Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009849608> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2009849608 endingPage "92" @default.
- W2009849608 startingPage "86" @default.
- W2009849608 abstract "The stimulation by cyclic AMP of steroidogenesis in rat adrenal cells isolated by trypsin treatment was inhibited by d-threo-chloram phenicol and by its l-threo-isomer. The former is an inhibitor of mitochondrial protein synthesis while the latter is not. Both substances, at concentrations which inhibit steroidogenesis, inhibit amino acid incorporation into the proteins of microsomes. Inhibition in other subcellular fractions also occurs depending on the isomer and its concentration. In no case was there a preferential inhibition of amino acid incorporation into mitochondrial proteins. Carbomycin, another inhibitor of mitochondrial protein synthesis, gave similar results. In addition, subfractionation of mitochondria in these experiments revealed no preferential inhibition of amino acid incorporation into the proteins of either the soluble or membrane fractions of this organelle. The above results were obtained at several concentrations of the inhibitors when only partial inhibition of steroidogenesis was present. Both isomers of chloramphenicol inhibited steroidogenesis in a cell-free system to an extent equal to that found with cyclic AMP-stimulated steroidogenesis in intact cells. It is concluded that these inhibitors of mitochondrial protein synthesis have multiple metabolic effects in adrenal cells." @default.
- W2009849608 created "2016-06-24" @default.
- W2009849608 creator A5004982119 @default.
- W2009849608 creator A5053024250 @default.
- W2009849608 date "1975-02-01" @default.
- W2009849608 modified "2023-09-26" @default.
- W2009849608 title "Mitochondrial protein synthesis and the stimulation of steroidogenesis by cyclic adenosine 3′,5′-monophosphate in isolated rat adrenal cells" @default.
- W2009849608 cites W1495959275 @default.
- W2009849608 cites W1500558125 @default.
- W2009849608 cites W1564498971 @default.
- W2009849608 cites W1578908619 @default.
- W2009849608 cites W1597737593 @default.
- W2009849608 cites W1750800863 @default.
- W2009849608 cites W1775749144 @default.
- W2009849608 cites W179357761 @default.
- W2009849608 cites W1967328275 @default.
- W2009849608 cites W1970502061 @default.
- W2009849608 cites W1983798063 @default.
- W2009849608 cites W1986231643 @default.
- W2009849608 cites W1997821178 @default.
- W2009849608 cites W2002414215 @default.
- W2009849608 cites W2012190938 @default.
- W2009849608 cites W2027032504 @default.
- W2009849608 cites W2052263538 @default.
- W2009849608 cites W2057529735 @default.
- W2009849608 cites W2060492670 @default.
- W2009849608 cites W2082250476 @default.
- W2009849608 cites W2091830473 @default.
- W2009849608 cites W2125462564 @default.
- W2009849608 cites W2138142730 @default.
- W2009849608 cites W3200073855 @default.
- W2009849608 cites W4246461710 @default.
- W2009849608 cites W97593476 @default.
- W2009849608 cites W1989498031 @default.
- W2009849608 doi "https://doi.org/10.1016/0005-2787(75)90248-8" @default.
- W2009849608 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/164244" @default.
- W2009849608 hasPublicationYear "1975" @default.
- W2009849608 type Work @default.
- W2009849608 sameAs 2009849608 @default.
- W2009849608 citedByCount "1" @default.
- W2009849608 crossrefType "journal-article" @default.
- W2009849608 hasAuthorship W2009849608A5004982119 @default.
- W2009849608 hasAuthorship W2009849608A5053024250 @default.
- W2009849608 hasConcept C134018914 @default.
- W2009849608 hasConcept C168240541 @default.
- W2009849608 hasConcept C181199279 @default.
- W2009849608 hasConcept C185592680 @default.
- W2009849608 hasConcept C24998067 @default.
- W2009849608 hasConcept C2778473333 @default.
- W2009849608 hasConcept C28859421 @default.
- W2009849608 hasConcept C3675279 @default.
- W2009849608 hasConcept C501593827 @default.
- W2009849608 hasConcept C515207424 @default.
- W2009849608 hasConcept C55493867 @default.
- W2009849608 hasConcept C86803240 @default.
- W2009849608 hasConcept C87644729 @default.
- W2009849608 hasConceptScore W2009849608C134018914 @default.
- W2009849608 hasConceptScore W2009849608C168240541 @default.
- W2009849608 hasConceptScore W2009849608C181199279 @default.
- W2009849608 hasConceptScore W2009849608C185592680 @default.
- W2009849608 hasConceptScore W2009849608C24998067 @default.
- W2009849608 hasConceptScore W2009849608C2778473333 @default.
- W2009849608 hasConceptScore W2009849608C28859421 @default.
- W2009849608 hasConceptScore W2009849608C3675279 @default.
- W2009849608 hasConceptScore W2009849608C501593827 @default.
- W2009849608 hasConceptScore W2009849608C515207424 @default.
- W2009849608 hasConceptScore W2009849608C55493867 @default.
- W2009849608 hasConceptScore W2009849608C86803240 @default.
- W2009849608 hasConceptScore W2009849608C87644729 @default.
- W2009849608 hasIssue "1" @default.
- W2009849608 hasLocation W20098496081 @default.
- W2009849608 hasLocation W20098496082 @default.
- W2009849608 hasOpenAccess W2009849608 @default.
- W2009849608 hasPrimaryLocation W20098496081 @default.
- W2009849608 hasRelatedWork W122755718 @default.
- W2009849608 hasRelatedWork W1534278265 @default.
- W2009849608 hasRelatedWork W1977392142 @default.
- W2009849608 hasRelatedWork W2004312381 @default.
- W2009849608 hasRelatedWork W2025947841 @default.
- W2009849608 hasRelatedWork W2032553387 @default.
- W2009849608 hasRelatedWork W2093059770 @default.
- W2009849608 hasRelatedWork W2409612133 @default.
- W2009849608 hasRelatedWork W2413734741 @default.
- W2009849608 hasRelatedWork W2440481357 @default.
- W2009849608 hasVolume "383" @default.
- W2009849608 isParatext "false" @default.
- W2009849608 isRetracted "false" @default.
- W2009849608 magId "2009849608" @default.
- W2009849608 workType "article" @default.