FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010116997> ?p ?o ?g. }

• W2010116997 endingPage "1777" @default.
• W2010116997 startingPage "1769" @default.
• W2010116997 abstract "Hodgkin lymphoma (HL) shows wide geographic variation in histological subtypes and in its association with the Epstein-Barr virus (EBV). HL has three main epidemiological patterns (I, II and III). Type I pattern, which is prevalent in developing countries, shows a relatively high incidence in male children, a low incidence in the third decade and a second peak of high incidence in older age groups. Type III, which is usually seen in developed countries, is characterised by a low rate in children and a pronounced initial peak in young adults. The third pattern (Type II), which is described in many Asian countries, is intermediate and reflects a transition between types I and III. In this pattern there is both a childhood and a third decade peak. The proportion of EBV positive HL is low in industrialised countries, high in non-industrialised countries and intermediate in early-industrialised countries. Reports from the Arabian Gulf and Middle East are few. The aim of this study is to determine the epidemiology of HL in a population of United Arab Emirates (UAE) nationals, an early industrialised country in the Arabian Gulf, and to delineate the extent of its association with EBV. In total, 88 cases of HL were diagnosed in native patients during the period 1988 through 2004 at Tawam hospital. Forty-five paraffin blocks were available for this study. Five-micrometer sections were prepared and stained with hematoxylin and eosin and the immunohistochemical streptavidin-biotin methods for CD45, CD3, CD20, CD15 and CD30. Other sections were examined for the presence of EBV using the immunohistochemical streptavidin-biotin method for the latent membrane protein 1 and in situ hybridisation for EBV encoded RNA to determine the prevalence of EBV in Hodgkin cells and its possible role in the pathogenesis of HL. Nodular sclerosis (NS) subtype was the most common type of HL among UAE nationals followed by mixed cellularity (MC), lymphocytic predominant (LP), unclassified, lymphocytic depletion (LD) and lymphocyte rich (LR) subtypes, respectively. EBV was seen in 17 of 45 (38%) cases of HL and was predominately seen in the MC subtype followed by NS, LD and LR subtypes, respectively. EBV was more frequently expressed in HL in the pediatric age group than the adult age group. These data indicate that the epidemiology of HL in a native population of the UAE is suggestive of a type II epidemiologic pattern in terms of age distribution, and histopathologic subtypes, whereas the frequency of EBV expression is more suggestive of a type III epidemiologic pattern. The significant association between EBV and HL that we have found further strengthens the suggestion that all cases of HL should be assessed for EBV status, because its presence may have a significant impact on prognosis and response to therapy." @default.
• W2010116997 created "2016-06-24" @default.
• W2010116997 creator A5026162732 @default.
• W2010116997 creator A5077522888 @default.
• W2010116997 creator A5082657273 @default.
• W2010116997 creator A5082759836 @default.
• W2010116997 creator A5090517327 @default.
• W2010116997 date "2008-01-01" @default.
• W2010116997 modified "2023-09-24" @default.
• W2010116997 title "Expression of Epstein–Barr virus in Hodgkin lymphoma in a population of United Arab Emirates nationals" @default.
• W2010116997 cites W1531179 @default.
• W2010116997 cites W1554337334 @default.
• W2010116997 cites W1603845857 @default.
• W2010116997 cites W1842856424 @default.
• W2010116997 cites W1858444101 @default.
• W2010116997 cites W1964120910 @default.
• W2010116997 cites W1966082666 @default.
• W2010116997 cites W1966871658 @default.
• W2010116997 cites W1969582706 @default.
• W2010116997 cites W1974635165 @default.
• W2010116997 cites W1981911143 @default.
• W2010116997 cites W1992415362 @default.
• W2010116997 cites W2018988171 @default.
• W2010116997 cites W2024467435 @default.
• W2010116997 cites W2027293043 @default.
• W2010116997 cites W2032999968 @default.
• W2010116997 cites W2039648819 @default.
• W2010116997 cites W2041993478 @default.
• W2010116997 cites W2049994008 @default.
• W2010116997 cites W2052621715 @default.
• W2010116997 cites W2060007608 @default.
• W2010116997 cites W2063749802 @default.
• W2010116997 cites W2064911152 @default.
• W2010116997 cites W2070141682 @default.
• W2010116997 cites W2087817117 @default.
• W2010116997 cites W2095993904 @default.
• W2010116997 cites W2114344235 @default.
• W2010116997 cites W2124225122 @default.
• W2010116997 cites W2148333546 @default.
• W2010116997 cites W2164925653 @default.
• W2010116997 cites W2286594115 @default.
• W2010116997 cites W4245947014 @default.
• W2010116997 cites W4254845358 @default.
• W2010116997 cites W2182884819 @default.
• W2010116997 cites W2809226744 @default.
• W2010116997 doi "https://doi.org/10.1080/10428190802270894" @default.
• W2010116997 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18661399" @default.
• W2010116997 hasPublicationYear "2008" @default.
• W2010116997 type Work @default.
• W2010116997 sameAs 2010116997 @default.
• W2010116997 citedByCount "30" @default.
• W2010116997 countsByYear W20101169972012 @default.
• W2010116997 countsByYear W20101169972013 @default.
• W2010116997 countsByYear W20101169972014 @default.
• W2010116997 countsByYear W20101169972015 @default.
• W2010116997 countsByYear W20101169972016 @default.
• W2010116997 countsByYear W20101169972017 @default.
• W2010116997 countsByYear W20101169972018 @default.
• W2010116997 countsByYear W20101169972021 @default.
• W2010116997 countsByYear W20101169972022 @default.
• W2010116997 crossrefType "journal-article" @default.
• W2010116997 hasAuthorship W2010116997A5026162732 @default.
• W2010116997 hasAuthorship W2010116997A5077522888 @default.
• W2010116997 hasAuthorship W2010116997A5082657273 @default.
• W2010116997 hasAuthorship W2010116997A5082759836 @default.
• W2010116997 hasAuthorship W2010116997A5090517327 @default.
• W2010116997 hasConcept C107130276 @default.
• W2010116997 hasConcept C120665830 @default.
• W2010116997 hasConcept C121332964 @default.
• W2010116997 hasConcept C142724271 @default.
• W2010116997 hasConcept C144024400 @default.
• W2010116997 hasConcept C149923435 @default.
• W2010116997 hasConcept C187212893 @default.
• W2010116997 hasConcept C2779338263 @default.
• W2010116997 hasConcept C2780430958 @default.
• W2010116997 hasConcept C2908647359 @default.
• W2010116997 hasConcept C2992779791 @default.
• W2010116997 hasConcept C61511704 @default.
• W2010116997 hasConcept C71924100 @default.
• W2010116997 hasConcept C99454951 @default.
• W2010116997 hasConceptScore W2010116997C107130276 @default.
• W2010116997 hasConceptScore W2010116997C120665830 @default.
• W2010116997 hasConceptScore W2010116997C121332964 @default.
• W2010116997 hasConceptScore W2010116997C142724271 @default.
• W2010116997 hasConceptScore W2010116997C144024400 @default.
• W2010116997 hasConceptScore W2010116997C149923435 @default.
• W2010116997 hasConceptScore W2010116997C187212893 @default.
• W2010116997 hasConceptScore W2010116997C2779338263 @default.
• W2010116997 hasConceptScore W2010116997C2780430958 @default.
• W2010116997 hasConceptScore W2010116997C2908647359 @default.
• W2010116997 hasConceptScore W2010116997C2992779791 @default.
• W2010116997 hasConceptScore W2010116997C61511704 @default.
• W2010116997 hasConceptScore W2010116997C71924100 @default.
• W2010116997 hasConceptScore W2010116997C99454951 @default.
• W2010116997 hasIssue "9" @default.
• W2010116997 hasLocation W20101169971 @default.
• W2010116997 hasLocation W20101169972 @default.
• W2010116997 hasOpenAccess W2010116997 @default.

• next