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- W2010019323 abstract "Purpose of review To review current knowledge and recent advances in food protein-induced enterocolitis syndrome (FPIES). Recent findings Rice is the most common solid food causing FPIES. Rice FPIES is associated with more severe reactions than other foods. Infants presenting acutely may be hypothermic (<36°C) and have thrombocytosis. Finding of hypoalbuminemia and weight gain less than 10 g/day helps to differentiate chronic infantile cow's milk FPIES from infectious causes. Gastric juice leukocytes more than 10 cells per high-power field are found in infants with positive oral food challenge to cow's milk. Summary FPIES is a non-IgE-mediated gastrointestinal food hypersensitivity disorder. Food protein-activated intestinal lymphocytes elaborate inflammatory cytokines that result in increased intestinal permeability, malabsorption, dysmotility, emesis, diarrhea, pain, and failure to thrive. Decreased intestinal transforming growth factor beta and increased TNFα may be important in FPIES. Cow's milk and soy are the most common causes of FPIES, but cereal grains (rice, oat, and barley), fish, poultry, and vegetables may also cause FPIES. The majority of FPIES resolve by age of 3 years." @default.
- W2010019323 created "2016-06-24" @default.
- W2010019323 creator A5052548559 @default.
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- W2010019323 date "2009-08-01" @default.
- W2010019323 modified "2023-10-07" @default.
- W2010019323 title "Food protein-induced enterocolitis syndrome" @default.
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- W2010019323 doi "https://doi.org/10.1097/aci.0b013e32832d6315" @default.
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