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- W2010039265 abstract "METRONIDAZOLE is usually prescribed for therapeutic courses of one to ten days, but in rare instances it may be administered for longer periods. Two such circumstances involve treatment of recurrent antibioticinduced colitis and treatment of inflammation in a Kock pouch (an internal reservoir and nipple valve created from distal ileum in patients undergoing total colectomy).<sup>1</sup>This inflammation of the pouch is characterized clinically by profuse, watery diarrhea and occasionally by bleeding and incontinence. The symptoms respond to antibiotics, making a bacterial cause seem most likely. Metronidazole is the most effective drug for this condition, but sometimes other antibiotics are effective.<sup>1</sup> <h3>Report of a Case</h3> A 36-year-old man with ulcerative colitis underwent total colectomy and creation of a Kock pouch in May 1983. Recurrent episodes of pouch inflammation, characterized by profuse watery diarrhea and mild right lower-quadrant aching, responded transiently to short courses (five to ten days) of either" @default.
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- W2010039265 date "1985-12-13" @default.
- W2010039265 modified "2023-09-27" @default.
- W2010039265 title "Metronidazole-lnduced Gynecomastia" @default.
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- W2010039265 doi "https://doi.org/10.1001/jama.1985.03360220083034" @default.
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