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- W2009840706 abstract "We describe a novel method, termed “pseudo-neutral-loss scan” MS, for selectively probing phosphopeptides and glycopeptides on a LTQ-Orbitrap mass spectrometer. The instrument has been programmed such that an in-source CID energy is applied to all species that eluted from LC column and were subsequently ionised in the electrospray ion source. Ion pairs that differ in the mass of a neutral loss of phosphoric acid or monosaccharide residues are automatically selected for CID MS/MS and further for multi-stage-activation MS3. Our method should prove useful for a highly selective and sensitive approach to identify phosphopeptides and glycopeptides from purified protein digestion without any further enrichment, and could potentially be of use in more complex mixture." @default.
- W2009840706 created "2016-06-24" @default.
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- W2009840706 date "2010-10-05" @default.
- W2009840706 modified "2023-10-16" @default.
- W2009840706 title "Pseudo-neutral-loss scan for selective detection of phosphopeptides and N-glycopeptides using liquid chromatography coupled with a hybrid linear ion-trap/orbitrap mass spectrometer" @default.
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- W2009840706 doi "https://doi.org/10.1002/pmic.201000290" @default.
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