FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010115213> ?p ?o ?g. }

• W2010115213 endingPage "725" @default.
• W2010115213 startingPage "711" @default.
• W2010115213 abstract "Asthma is a chronic inflammatory disorder of the airways in which many cells and cellular elements play a role. Chronic inflammation is associated with airway hyper-responsiveness that leads to recurrent episodes of wheezing, breathlessness, chest tightness and coughing, as well as variable airflow obstruction within the lung. With time, such airflow obstruction may become permanent due to remodeling. It has been treated for more than 100 years by subcutaneous immunotherapy with allergen extracts but in recent years, other forms and types of immunotherapy have been introduced. Perhaps the most successful of these to date, is sublingual immunotherapy, which has attained significant usage in European countries but has yet to make inroads into clinical practice in North America. Other mechanisms to modify the inflammatory responses of asthma have included immunotherapy with recombinant allergens, the use of allergen peptides targeting antigen-specific T cells and the administration of Toll-like receptor agonists coupled to allergen proteins. As the inflammatory responses in asthma frequently involve IgE, a modified monoclonal antibody to IgE and interfering with its binding to the IgE receptor have gained acceptance for treating severe allergic asthma. Other monoclonal antibodies or recombinant receptor antagonists are being assessed for their ability to block other contributors to the inflammatory response. Finally, attempts have been made to generate autoantibody responses to cytokines implicated in asthma. Most of these therapies aim to modify or inhibit the so-called Th 2 immune response, which is implicated in many forms of asthma, or to inhibit cytokines involved in these responses. However, an added benefit of classical immunotherapy seems to be the ability to prevent the allergic progression to new sensitivities and new forms of allergic disease." @default.
• W2010115213 created "2016-06-24" @default.
• W2010115213 creator A5034593049 @default.
• W2010115213 date "2010-09-01" @default.
• W2010115213 modified "2023-09-24" @default.
• W2010115213 title "Immunotherapy in asthma" @default.
• W2010115213 cites W1497484541 @default.
• W2010115213 cites W1531011404 @default.
• W2010115213 cites W1543287522 @default.
• W2010115213 cites W1559228527 @default.
• W2010115213 cites W1565152443 @default.
• W2010115213 cites W1805155421 @default.
• W2010115213 cites W1846706131 @default.
• W2010115213 cites W1859203717 @default.
• W2010115213 cites W1918522022 @default.
• W2010115213 cites W1941368018 @default.
• W2010115213 cites W1947099084 @default.
• W2010115213 cites W1964022370 @default.
• W2010115213 cites W1964196894 @default.
• W2010115213 cites W1966105144 @default.
• W2010115213 cites W1966645815 @default.
• W2010115213 cites W1968428761 @default.
• W2010115213 cites W1970648068 @default.
• W2010115213 cites W1972061354 @default.
• W2010115213 cites W1972924632 @default.
• W2010115213 cites W1973188898 @default.
• W2010115213 cites W1974574903 @default.
• W2010115213 cites W1975409228 @default.
• W2010115213 cites W1975797729 @default.
• W2010115213 cites W1976640573 @default.
• W2010115213 cites W1976644560 @default.
• W2010115213 cites W1977149533 @default.
• W2010115213 cites W1977547115 @default.
• W2010115213 cites W1977919951 @default.
• W2010115213 cites W1979650866 @default.
• W2010115213 cites W1984973837 @default.
• W2010115213 cites W1987551591 @default.
• W2010115213 cites W1990977464 @default.
• W2010115213 cites W1991706889 @default.
• W2010115213 cites W1994143412 @default.
• W2010115213 cites W1994585625 @default.
• W2010115213 cites W1996426153 @default.
• W2010115213 cites W1996904229 @default.
• W2010115213 cites W1997543798 @default.
• W2010115213 cites W1998444876 @default.
• W2010115213 cites W1998823882 @default.
• W2010115213 cites W1999587028 @default.
• W2010115213 cites W2002978114 @default.
• W2010115213 cites W2004107966 @default.
• W2010115213 cites W2005179500 @default.
• W2010115213 cites W2006332559 @default.
• W2010115213 cites W2006454501 @default.
• W2010115213 cites W2007517602 @default.
• W2010115213 cites W2007523022 @default.
• W2010115213 cites W2009608314 @default.
• W2010115213 cites W2010077775 @default.
• W2010115213 cites W2010167279 @default.
• W2010115213 cites W2010998136 @default.
• W2010115213 cites W2011998584 @default.
• W2010115213 cites W2014972792 @default.
• W2010115213 cites W2016175222 @default.
• W2010115213 cites W2016264695 @default.
• W2010115213 cites W2018686087 @default.
• W2010115213 cites W2025111901 @default.
• W2010115213 cites W2025345914 @default.
• W2010115213 cites W2025968022 @default.
• W2010115213 cites W2027291591 @default.
• W2010115213 cites W2028474021 @default.
• W2010115213 cites W2031202979 @default.
• W2010115213 cites W2031717064 @default.
• W2010115213 cites W2032064406 @default.
• W2010115213 cites W2033392452 @default.
• W2010115213 cites W2033441782 @default.
• W2010115213 cites W2036197283 @default.
• W2010115213 cites W2037476918 @default.
• W2010115213 cites W2037509102 @default.
• W2010115213 cites W2039042674 @default.
• W2010115213 cites W2040869635 @default.
• W2010115213 cites W2044792690 @default.
• W2010115213 cites W2047277628 @default.
• W2010115213 cites W2052063445 @default.
• W2010115213 cites W2054187056 @default.
• W2010115213 cites W2054698585 @default.
• W2010115213 cites W2055185143 @default.
• W2010115213 cites W2055432567 @default.
• W2010115213 cites W2057527372 @default.
• W2010115213 cites W2059392211 @default.
• W2010115213 cites W2060933296 @default.
• W2010115213 cites W2062498772 @default.
• W2010115213 cites W2063769680 @default.
• W2010115213 cites W2063907751 @default.
• W2010115213 cites W2064180188 @default.
• W2010115213 cites W2065997245 @default.
• W2010115213 cites W2069362757 @default.
• W2010115213 cites W2073802637 @default.
• W2010115213 cites W2075019839 @default.
• W2010115213 cites W2081375496 @default.
• W2010115213 cites W2085138702 @default.

• next