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- W2010149410 abstract "A series of 3-substituted-1(3H)-isobenzofuranone 6a-g and 7a-g were synthesized from phthalic anhydride. The compound 6a-g was resolved. The antiplatelet activities of these compounds were evaluated using in vitro experiment of platelet aggregation. The levels of antiplatelet activity were displayed as following sequence: l-isomer >dl-isomer>d-isomer, respectively. The alkylphthalide is more active than the corresponding alkenephthalide. All these compounds were less active than n-butylphthalide (NBP, 6c) and Aspirin (Asp)." @default.
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- W2010149410 date "2007-09-01" @default.
- W2010149410 modified "2023-10-14" @default.
- W2010149410 title "Synthesis, resolution, and antiplatelet activity of 3-substituted 1(3H)-isobenzofuranone" @default.
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- W2010149410 doi "https://doi.org/10.1016/j.bmcl.2007.06.082" @default.
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