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- W2009849587 abstract "Objective: To describe an extreme presentation of the chylomicronemia syndrome resulting in multiorgan system dysfunction. Patient: A 40-year-old African American male with no past medical history presented with multiorgan system dysfunction manifested by acute respiratory failure and acute kidney injury. He was noted to have very-high triglyceride levels (>5000 mg/dL) at admission. Interventions: An echocardiogram showed normal cardiac function. Amylase and lipase were normal. We confirmed the chylomicronemia syndrome with a triglyceride assay. The associated hyperviscosity was treated with plasmapheresis to reduce the plasma triglyceride level. Results: After 3 sessions of plasmapheresis, his triglyceride levels were significantly reduced, his oxygenation improved, and his acute kidney injury resolved. He was successfully extubated on day 7 of the intensive care unit stay. His diabetes and hypertriglyceridemia were newly diagnosed and drug therapy was instituted with home discharge on day 14. Conclusions: Severe chylomicronemia can cause multiorgan system dysfunction related to hyperviscosity. Early institution of plasmapheresis to reduce the triglyceride-rich lipoproteins can improve tissue perfusion and prevent further organ damage." @default.
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- W2009849587 date "2013-01-29" @default.
- W2009849587 modified "2023-09-26" @default.
- W2009849587 title "Multiorgan System Dysfunction in the Chylomicronemia Syndrome" @default.
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- W2009849587 doi "https://doi.org/10.1177/0885066613475425" @default.
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