FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010147661> ?p ?o ?g. }

• W2010147661 endingPage "34" @default.
• W2010147661 startingPage "29" @default.
• W2010147661 abstract "The ability of actin to both polymerize into filaments and to depolymerize permits the rapid rearrangements of actin structures that are essential for actin's function in most cellular processes. Filament polarity and dynamic properties are conferred by the hydrolysis of ATP on actin filaments. Release of inorganic phosphate (Pi) from filaments after ATP hydrolysis promotes depolymerization. We identify a yeast actin mutation, Val-159 to Asn, which uncouples Pi release from the conformational change that results in filament destabilization. Three-dimensional reconstructions of electron micrographs reveal a conformational difference between ADP-Pi filaments and ADP filaments and show that ADP V159N filaments resemble ADP-Pi wild-type filaments. Crystal structures of mammalian beta-actin in which the nucleotide binding cleft is in the open and closed states can be used to model actin filaments in the ADP and ADP-Pi conformations, respectively. We propose that these two conformations of G-actin may be related to two functional states of F-actin." @default.
• W2010147661 created "2016-06-24" @default.
• W2010147661 creator A5014879094 @default.
• W2010147661 creator A5054885812 @default.
• W2010147661 creator A5061998778 @default.
• W2010147661 creator A5074302940 @default.
• W2010147661 date "1999-01-05" @default.
• W2010147661 modified "2023-09-23" @default.
• W2010147661 title "A change in actin conformation associated with filament instability after P _i release" @default.
• W2010147661 cites W1539622248 @default.
• W2010147661 cites W1539711621 @default.
• W2010147661 cites W1562829155 @default.
• W2010147661 cites W1875421809 @default.
• W2010147661 cites W1921408963 @default.
• W2010147661 cites W1980668708 @default.
• W2010147661 cites W1984210761 @default.
• W2010147661 cites W1986239975 @default.
• W2010147661 cites W1988934709 @default.
• W2010147661 cites W1989939233 @default.
• W2010147661 cites W2009934656 @default.
• W2010147661 cites W2010590930 @default.
• W2010147661 cites W2016831365 @default.
• W2010147661 cites W2026064166 @default.
• W2010147661 cites W2033061682 @default.
• W2010147661 cites W2034943952 @default.
• W2010147661 cites W2035270427 @default.
• W2010147661 cites W2044583883 @default.
• W2010147661 cites W2045621376 @default.
• W2010147661 cites W2047409736 @default.
• W2010147661 cites W2048432059 @default.
• W2010147661 cites W2053373192 @default.
• W2010147661 cites W2057406301 @default.
• W2010147661 cites W2057971165 @default.
• W2010147661 cites W2060482091 @default.
• W2010147661 cites W2063796339 @default.
• W2010147661 cites W2076201930 @default.
• W2010147661 cites W2091062167 @default.
• W2010147661 cites W2101441813 @default.
• W2010147661 cites W2122782850 @default.
• W2010147661 cites W2140040046 @default.
• W2010147661 cites W2149828766 @default.
• W2010147661 cites W2175157633 @default.
• W2010147661 cites W2333112981 @default.
• W2010147661 cites W2410054405 @default.
• W2010147661 cites W4239924819 @default.
• W2010147661 cites W4249119784 @default.
• W2010147661 cites W4302419583 @default.
• W2010147661 doi "https://doi.org/10.1073/pnas.96.1.29" @default.
• W2010147661 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/15087" @default.
• W2010147661 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9874766" @default.
• W2010147661 hasPublicationYear "1999" @default.
• W2010147661 type Work @default.
• W2010147661 sameAs 2010147661 @default.
• W2010147661 citedByCount "156" @default.
• W2010147661 countsByYear W20101476612012 @default.
• W2010147661 countsByYear W20101476612013 @default.
• W2010147661 countsByYear W20101476612014 @default.
• W2010147661 countsByYear W20101476612015 @default.
• W2010147661 countsByYear W20101476612016 @default.
• W2010147661 countsByYear W20101476612017 @default.
• W2010147661 countsByYear W20101476612018 @default.
• W2010147661 countsByYear W20101476612019 @default.
• W2010147661 countsByYear W20101476612020 @default.
• W2010147661 countsByYear W20101476612021 @default.
• W2010147661 countsByYear W20101476612022 @default.
• W2010147661 crossrefType "journal-article" @default.
• W2010147661 hasAuthorship W2010147661A5014879094 @default.
• W2010147661 hasAuthorship W2010147661A5054885812 @default.
• W2010147661 hasAuthorship W2010147661A5061998778 @default.
• W2010147661 hasAuthorship W2010147661A5074302940 @default.
• W2010147661 hasBestOaLocation W20101476612 @default.
• W2010147661 hasConcept C12554922 @default.
• W2010147661 hasConcept C125705527 @default.
• W2010147661 hasConcept C130861313 @default.
• W2010147661 hasConcept C141315368 @default.
• W2010147661 hasConcept C14228908 @default.
• W2010147661 hasConcept C142669718 @default.
• W2010147661 hasConcept C1491633281 @default.
• W2010147661 hasConcept C178790620 @default.
• W2010147661 hasConcept C181199279 @default.
• W2010147661 hasConcept C185592680 @default.
• W2010147661 hasConcept C189040839 @default.
• W2010147661 hasConcept C205309164 @default.
• W2010147661 hasConcept C23265538 @default.
• W2010147661 hasConcept C2993400109 @default.
• W2010147661 hasConcept C3620293 @default.
• W2010147661 hasConcept C49852136 @default.
• W2010147661 hasConcept C53009064 @default.
• W2010147661 hasConcept C55493867 @default.
• W2010147661 hasConcept C8010536 @default.
• W2010147661 hasConcept C86803240 @default.
• W2010147661 hasConceptScore W2010147661C12554922 @default.
• W2010147661 hasConceptScore W2010147661C125705527 @default.
• W2010147661 hasConceptScore W2010147661C130861313 @default.
• W2010147661 hasConceptScore W2010147661C141315368 @default.
• W2010147661 hasConceptScore W2010147661C14228908 @default.
• W2010147661 hasConceptScore W2010147661C142669718 @default.
• W2010147661 hasConceptScore W2010147661C1491633281 @default.

• next