FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010026255> ?p ?o ?g. }

• W2010026255 endingPage "1622" @default.
• W2010026255 startingPage "1613" @default.
• W2010026255 abstract "The incidence of overall (acute and delayed) chemotherapy-induced nausea and vomiting (CINV) events among patients treated with single- and multi-day low emetogenic chemotherapy (LEC) is not well established. We studied a cohort of patients receiving LEC and antiemetic prophylaxis with palonosetron (Group 1) versus other 5-HT(3) receptor antagonists (5-HT(3)-RAs) (Group 2), to determine the overall rate of CINV and the proportion of patients experiencing delayed CINV (days 2-7 of a CT cycle) in a hospital outpatient setting.Patients aged ≥18 years with cancer diagnosis initiating single-day and multi-day LEC for the first time between 4/1/2007 and 3/31/2009 were identified from the Premier Perspective database. CINV events (ICD-9-CM codes for nausea, vomiting, or volume depletion or CINV-related rescue medications) were assessed descriptively. A generalized linear multivariate regression model was developed, estimating the overall CINV event rate among Group 1 and 2 patients in the follow-up period (first of eight chemotherapy [CT] cycles or 6 months).In the follow-up period, out of a total of 10,137 overall CINV events (single-day and multi-day LEC), 8783 events (86.6%) were identified in single-day LEC treated patients. Within single-day LEC treated events, in the first cycle, of 3184 events, 2996 (94.1%) events were delayed. Average number of delayed events per patient remained consistent throughout the eight cycles (3.1 [1st cycle] vs. 2.9 [8th cycle]; P = 0.842]). Among 2439 patients on antiemetic prophylaxis with a 5-HT(3)-RA, 10.1% (n = 247) initiated palonosetron. Regression analysis indicated that Group 1 patients (versus Group 2) had a 15.2% reduction in CINV event rate per CT cycle; P = 0.0403. Study limitations include potential lack of generalizability, absence of data on certain confounders including alcohol consumption and prior history of motion sickness, potential underestimation of incidence of uncontrolled CINV, and inability to draw conclusions pertaining to cause and effect relationship.In this retrospective analysis, delayed CINV comprised a major proportion of overall CINV among cancer diagnosed patients on single-day LEC. Additionally, palonosetron prophylaxis was associated with a significantly lower overall CINV event rate versus other 5-HT(3)-RA prophylaxis in single- and multi-day LEC treatment." @default.
• W2010026255 created "2016-06-24" @default.
• W2010026255 creator A5015721711 @default.
• W2010026255 creator A5019554240 @default.
• W2010026255 creator A5041884618 @default.
• W2010026255 creator A5060884947 @default.
• W2010026255 creator A5072563567 @default.
• W2010026255 creator A5090864802 @default.
• W2010026255 date "2011-06-22" @default.
• W2010026255 modified "2023-09-27" @default.
• W2010026255 title "Chemotherapy-induced nausea and vomiting and antiemetic prophylaxis with palonosetron versus other 5-HT3 receptor antagonists in patients with cancer treated with low emetogenic chemotherapy in a hospital outpatient setting in the United States" @default.
• W2010026255 cites W1526668328 @default.
• W2010026255 cites W1855182594 @default.
• W2010026255 cites W1973339347 @default.
• W2010026255 cites W2000445173 @default.
• W2010026255 cites W2046417971 @default.
• W2010026255 cites W2047765875 @default.
• W2010026255 cites W2058429916 @default.
• W2010026255 cites W2085646558 @default.
• W2010026255 cites W2089750290 @default.
• W2010026255 cites W2094630375 @default.
• W2010026255 cites W2118261787 @default.
• W2010026255 cites W2120978512 @default.
• W2010026255 cites W2126429670 @default.
• W2010026255 cites W2154792815 @default.
• W2010026255 cites W2155726820 @default.
• W2010026255 cites W2158036326 @default.
• W2010026255 cites W226191656 @default.
• W2010026255 cites W3189546654 @default.
• W2010026255 doi "https://doi.org/10.1185/03007995.2011.596201" @default.
• W2010026255 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21696263" @default.
• W2010026255 hasPublicationYear "2011" @default.
• W2010026255 type Work @default.
• W2010026255 sameAs 2010026255 @default.
• W2010026255 citedByCount "7" @default.
• W2010026255 countsByYear W20100262552012 @default.
• W2010026255 countsByYear W20100262552013 @default.
• W2010026255 countsByYear W20100262552016 @default.
• W2010026255 countsByYear W20100262552017 @default.
• W2010026255 crossrefType "journal-article" @default.
• W2010026255 hasAuthorship W2010026255A5015721711 @default.
• W2010026255 hasAuthorship W2010026255A5019554240 @default.
• W2010026255 hasAuthorship W2010026255A5041884618 @default.
• W2010026255 hasAuthorship W2010026255A5060884947 @default.
• W2010026255 hasAuthorship W2010026255A5072563567 @default.
• W2010026255 hasAuthorship W2010026255A5090864802 @default.
• W2010026255 hasConcept C126322002 @default.
• W2010026255 hasConcept C143998085 @default.
• W2010026255 hasConcept C2776712918 @default.
• W2010026255 hasConcept C2779924295 @default.
• W2010026255 hasConcept C2780580376 @default.
• W2010026255 hasConcept C2780852908 @default.
• W2010026255 hasConcept C2780884295 @default.
• W2010026255 hasConcept C42219234 @default.
• W2010026255 hasConcept C71924100 @default.
• W2010026255 hasConceptScore W2010026255C126322002 @default.
• W2010026255 hasConceptScore W2010026255C143998085 @default.
• W2010026255 hasConceptScore W2010026255C2776712918 @default.
• W2010026255 hasConceptScore W2010026255C2779924295 @default.
• W2010026255 hasConceptScore W2010026255C2780580376 @default.
• W2010026255 hasConceptScore W2010026255C2780852908 @default.
• W2010026255 hasConceptScore W2010026255C2780884295 @default.
• W2010026255 hasConceptScore W2010026255C42219234 @default.
• W2010026255 hasConceptScore W2010026255C71924100 @default.
• W2010026255 hasIssue "8" @default.
• W2010026255 hasLocation W20100262551 @default.
• W2010026255 hasLocation W20100262552 @default.
• W2010026255 hasOpenAccess W2010026255 @default.
• W2010026255 hasPrimaryLocation W20100262551 @default.
• W2010026255 hasRelatedWork W2121534313 @default.
• W2010026255 hasRelatedWork W2130685433 @default.
• W2010026255 hasRelatedWork W2139336814 @default.
• W2010026255 hasRelatedWork W2168688660 @default.
• W2010026255 hasRelatedWork W2305256837 @default.
• W2010026255 hasRelatedWork W2549713971 @default.
• W2010026255 hasRelatedWork W2589214579 @default.
• W2010026255 hasRelatedWork W2590095022 @default.
• W2010026255 hasRelatedWork W2590915793 @default.
• W2010026255 hasRelatedWork W2603788632 @default.
• W2010026255 hasRelatedWork W2621644069 @default.
• W2010026255 hasRelatedWork W2748432207 @default.
• W2010026255 hasRelatedWork W2765530808 @default.
• W2010026255 hasRelatedWork W2784828921 @default.
• W2010026255 hasRelatedWork W2895223856 @default.
• W2010026255 hasRelatedWork W3132262304 @default.
• W2010026255 hasRelatedWork W3166470762 @default.
• W2010026255 hasRelatedWork W3166757738 @default.
• W2010026255 hasRelatedWork W3169388996 @default.
• W2010026255 hasRelatedWork W2740070693 @default.
• W2010026255 hasVolume "27" @default.
• W2010026255 isParatext "false" @default.
• W2010026255 isRetracted "false" @default.
• W2010026255 magId "2010026255" @default.
• W2010026255 workType "article" @default.