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- W2009969440 abstract "A hemophilliac with a factor VIII inhibitor was bleeding massively from an extensive surgical wound. After ten days of unsuccessful management by conservative measures, he was given a single infusion of prothrombin complex concentrate (Konyne). Bleeding stopped immediately and the wound healed without further recurrence of bleeding. Although the activated partial thromboplastin time shortened following the infusion, the exact physiologic mechanism whereby these concentrates bypass the need for factor VIII clotting activity is unknown." @default.
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- W2009969440 date "1977-09-01" @default.
- W2009969440 modified "2023-10-12" @default.
- W2009969440 title "Prothrombin complex concentrate" @default.
- W2009969440 doi "https://doi.org/10.1001/archinte.137.9.1211" @default.
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