Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010129218> ?p ?o ?g. }
- W2010129218 endingPage "36" @default.
- W2010129218 startingPage "33" @default.
- W2010129218 abstract "We first demonstrated a temporal profile of retinal ganglion cell (RGC) death after axotomy in situ using a newly developed retinal explant culture system. 1,1′- dioctadecyl- 3,3,3′,3′-tetramethylindocarbocyanine perchlorate, a fluorescent tracer, was administered to the superior colliculi of 2 day old Wistar rats to label RGCs retrogradely. Small pieces of retinas were dissected and maintained at the interface between a 5% CO2 atmosphere and culture media, and temporally observed by fluorescent microscopy. The number of surviving RGCs, identified as fluorescent spots, gradually decreased during the course of experiments for up to 10 days in vitro. We identified apoptotic RGCs by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling. Administration of cycloheximide, actinomycin D, or a caspase-3 inhibitor to media significantly decreased RGC death. This system provides a method of quantifying axotomized RGC death in relation to time-dependent changes in an identical retinal slip." @default.
- W2010129218 created "2016-06-24" @default.
- W2010129218 creator A5048153044 @default.
- W2010129218 creator A5054512097 @default.
- W2010129218 creator A5064905331 @default.
- W2010129218 creator A5084164966 @default.
- W2010129218 creator A5084993695 @default.
- W2010129218 creator A5089074853 @default.
- W2010129218 date "2002-12-01" @default.
- W2010129218 modified "2023-09-26" @default.
- W2010129218 title "Quantification of axotomized ganglion cell death by explant culture of the rat retina" @default.
- W2010129218 cites W1624526296 @default.
- W2010129218 cites W1625539280 @default.
- W2010129218 cites W1651988031 @default.
- W2010129218 cites W1760718049 @default.
- W2010129218 cites W1935035216 @default.
- W2010129218 cites W1976411543 @default.
- W2010129218 cites W1977054577 @default.
- W2010129218 cites W1984155636 @default.
- W2010129218 cites W2010247968 @default.
- W2010129218 cites W2017379135 @default.
- W2010129218 cites W2020308246 @default.
- W2010129218 cites W2036481614 @default.
- W2010129218 cites W2051417917 @default.
- W2010129218 cites W2061497413 @default.
- W2010129218 cites W2071487260 @default.
- W2010129218 cites W2079054696 @default.
- W2010129218 cites W2086313670 @default.
- W2010129218 cites W2135406143 @default.
- W2010129218 doi "https://doi.org/10.1016/s0304-3940(02)01047-9" @default.
- W2010129218 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12431769" @default.
- W2010129218 hasPublicationYear "2002" @default.
- W2010129218 type Work @default.
- W2010129218 sameAs 2010129218 @default.
- W2010129218 citedByCount "25" @default.
- W2010129218 countsByYear W20101292182014 @default.
- W2010129218 countsByYear W20101292182015 @default.
- W2010129218 countsByYear W20101292182016 @default.
- W2010129218 countsByYear W20101292182017 @default.
- W2010129218 countsByYear W20101292182018 @default.
- W2010129218 countsByYear W20101292182019 @default.
- W2010129218 countsByYear W20101292182022 @default.
- W2010129218 countsByYear W20101292182023 @default.
- W2010129218 crossrefType "journal-article" @default.
- W2010129218 hasAuthorship W2010129218A5048153044 @default.
- W2010129218 hasAuthorship W2010129218A5054512097 @default.
- W2010129218 hasAuthorship W2010129218A5064905331 @default.
- W2010129218 hasAuthorship W2010129218A5084164966 @default.
- W2010129218 hasAuthorship W2010129218A5084993695 @default.
- W2010129218 hasAuthorship W2010129218A5089074853 @default.
- W2010129218 hasConcept C105702510 @default.
- W2010129218 hasConcept C153911025 @default.
- W2010129218 hasConcept C154113507 @default.
- W2010129218 hasConcept C157890192 @default.
- W2010129218 hasConcept C169760540 @default.
- W2010129218 hasConcept C171056886 @default.
- W2010129218 hasConcept C190283241 @default.
- W2010129218 hasConcept C196795494 @default.
- W2010129218 hasConcept C202751555 @default.
- W2010129218 hasConcept C2777093970 @default.
- W2010129218 hasConcept C2777624874 @default.
- W2010129218 hasConcept C2778128677 @default.
- W2010129218 hasConcept C2779683492 @default.
- W2010129218 hasConcept C31573885 @default.
- W2010129218 hasConcept C3675279 @default.
- W2010129218 hasConcept C55493867 @default.
- W2010129218 hasConcept C86803240 @default.
- W2010129218 hasConcept C95444343 @default.
- W2010129218 hasConceptScore W2010129218C105702510 @default.
- W2010129218 hasConceptScore W2010129218C153911025 @default.
- W2010129218 hasConceptScore W2010129218C154113507 @default.
- W2010129218 hasConceptScore W2010129218C157890192 @default.
- W2010129218 hasConceptScore W2010129218C169760540 @default.
- W2010129218 hasConceptScore W2010129218C171056886 @default.
- W2010129218 hasConceptScore W2010129218C190283241 @default.
- W2010129218 hasConceptScore W2010129218C196795494 @default.
- W2010129218 hasConceptScore W2010129218C202751555 @default.
- W2010129218 hasConceptScore W2010129218C2777093970 @default.
- W2010129218 hasConceptScore W2010129218C2777624874 @default.
- W2010129218 hasConceptScore W2010129218C2778128677 @default.
- W2010129218 hasConceptScore W2010129218C2779683492 @default.
- W2010129218 hasConceptScore W2010129218C31573885 @default.
- W2010129218 hasConceptScore W2010129218C3675279 @default.
- W2010129218 hasConceptScore W2010129218C55493867 @default.
- W2010129218 hasConceptScore W2010129218C86803240 @default.
- W2010129218 hasConceptScore W2010129218C95444343 @default.
- W2010129218 hasIssue "1" @default.
- W2010129218 hasLocation W20101292181 @default.
- W2010129218 hasLocation W20101292182 @default.
- W2010129218 hasOpenAccess W2010129218 @default.
- W2010129218 hasPrimaryLocation W20101292181 @default.
- W2010129218 hasRelatedWork W1500853876 @default.
- W2010129218 hasRelatedWork W1651988031 @default.
- W2010129218 hasRelatedWork W2010171842 @default.
- W2010129218 hasRelatedWork W2035688152 @default.
- W2010129218 hasRelatedWork W2063684229 @default.
- W2010129218 hasRelatedWork W2073754785 @default.
- W2010129218 hasRelatedWork W2121095034 @default.