Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010147952> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2010147952 endingPage "S178" @default.
- W2010147952 startingPage "S172" @default.
- W2010147952 abstract "We examined the effect of sofalcone, a mucosal protective agent that has been reported to inhibit growth of Helicobacter pylori, on adherence, production of vacuolating toxin (VT), and induction of interleukin-8(IL-8) secretion by H. pylori. Mixing VT with various concentrations(1.5-100 μg/ml) of sofalcone resulted in a 50% decrease in the VT titer. When toxigenic H. pylori strains were incubated in the presence of sofalcone(20 and 40 μg/ml), although bacterial growth was not inhibited significantly there was significant inhibition of VT production. Notable inhibition of IL-8 secretion by human gastric cancer cells (MKN 45) was detected in the presence of sofalcone(20-100 μg/ml) after co-incubation with H. pylori strains. In flow cytometric analysis, adherence of H. pylori strains to MKN 45 cells was significantly inhibited by treatment with sofalcone (20-60 μg/ml), indicating at least one reason for the inhibition of IL-8 secretion. These results show that sofalcone is an effective mucosal protective agent that inhibits both production of VT and induction of IL-8 secretion." @default.
- W2010147952 created "2016-06-24" @default.
- W2010147952 creator A5022951745 @default.
- W2010147952 creator A5028816095 @default.
- W2010147952 creator A5048640463 @default.
- W2010147952 creator A5056381274 @default.
- W2010147952 creator A5084403788 @default.
- W2010147952 date "1997-01-01" @default.
- W2010147952 modified "2023-09-24" @default.
- W2010147952 title "Effect of Sofalcone on Adherence, Production of Vacuolating Toxin, and Induction of Interleukin-8 Secretion by Helicobacter pylori" @default.
- W2010147952 cites W1538891740 @default.
- W2010147952 cites W1561069887 @default.
- W2010147952 cites W1855959757 @default.
- W2010147952 cites W2010459522 @default.
- W2010147952 cites W2019542686 @default.
- W2010147952 cites W2022610619 @default.
- W2010147952 cites W2027770415 @default.
- W2010147952 cites W2041831466 @default.
- W2010147952 cites W2054247187 @default.
- W2010147952 cites W2068656612 @default.
- W2010147952 cites W2086658308 @default.
- W2010147952 cites W2103264839 @default.
- W2010147952 cites W2108467352 @default.
- W2010147952 cites W2132293085 @default.
- W2010147952 cites W2135327044 @default.
- W2010147952 cites W2135972635 @default.
- W2010147952 cites W2147048960 @default.
- W2010147952 cites W2169073794 @default.
- W2010147952 cites W2170903620 @default.
- W2010147952 cites W2179512298 @default.
- W2010147952 cites W2319055537 @default.
- W2010147952 cites W2321415533 @default.
- W2010147952 doi "https://doi.org/10.1097/00004836-199700001-00028" @default.
- W2010147952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9479645" @default.
- W2010147952 hasPublicationYear "1997" @default.
- W2010147952 type Work @default.
- W2010147952 sameAs 2010147952 @default.
- W2010147952 citedByCount "7" @default.
- W2010147952 countsByYear W20101479522014 @default.
- W2010147952 countsByYear W20101479522019 @default.
- W2010147952 crossrefType "journal-article" @default.
- W2010147952 hasAuthorship W2010147952A5022951745 @default.
- W2010147952 hasAuthorship W2010147952A5028816095 @default.
- W2010147952 hasAuthorship W2010147952A5048640463 @default.
- W2010147952 hasAuthorship W2010147952A5056381274 @default.
- W2010147952 hasAuthorship W2010147952A5084403788 @default.
- W2010147952 hasConcept C126322002 @default.
- W2010147952 hasConcept C159654299 @default.
- W2010147952 hasConcept C202751555 @default.
- W2010147952 hasConcept C203014093 @default.
- W2010147952 hasConcept C25642318 @default.
- W2010147952 hasConcept C2776409635 @default.
- W2010147952 hasConcept C2777367657 @default.
- W2010147952 hasConcept C2778690821 @default.
- W2010147952 hasConcept C2779707156 @default.
- W2010147952 hasConcept C32611913 @default.
- W2010147952 hasConcept C49039625 @default.
- W2010147952 hasConcept C55493867 @default.
- W2010147952 hasConcept C71924100 @default.
- W2010147952 hasConcept C74172505 @default.
- W2010147952 hasConcept C86803240 @default.
- W2010147952 hasConcept C89423630 @default.
- W2010147952 hasConceptScore W2010147952C126322002 @default.
- W2010147952 hasConceptScore W2010147952C159654299 @default.
- W2010147952 hasConceptScore W2010147952C202751555 @default.
- W2010147952 hasConceptScore W2010147952C203014093 @default.
- W2010147952 hasConceptScore W2010147952C25642318 @default.
- W2010147952 hasConceptScore W2010147952C2776409635 @default.
- W2010147952 hasConceptScore W2010147952C2777367657 @default.
- W2010147952 hasConceptScore W2010147952C2778690821 @default.
- W2010147952 hasConceptScore W2010147952C2779707156 @default.
- W2010147952 hasConceptScore W2010147952C32611913 @default.
- W2010147952 hasConceptScore W2010147952C49039625 @default.
- W2010147952 hasConceptScore W2010147952C55493867 @default.
- W2010147952 hasConceptScore W2010147952C71924100 @default.
- W2010147952 hasConceptScore W2010147952C74172505 @default.
- W2010147952 hasConceptScore W2010147952C86803240 @default.
- W2010147952 hasConceptScore W2010147952C89423630 @default.
- W2010147952 hasLocation W20101479521 @default.
- W2010147952 hasLocation W20101479522 @default.
- W2010147952 hasOpenAccess W2010147952 @default.
- W2010147952 hasPrimaryLocation W20101479521 @default.
- W2010147952 hasRelatedWork W1487341457 @default.
- W2010147952 hasRelatedWork W1493326298 @default.
- W2010147952 hasRelatedWork W2002214933 @default.
- W2010147952 hasRelatedWork W2010147952 @default.
- W2010147952 hasRelatedWork W2108221712 @default.
- W2010147952 hasRelatedWork W2163923351 @default.
- W2010147952 hasRelatedWork W2287677316 @default.
- W2010147952 hasRelatedWork W2397173935 @default.
- W2010147952 hasRelatedWork W2485715100 @default.
- W2010147952 hasRelatedWork W2067403872 @default.
- W2010147952 hasVolume "25" @default.
- W2010147952 isParatext "false" @default.
- W2010147952 isRetracted "false" @default.
- W2010147952 magId "2010147952" @default.
- W2010147952 workType "article" @default.