FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2009969151> ?p ?o ?g. }

• W2009969151 endingPage "1168" @default.
• W2009969151 startingPage "1162" @default.
• W2009969151 abstract "In Brief OBJECTIVE: To compare the efficacy of the vaginal and sublingual administration of the synthetic prostaglandin misoprostol with the currently used oral administration route in second-trimester medical abortion. METHODS: This was a prospective randomized trial of medical abortion with misoprostol after mifepristone priming at 14–24 weeks of gestation. From 2009 to 2013, recruited women received 200 mg mifepristone orally followed 24–48 hours later by an 800-microgram vaginal loading dose of misoprostol. Women were then randomized to receive additional 400-microgram misoprostol doses orally every 3 hours, vaginally every 4 hours, or sublingually every 3 hours. The main outcome was the duration of abortion with emphasis on the proportion of women undelivered 12 hours after the misoprostol loading dose in the three groups. RESULTS: A total of 302 women were randomized: 100 to oral, 100 to vaginal, and 102 to sublingual misoprostol. The median gestation at recruitment was oral 19.1 weeks (interquartile range 17.2–20.8), vaginal 19.4 weeks (interquartile range 17.3–20.4), and sublingual 19.7 weeks (interquartile range 17.6–21.0). The overall abortion duration was longer in women receiving oral misoprostol: oral 9.5 hours (95% confidence interval [CI] 8.5–11.4), vaginal 7.4 hours (95% CI 6.5–8.2), and sublingual 7.8 hours (95% CI 7.0–9.2). Overall, 84 of 302 (27.8%) women were undelivered at 12 hours, comprising 37.0% (95% CI 28.7–47.8) oral, 20.5% (95% CI 14.0–30.1) vaginal, and 21.0% (95% CI 14.3–30.7) sublingual groups. CONCLUSION: Vaginal or sublingual misoprostol administered after a vaginal loading dose in second-trimester medical abortion with mifepristone priming is associated with a shorter time to pregnancy termination compared with an oral regimen. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, www.clinicaltrials.gov, NCT00864799. LEVEL OF EVIDENCE: I After mifepristone priming in the second trimester of pregnancy, oral misoprostol results in a longer abortion duration than the vaginal or sublingual route." @default.
• W2009969151 created "2016-06-24" @default.
• W2009969151 creator A5035632452 @default.
• W2009969151 creator A5051904954 @default.
• W2009969151 creator A5081410354 @default.
• W2009969151 date "2014-06-01" @default.
• W2009969151 modified "2023-10-18" @default.
• W2009969151 title "Mifepristone and Oral, Vaginal, or Sublingual Misoprostol for Second-Trimester Abortion" @default.
• W2009969151 cites W1917913033 @default.
• W2009969151 cites W1967997699 @default.
• W2009969151 cites W1971833442 @default.
• W2009969151 cites W1995565423 @default.
• W2009969151 cites W2041120294 @default.
• W2009969151 cites W2045714701 @default.
• W2009969151 cites W2053822073 @default.
• W2009969151 cites W2071065598 @default.
• W2009969151 cites W2072433951 @default.
• W2009969151 cites W2074913537 @default.
• W2009969151 cites W2077921906 @default.
• W2009969151 cites W2123449208 @default.
• W2009969151 cites W2124342314 @default.
• W2009969151 cites W2126997469 @default.
• W2009969151 cites W2161872135 @default.
• W2009969151 cites W2167156251 @default.
• W2009969151 doi "https://doi.org/10.1097/aog.0000000000000290" @default.
• W2009969151 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24807339" @default.
• W2009969151 hasPublicationYear "2014" @default.
• W2009969151 type Work @default.
• W2009969151 sameAs 2009969151 @default.
• W2009969151 citedByCount "33" @default.
• W2009969151 countsByYear W20099691512014 @default.
• W2009969151 countsByYear W20099691512015 @default.
• W2009969151 countsByYear W20099691512016 @default.
• W2009969151 countsByYear W20099691512017 @default.
• W2009969151 countsByYear W20099691512018 @default.
• W2009969151 countsByYear W20099691512019 @default.
• W2009969151 countsByYear W20099691512020 @default.
• W2009969151 countsByYear W20099691512021 @default.
• W2009969151 countsByYear W20099691512023 @default.
• W2009969151 crossrefType "journal-article" @default.
• W2009969151 hasAuthorship W2009969151A5035632452 @default.
• W2009969151 hasAuthorship W2009969151A5051904954 @default.
• W2009969151 hasAuthorship W2009969151A5081410354 @default.
• W2009969151 hasConcept C119060515 @default.
• W2009969151 hasConcept C131872663 @default.
• W2009969151 hasConcept C141071460 @default.
• W2009969151 hasConcept C168563851 @default.
• W2009969151 hasConcept C2776106523 @default.
• W2009969151 hasConcept C2777744392 @default.
• W2009969151 hasConcept C2778642596 @default.
• W2009969151 hasConcept C2778723060 @default.
• W2009969151 hasConcept C2778826759 @default.
• W2009969151 hasConcept C2779199973 @default.
• W2009969151 hasConcept C2779234561 @default.
• W2009969151 hasConcept C2779350572 @default.
• W2009969151 hasConcept C2779560327 @default.
• W2009969151 hasConcept C29456083 @default.
• W2009969151 hasConcept C42219234 @default.
• W2009969151 hasConcept C46973012 @default.
• W2009969151 hasConcept C54355233 @default.
• W2009969151 hasConcept C71924100 @default.
• W2009969151 hasConcept C86803240 @default.
• W2009969151 hasConceptScore W2009969151C119060515 @default.
• W2009969151 hasConceptScore W2009969151C131872663 @default.
• W2009969151 hasConceptScore W2009969151C141071460 @default.
• W2009969151 hasConceptScore W2009969151C168563851 @default.
• W2009969151 hasConceptScore W2009969151C2776106523 @default.
• W2009969151 hasConceptScore W2009969151C2777744392 @default.
• W2009969151 hasConceptScore W2009969151C2778642596 @default.
• W2009969151 hasConceptScore W2009969151C2778723060 @default.
• W2009969151 hasConceptScore W2009969151C2778826759 @default.
• W2009969151 hasConceptScore W2009969151C2779199973 @default.
• W2009969151 hasConceptScore W2009969151C2779234561 @default.
• W2009969151 hasConceptScore W2009969151C2779350572 @default.
• W2009969151 hasConceptScore W2009969151C2779560327 @default.
• W2009969151 hasConceptScore W2009969151C29456083 @default.
• W2009969151 hasConceptScore W2009969151C42219234 @default.
• W2009969151 hasConceptScore W2009969151C46973012 @default.
• W2009969151 hasConceptScore W2009969151C54355233 @default.
• W2009969151 hasConceptScore W2009969151C71924100 @default.
• W2009969151 hasConceptScore W2009969151C86803240 @default.
• W2009969151 hasIssue "6" @default.
• W2009969151 hasLocation W20099691511 @default.
• W2009969151 hasOpenAccess W2009969151 @default.
• W2009969151 hasPrimaryLocation W20099691511 @default.
• W2009969151 hasRelatedWork W1602576566 @default.
• W2009969151 hasRelatedWork W1985590144 @default.
• W2009969151 hasRelatedWork W2004394272 @default.
• W2009969151 hasRelatedWork W2009969151 @default.
• W2009969151 hasRelatedWork W2016603468 @default.
• W2009969151 hasRelatedWork W2070710373 @default.
• W2009969151 hasRelatedWork W2382213285 @default.
• W2009969151 hasRelatedWork W2386756592 @default.
• W2009969151 hasRelatedWork W2393206650 @default.
• W2009969151 hasRelatedWork W4293216935 @default.
• W2009969151 hasVolume "123" @default.
• W2009969151 isParatext "false" @default.
• W2009969151 isRetracted "false" @default.

• next