FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010161331> ?p ?o ?g. }

• W2010161331 endingPage "107" @default.
• W2010161331 startingPage "99" @default.
• W2010161331 abstract "The class III POU proteins are expressed throughout the central nervous system, including the hypothalamus, where they are often co-localized. Presumably, these POU proteins (Brain-1, Brain-2, Brain-4 and SCIP) serve as transcriptional transactivators. That they are co-expressed in some neurons suggests that, if they were to form homomeric and heteromeric complexes with each other, depending on the particular combination, they might have different DNA-binding specificities and, thus, activate different genes. We used purified fusion proteins of the four class III POU proteins in far-western assays to show that the proteins can interact. We confirmed their interactions using a two-hybrid system. Both techniques indicate that the interaction occurs through the POU domain. The far-western technique also allowed us to identify a 120-kDa nuclear protein that interacts with Brain-4. Subsequent affinity purification and microsequencing identified the protein as the heterogeneous nuclear ribonucleoprotein U (hnRNP U). This result suggests another mechanism by which a POU protein can influence gene expression: by facilitating the processing of pre-mRNA whose transcription it has stimulated." @default.
• W2010161331 created "2016-06-24" @default.
• W2010161331 creator A5050599388 @default.
• W2010161331 creator A5067967619 @default.
• W2010161331 creator A5080278598 @default.
• W2010161331 creator A5084090331 @default.
• W2010161331 date "1997-04-01" @default.
• W2010161331 modified "2023-09-23" @default.
• W2010161331 title "The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U" @default.
• W2010161331 cites W1589532501 @default.
• W2010161331 cites W1965467790 @default.
• W2010161331 cites W1970132032 @default.
• W2010161331 cites W1979647722 @default.
• W2010161331 cites W1990097058 @default.
• W2010161331 cites W1991195894 @default.
• W2010161331 cites W1993243592 @default.
• W2010161331 cites W2016493017 @default.
• W2010161331 cites W2025903960 @default.
• W2010161331 cites W2029117845 @default.
• W2010161331 cites W2030731742 @default.
• W2010161331 cites W2031605069 @default.
• W2010161331 cites W2054968530 @default.
• W2010161331 cites W2068925449 @default.
• W2010161331 cites W2075157322 @default.
• W2010161331 cites W2077718247 @default.
• W2010161331 cites W2085430625 @default.
• W2010161331 cites W2092692873 @default.
• W2010161331 cites W2093897768 @default.
• W2010161331 cites W2101679570 @default.
• W2010161331 cites W2137433289 @default.
• W2010161331 cites W2153017169 @default.
• W2010161331 cites W2167974691 @default.
• W2010161331 cites W2253798784 @default.
• W2010161331 doi "https://doi.org/10.1016/s0169-328x(96)00238-0" @default.
• W2010161331 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9105675" @default.
• W2010161331 hasPublicationYear "1997" @default.
• W2010161331 type Work @default.
• W2010161331 sameAs 2010161331 @default.
• W2010161331 citedByCount "19" @default.
• W2010161331 countsByYear W20101613312012 @default.
• W2010161331 countsByYear W20101613312013 @default.
• W2010161331 countsByYear W20101613312014 @default.
• W2010161331 countsByYear W20101613312015 @default.
• W2010161331 countsByYear W20101613312016 @default.
• W2010161331 countsByYear W20101613312023 @default.
• W2010161331 crossrefType "journal-article" @default.
• W2010161331 hasAuthorship W2010161331A5050599388 @default.
• W2010161331 hasAuthorship W2010161331A5067967619 @default.
• W2010161331 hasAuthorship W2010161331A5080278598 @default.
• W2010161331 hasAuthorship W2010161331A5084090331 @default.
• W2010161331 hasBestOaLocation W20101613312 @default.
• W2010161331 hasConcept C104317684 @default.
• W2010161331 hasConcept C121587040 @default.
• W2010161331 hasConcept C123894998 @default.
• W2010161331 hasConcept C153911025 @default.
• W2010161331 hasConcept C196287685 @default.
• W2010161331 hasConcept C2909472194 @default.
• W2010161331 hasConcept C29512474 @default.
• W2010161331 hasConcept C40767141 @default.
• W2010161331 hasConcept C54355233 @default.
• W2010161331 hasConcept C67705224 @default.
• W2010161331 hasConcept C75934600 @default.
• W2010161331 hasConcept C86339819 @default.
• W2010161331 hasConcept C86803240 @default.
• W2010161331 hasConcept C94966510 @default.
• W2010161331 hasConcept C95444343 @default.
• W2010161331 hasConceptScore W2010161331C104317684 @default.
• W2010161331 hasConceptScore W2010161331C121587040 @default.
• W2010161331 hasConceptScore W2010161331C123894998 @default.
• W2010161331 hasConceptScore W2010161331C153911025 @default.
• W2010161331 hasConceptScore W2010161331C196287685 @default.
• W2010161331 hasConceptScore W2010161331C2909472194 @default.
• W2010161331 hasConceptScore W2010161331C29512474 @default.
• W2010161331 hasConceptScore W2010161331C40767141 @default.
• W2010161331 hasConceptScore W2010161331C54355233 @default.
• W2010161331 hasConceptScore W2010161331C67705224 @default.
• W2010161331 hasConceptScore W2010161331C75934600 @default.
• W2010161331 hasConceptScore W2010161331C86339819 @default.
• W2010161331 hasConceptScore W2010161331C86803240 @default.
• W2010161331 hasConceptScore W2010161331C94966510 @default.
• W2010161331 hasConceptScore W2010161331C95444343 @default.
• W2010161331 hasIssue "1" @default.
• W2010161331 hasLocation W20101613311 @default.
• W2010161331 hasLocation W20101613312 @default.
• W2010161331 hasLocation W20101613313 @default.
• W2010161331 hasOpenAccess W2010161331 @default.
• W2010161331 hasPrimaryLocation W20101613311 @default.
• W2010161331 hasRelatedWork W2004712987 @default.
• W2010161331 hasRelatedWork W2010161331 @default.
• W2010161331 hasRelatedWork W2094922317 @default.
• W2010161331 hasRelatedWork W2149899899 @default.
• W2010161331 hasRelatedWork W2150093511 @default.
• W2010161331 hasRelatedWork W2164263837 @default.
• W2010161331 hasRelatedWork W2975974060 @default.
• W2010161331 hasRelatedWork W3081986552 @default.
• W2010161331 hasRelatedWork W3161120950 @default.
• W2010161331 hasRelatedWork W4251527342 @default.
• W2010161331 hasVolume "45" @default.

• next