Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010145174> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2010145174 endingPage "98" @default.
- W2010145174 startingPage "92" @default.
- W2010145174 abstract "Tiflamizole is a fluorinated diarylamidazole sulfone nonsteroidal anti-inflammatory drug not metabolized or excreted in urine. Its mean (+/- SD) elimination t 1/2 from plasma was 21.6 +/- 9 days (range 11.8 to 49.5 days) in 17 subjects with rheumatoid arthritis, and appeared to be first order in most of them. Plasma elimination t 1/2 was loosely related (r = -0.67) to stool frequency in eight subjects for whom stool frequency data were available. In one, cholestyramine decreased t 1/2 to 4.1 days. In two patients, synovial fluid total tiflamizole concentrations were approximately one-third of simultaneous plasma concentrations, but elimination t 1/2s from synovial fluid were of the same order as those from plasma. Even with infrequent dosing, the longer t 1/2 may help sustain the anti-inflammatory effects of this drug." @default.
- W2010145174 created "2016-06-24" @default.
- W2010145174 creator A5006560653 @default.
- W2010145174 creator A5045690666 @default.
- W2010145174 creator A5065911668 @default.
- W2010145174 creator A5073122096 @default.
- W2010145174 date "1984-07-01" @default.
- W2010145174 modified "2023-09-26" @default.
- W2010145174 title "Tiflamizole elimination from plasma in rheumatoid arthritis" @default.
- W2010145174 doi "https://doi.org/10.1038/clpt.1984.145" @default.
- W2010145174 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6734055" @default.
- W2010145174 hasPublicationYear "1984" @default.
- W2010145174 type Work @default.
- W2010145174 sameAs 2010145174 @default.
- W2010145174 citedByCount "3" @default.
- W2010145174 crossrefType "journal-article" @default.
- W2010145174 hasAuthorship W2010145174A5006560653 @default.
- W2010145174 hasAuthorship W2010145174A5045690666 @default.
- W2010145174 hasAuthorship W2010145174A5065911668 @default.
- W2010145174 hasAuthorship W2010145174A5073122096 @default.
- W2010145174 hasConcept C126322002 @default.
- W2010145174 hasConcept C142724271 @default.
- W2010145174 hasConcept C204787440 @default.
- W2010145174 hasConcept C2776164576 @default.
- W2010145174 hasConcept C2776268809 @default.
- W2010145174 hasConcept C2777077863 @default.
- W2010145174 hasConcept C2777288759 @default.
- W2010145174 hasConcept C2777575956 @default.
- W2010145174 hasConcept C2778163477 @default.
- W2010145174 hasConcept C2778484676 @default.
- W2010145174 hasConcept C2778697171 @default.
- W2010145174 hasConcept C2780026642 @default.
- W2010145174 hasConcept C2780035454 @default.
- W2010145174 hasConcept C71924100 @default.
- W2010145174 hasConcept C90924648 @default.
- W2010145174 hasConcept C98274493 @default.
- W2010145174 hasConceptScore W2010145174C126322002 @default.
- W2010145174 hasConceptScore W2010145174C142724271 @default.
- W2010145174 hasConceptScore W2010145174C204787440 @default.
- W2010145174 hasConceptScore W2010145174C2776164576 @default.
- W2010145174 hasConceptScore W2010145174C2776268809 @default.
- W2010145174 hasConceptScore W2010145174C2777077863 @default.
- W2010145174 hasConceptScore W2010145174C2777288759 @default.
- W2010145174 hasConceptScore W2010145174C2777575956 @default.
- W2010145174 hasConceptScore W2010145174C2778163477 @default.
- W2010145174 hasConceptScore W2010145174C2778484676 @default.
- W2010145174 hasConceptScore W2010145174C2778697171 @default.
- W2010145174 hasConceptScore W2010145174C2780026642 @default.
- W2010145174 hasConceptScore W2010145174C2780035454 @default.
- W2010145174 hasConceptScore W2010145174C71924100 @default.
- W2010145174 hasConceptScore W2010145174C90924648 @default.
- W2010145174 hasConceptScore W2010145174C98274493 @default.
- W2010145174 hasIssue "1" @default.
- W2010145174 hasLocation W20101451741 @default.
- W2010145174 hasLocation W20101451742 @default.
- W2010145174 hasOpenAccess W2010145174 @default.
- W2010145174 hasPrimaryLocation W20101451741 @default.
- W2010145174 hasRelatedWork W1978021271 @default.
- W2010145174 hasRelatedWork W2010145174 @default.
- W2010145174 hasRelatedWork W2048531807 @default.
- W2010145174 hasRelatedWork W2068097628 @default.
- W2010145174 hasRelatedWork W2396884853 @default.
- W2010145174 hasRelatedWork W2412861326 @default.
- W2010145174 hasRelatedWork W2616933475 @default.
- W2010145174 hasRelatedWork W2618751246 @default.
- W2010145174 hasRelatedWork W2994360215 @default.
- W2010145174 hasRelatedWork W2498516650 @default.
- W2010145174 hasVolume "36" @default.
- W2010145174 isParatext "false" @default.
- W2010145174 isRetracted "false" @default.
- W2010145174 magId "2010145174" @default.
- W2010145174 workType "article" @default.