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- W2009968653 abstract "To the Editor:— When one makes a wheal in the skin with 0.1 cc. of an ordinary suspension of hydrocortisone, semi-permanent changes remain at the site. A yellowish-white, barely raised punctum gathers at the center of a delicately pseudoatrophic, circinate, half-penny-sized patch. The injection itself is painless, as is simultaneous injection of almost any other drug, and no spontaneous subjective sensation follows. It takes about a week or two for the central punctum to form. In the meantime a barely apparent puffiness is present. Histological study shows crystals distributed within the cutis but crowded within what is seen grossly as the central yellowish point. After 10 to 14 months this central hillock crumbles, its content extrudes itself, and what looked like an atrophic area turns out to be normal skin. The entire area of pseudoatrophy is hypalgesic and remains so until the accumulated crystals work their way out of the" @default.
- W2009968653 created "2016-06-24" @default.
- W2009968653 creator A5073479245 @default.
- W2009968653 date "1954-11-27" @default.
- W2009968653 modified "2023-09-26" @default.
- W2009968653 title "HYDROCORTISONE ISLANDS FOR HYPALGESIC INJECTIONS" @default.
- W2009968653 doi "https://doi.org/10.1001/jama.1954.02950130056023" @default.
- W2009968653 hasPublicationYear "1954" @default.
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