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- W2009898623 abstract "The concentrations of doxycycline and 4-de-dimethylaminotetracycline required to inhibit 50% of collagenase activity were found to be 15 to 30 microM for human neutrophil and gingival crevicular fluid collagenases. Fibroblast collagenase was relatively resistant to inhibition by tetracyclines; the 50% inhibitory concentrations of doxycycline and 4-de-dimethylaminotetracycline were 280 and 510 microM, respectively." @default.
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- W2009898623 date "1992-01-01" @default.
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- W2009898623 title "Specificity of the anticollagenase action of tetracyclines: relevance to their anti-inflammatory potential" @default.
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- W2009898623 doi "https://doi.org/10.1128/aac.36.1.227" @default.
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