Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010094375> ?p ?o ?g. }
- W2010094375 endingPage "43" @default.
- W2010094375 startingPage "37" @default.
- W2010094375 abstract "Phosphatidylinositol 3-phosphate [PtdIns(3)P] acts as a second messenger via the recruitment of diverse signalling proteins to various cellular compartments. Recent advances have highlighted the association of human diseases with mutations in phosphatases that regulate PtdIns(3)P levels. Myotubularin, the gene mutated in myotubular myopathy, functions as a lipid phosphatase with specificity for PtdIns(3)P. It is now apparent that there is an increasing family of proteins that are defined by their significant homology with myotubularin. The myotubularin-related gene family includes proteins that exhibit a lipid phosphatase catalytic motif, those that contain mutations of the critical catalytic residues, and at least one protein that functions as an adapter subunit for PtdIns(3)P-3-phosphatase activity. The present challenge is to understand how deregulation of phosphoinositide metabolism causes human disease." @default.
- W2010094375 created "2016-06-24" @default.
- W2010094375 creator A5016659008 @default.
- W2010094375 creator A5036596442 @default.
- W2010094375 date "2002-01-01" @default.
- W2010094375 modified "2023-10-17" @default.
- W2010094375 title "The Myotubularin Family: Novel Phosphoinositide Regulators" @default.
- W2010094375 cites W1496054948 @default.
- W2010094375 cites W1499176799 @default.
- W2010094375 cites W1517631297 @default.
- W2010094375 cites W1574748879 @default.
- W2010094375 cites W1581364974 @default.
- W2010094375 cites W1614056212 @default.
- W2010094375 cites W1632617569 @default.
- W2010094375 cites W1939083266 @default.
- W2010094375 cites W1971893931 @default.
- W2010094375 cites W1973577899 @default.
- W2010094375 cites W1973593487 @default.
- W2010094375 cites W1975573101 @default.
- W2010094375 cites W1977701732 @default.
- W2010094375 cites W1982522630 @default.
- W2010094375 cites W1982813242 @default.
- W2010094375 cites W1984193862 @default.
- W2010094375 cites W1984366092 @default.
- W2010094375 cites W1985764146 @default.
- W2010094375 cites W1993860552 @default.
- W2010094375 cites W1995841153 @default.
- W2010094375 cites W1997306286 @default.
- W2010094375 cites W2001814499 @default.
- W2010094375 cites W2002127663 @default.
- W2010094375 cites W2003787585 @default.
- W2010094375 cites W2003797932 @default.
- W2010094375 cites W2004793364 @default.
- W2010094375 cites W2010502904 @default.
- W2010094375 cites W2013131355 @default.
- W2010094375 cites W2016441216 @default.
- W2010094375 cites W2021303199 @default.
- W2010094375 cites W2029798038 @default.
- W2010094375 cites W2036673687 @default.
- W2010094375 cites W2037370520 @default.
- W2010094375 cites W2040513834 @default.
- W2010094375 cites W2044005459 @default.
- W2010094375 cites W2049651968 @default.
- W2010094375 cites W2067000579 @default.
- W2010094375 cites W2068427129 @default.
- W2010094375 cites W2068831015 @default.
- W2010094375 cites W2080435414 @default.
- W2010094375 cites W2085167130 @default.
- W2010094375 cites W2088882706 @default.
- W2010094375 cites W2094807146 @default.
- W2010094375 cites W2098851635 @default.
- W2010094375 cites W2100739884 @default.
- W2010094375 cites W2103362139 @default.
- W2010094375 cites W2103421087 @default.
- W2010094375 cites W2124360065 @default.
- W2010094375 cites W2128644712 @default.
- W2010094375 cites W2130690259 @default.
- W2010094375 cites W2137399490 @default.
- W2010094375 cites W2141206157 @default.
- W2010094375 cites W2151608325 @default.
- W2010094375 cites W2152988906 @default.
- W2010094375 cites W2156846932 @default.
- W2010094375 cites W2164139183 @default.
- W2010094375 cites W2164638406 @default.
- W2010094375 cites W2167016115 @default.
- W2010094375 cites W2170437356 @default.
- W2010094375 cites W339363 @default.
- W2010094375 doi "https://doi.org/10.1080/15216540210812" @default.
- W2010094375 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12018406" @default.
- W2010094375 hasPublicationYear "2002" @default.
- W2010094375 type Work @default.
- W2010094375 sameAs 2010094375 @default.
- W2010094375 citedByCount "23" @default.
- W2010094375 countsByYear W20100943752013 @default.
- W2010094375 countsByYear W20100943752015 @default.
- W2010094375 countsByYear W20100943752016 @default.
- W2010094375 countsByYear W20100943752017 @default.
- W2010094375 countsByYear W20100943752021 @default.
- W2010094375 crossrefType "journal-article" @default.
- W2010094375 hasAuthorship W2010094375A5016659008 @default.
- W2010094375 hasAuthorship W2010094375A5036596442 @default.
- W2010094375 hasBestOaLocation W20100943751 @default.
- W2010094375 hasConcept C104317684 @default.
- W2010094375 hasConcept C11960822 @default.
- W2010094375 hasConcept C150194340 @default.
- W2010094375 hasConcept C178666793 @default.
- W2010094375 hasConcept C2780610907 @default.
- W2010094375 hasConcept C54355233 @default.
- W2010094375 hasConcept C55493867 @default.
- W2010094375 hasConcept C5911399 @default.
- W2010094375 hasConcept C62478195 @default.
- W2010094375 hasConcept C86803240 @default.
- W2010094375 hasConcept C95444343 @default.
- W2010094375 hasConceptScore W2010094375C104317684 @default.
- W2010094375 hasConceptScore W2010094375C11960822 @default.
- W2010094375 hasConceptScore W2010094375C150194340 @default.
- W2010094375 hasConceptScore W2010094375C178666793 @default.
- W2010094375 hasConceptScore W2010094375C2780610907 @default.