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- W2010053659 abstract "To determine whether sensitivity to polyethylene particles varies among patients, we studied 25 patients who had undergone total hip arthroplasty. We used pelvic radiographs to measure annual polyethylene wear and the area of osteolysis. The ratio of the area of osteolysis to the volumetric polyethylene wear was defined as sensitivity index. Adherent cells from peripheral blood were cocultured with polyethylene particles, and the amount of bone-resorptive cytokines was measured. The amount of interleukin-6, but not of interleukin -1β or tumor necrosis factor-α, released from adherent cells in the in vitro experiment correlated with the in vivo sensitivity indices. This technique appears capable of predicting the development of polyethylene-induced osteolysis, allowing surgeons to avoid using polyethylene as the bearing surface in patients at risk for osteolysis." @default.
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- W2010053659 date "2007-10-01" @default.
- W2010053659 modified "2023-10-16" @default.
- W2010053659 title "Patient Sensitivity to Polyethylene Particles with Cemented Total Hip Arthroplasty" @default.
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- W2010053659 doi "https://doi.org/10.1016/j.arth.2007.04.033" @default.
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