- W2009808657 hasConcept C142724271 @default.
- W2009808657 hasConcept C16005928 @default.
- W2009808657 hasConcept C180032290 @default.
- W2009808657 hasConcept C2778751314 @default.
- W2009808657 hasConcept C2778930706 @default.
- W2009808657 hasConcept C2779625490 @default.
- W2009808657 hasConcept C2779967694 @default.
- W2009808657 hasConcept C54355233 @default.
- W2009808657 hasConcept C71924100 @default.
- W2009808657 hasConcept C86803240 @default.
- W2009808657 hasConceptScore W2009808657C115961737 @default.
- W2009808657 hasConceptScore W2009808657C126322002 @default.
- W2009808657 hasConceptScore W2009808657C142724271 @default.
- W2009808657 hasConceptScore W2009808657C16005928 @default.
- W2009808657 hasConceptScore W2009808657C180032290 @default.
- W2009808657 hasConceptScore W2009808657C2778751314 @default.
- W2009808657 hasConceptScore W2009808657C2778930706 @default.
- W2009808657 hasConceptScore W2009808657C2779625490 @default.
- W2009808657 hasConceptScore W2009808657C2779967694 @default.
- W2009808657 hasConceptScore W2009808657C54355233 @default.
- W2009808657 hasConceptScore W2009808657C71924100 @default.
- W2009808657 hasConceptScore W2009808657C86803240 @default.
- W2009808657 hasIssue "6" @default.
- W2009808657 hasLocation W20098086571 @default.
- W2009808657 hasLocation W20098086572 @default.
- W2009808657 hasLocation W20098086573 @default.
- W2009808657 hasLocation W20098086574 @default.
- W2009808657 hasLocation W20098086575 @default.
- W2009808657 hasOpenAccess W2009808657 @default.
- W2009808657 hasPrimaryLocation W20098086571 @default.
- W2009808657 hasRelatedWork W1977299683 @default.
- W2009808657 hasRelatedWork W2413594086 @default.
- W2009808657 hasRelatedWork W2461553664 @default.
- W2009808657 hasRelatedWork W2890230268 @default.
- W2009808657 hasRelatedWork W2923420417 @default.
- W2009808657 hasRelatedWork W2988911658 @default.
- W2009808657 hasRelatedWork W3196377230 @default.
- W2009808657 hasRelatedWork W3198230743 @default.
- W2009808657 hasRelatedWork W4234833016 @default.
- W2009808657 hasRelatedWork W46229524 @default.
- W2009808657 hasVolume "57" @default.
- W2009808657 isParatext "false" @default.
- W2009808657 isRetracted "false" @default.
- W2009808657 magId "2009808657" @default.
- W2009808657 workType "article" @default.