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• W2009876096 abstract "ERG's were recorded from dark adapted albino rats using corneal electrodes in response to stimuli varying in intensity and duration, and during the recovery from a mild light adaptation. The amplitudes, latencies, and peak latencies of the a-wave, the multiple peaks in the b-wave, and the negative wave following the b-wave were obtained as a function of these stimuli. The b-wave amplitude increases with stimulus duration when a constant low intensity stimulus is used, but decreases with stimulus duration for high intensity stimuli. The b-wave peak latency remained constant while the b-wave amplitude increased with increasing stimulus intensity, but decreased in the region in which the b-wave amplitude remained constant. Shortly after an adapting light is turned off, a small peak appears on the descending edge of the b-wave. This peak increases in amplitude with increasing dark adaptation until it becomes the most dominant peak in the b-wave. At that time there is a discontinuity in the overall b-wave peak latency vs. recovery time curve to a higher value. The amplitudes and peak latencies of the individual peaks in the b-wave are continuous, however. The results are interpreted in terms of a model that assumes that the b-wave is composed of a number of sub-waves. Each sub-wave can be the result of a different homogeneous population of retinal cells interacting with the light stimulus, or by a series of reactions occurring within the retina, leading to the generation of an electrical potential. Each population of cells would have different thresholds, latencies and sensitivities. The summation of the reactions of all the different populations of cells to the same stimulus results in the b-wave. It is proposed that the lowest threshold (most sensitive) populations of cells produce sub-waves having the longest latencies and that these sub-waves are the first to be affected by light adaptation." @default.
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• W2009876096 date "1967-11-01" @default.
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• W2009876096 title "Sub-wave nature of the albino rat electroretinogram" @default.
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• W2009876096 doi "https://doi.org/10.1016/0303-2647(67)90005-6" @default.
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