FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009969137> ?p ?o ?g. }

• W2009969137 endingPage "549" @default.
• W2009969137 startingPage "542" @default.
• W2009969137 abstract "The mechanism by which dobutamine increases the contraction of chronically dysfunctional myocardium and its effects on metabolism are still unknown. The aim of this study was to assess regional myocardial metabolism at rest and during an intracoronary dobutamine infusion in patients with hibernating myocardium. Eleven asymptomatic patients with single proximal stenosis of the left anterior descending coronary artery and persistent left ventricular dysfunction at rest (undergoing percutaneous transluminal coronary angioplasty [PTCA]) were studied prospectively. Regional left ventricular function was assessed by two-dimensional (2D) echocardiography and regional perfusion by thallium-201 single-proton-emission computed tomography. Great cardiac vein and aortic blood samples were obtained for measurements of lactate and plasma free fatty acid (FFA) concentrations. Inotropic challenge, obtained by using intracoronary dobutamine infusion, increases regional left ventricular function. However, the arteriovenous AV lactate difference was 0.206 = 0.070 mmol/L at rest, and it decreased to 0.018 = 0.069 mmol/L (p < 0.05 vs baseline) and 0.066 = 0.068 mmol/L (p < 0.05 vs baseline) at 4 and 10 minutes of dobutamine infusion, respectively. Thus the hibernating myocardium does not produce lactate at rest. However, when regional contraction is stimulated, dobutamine-induced inotropic challenge may cause a perfusion-contraction mismatch with an activation of anaerobic glycolysis." @default.
• W2009969137 created "2016-06-24" @default.
• W2009969137 creator A5003180371 @default.
• W2009969137 creator A5016385364 @default.
• W2009969137 creator A5028815239 @default.
• W2009969137 creator A5041185771 @default.
• W2009969137 creator A5051324603 @default.
• W2009969137 creator A5063924184 @default.
• W2009969137 creator A5068281952 @default.
• W2009969137 creator A5073037854 @default.
• W2009969137 creator A5074115401 @default.
• W2009969137 date "1996-09-01" @default.
• W2009969137 modified "2023-10-16" @default.
• W2009969137 title "Inotropic stimulation by dobutamine increases left ventricular regional function at the expense of metabolism in hibernating myocardium" @default.
• W2009969137 cites W1976508798 @default.
• W2009969137 cites W1979182111 @default.
• W2009969137 cites W1979584223 @default.
• W2009969137 cites W1981576632 @default.
• W2009969137 cites W1987579201 @default.
• W2009969137 cites W1987960154 @default.
• W2009969137 cites W1992062589 @default.
• W2009969137 cites W1997277843 @default.
• W2009969137 cites W2003200336 @default.
• W2009969137 cites W2003903433 @default.
• W2009969137 cites W2007521606 @default.
• W2009969137 cites W2015390581 @default.
• W2009969137 cites W2044561741 @default.
• W2009969137 cites W2047399325 @default.
• W2009969137 cites W2048175853 @default.
• W2009969137 cites W2048842335 @default.
• W2009969137 cites W2064677835 @default.
• W2009969137 cites W2067991743 @default.
• W2009969137 cites W2073054029 @default.
• W2009969137 cites W2076720889 @default.
• W2009969137 cites W2087531534 @default.
• W2009969137 cites W2089651556 @default.
• W2009969137 cites W2109052957 @default.
• W2009969137 cites W2110989343 @default.
• W2009969137 cites W2113936179 @default.
• W2009969137 cites W2130314308 @default.
• W2009969137 cites W2147890982 @default.
• W2009969137 cites W2156682207 @default.
• W2009969137 cites W2163966026 @default.
• W2009969137 cites W2990123797 @default.
• W2009969137 doi "https://doi.org/10.1016/s0002-8703(96)90236-7" @default.
• W2009969137 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8800023" @default.
• W2009969137 hasPublicationYear "1996" @default.
• W2009969137 type Work @default.
• W2009969137 sameAs 2009969137 @default.
• W2009969137 citedByCount "42" @default.
• W2009969137 countsByYear W20099691372013 @default.
• W2009969137 countsByYear W20099691372014 @default.
• W2009969137 countsByYear W20099691372017 @default.
• W2009969137 countsByYear W20099691372018 @default.
• W2009969137 countsByYear W20099691372019 @default.
• W2009969137 countsByYear W20099691372021 @default.
• W2009969137 crossrefType "journal-article" @default.
• W2009969137 hasAuthorship W2009969137A5003180371 @default.
• W2009969137 hasAuthorship W2009969137A5016385364 @default.
• W2009969137 hasAuthorship W2009969137A5028815239 @default.
• W2009969137 hasAuthorship W2009969137A5041185771 @default.
• W2009969137 hasAuthorship W2009969137A5051324603 @default.
• W2009969137 hasAuthorship W2009969137A5063924184 @default.
• W2009969137 hasAuthorship W2009969137A5068281952 @default.
• W2009969137 hasAuthorship W2009969137A5073037854 @default.
• W2009969137 hasAuthorship W2009969137A5074115401 @default.
• W2009969137 hasConcept C126322002 @default.
• W2009969137 hasConcept C146957229 @default.
• W2009969137 hasConcept C155710745 @default.
• W2009969137 hasConcept C163415756 @default.
• W2009969137 hasConcept C164705383 @default.
• W2009969137 hasConcept C178853913 @default.
• W2009969137 hasConcept C2779464278 @default.
• W2009969137 hasConcept C2780062172 @default.
• W2009969137 hasConcept C2781185063 @default.
• W2009969137 hasConcept C500558357 @default.
• W2009969137 hasConcept C71924100 @default.
• W2009969137 hasConceptScore W2009969137C126322002 @default.
• W2009969137 hasConceptScore W2009969137C146957229 @default.
• W2009969137 hasConceptScore W2009969137C155710745 @default.
• W2009969137 hasConceptScore W2009969137C163415756 @default.
• W2009969137 hasConceptScore W2009969137C164705383 @default.
• W2009969137 hasConceptScore W2009969137C178853913 @default.
• W2009969137 hasConceptScore W2009969137C2779464278 @default.
• W2009969137 hasConceptScore W2009969137C2780062172 @default.
• W2009969137 hasConceptScore W2009969137C2781185063 @default.
• W2009969137 hasConceptScore W2009969137C500558357 @default.
• W2009969137 hasConceptScore W2009969137C71924100 @default.
• W2009969137 hasIssue "3" @default.
• W2009969137 hasLocation W20099691371 @default.
• W2009969137 hasLocation W20099691372 @default.
• W2009969137 hasOpenAccess W2009969137 @default.
• W2009969137 hasPrimaryLocation W20099691371 @default.
• W2009969137 hasRelatedWork W1974262633 @default.
• W2009969137 hasRelatedWork W1976224385 @default.
• W2009969137 hasRelatedWork W2005061266 @default.
• W2009969137 hasRelatedWork W2008993463 @default.
• W2009969137 hasRelatedWork W2039862190 @default.

• next