Matches in SemOpenAlex for { <https://semopenalex.org/work/W2010200713> ?p ?o ?g. }
- W2010200713 endingPage "815" @default.
- W2010200713 startingPage "807" @default.
- W2010200713 abstract "Little is known about the molecular features of desmoplastic infantile ganglioglioma (DIG) and desmoplastic infantile astrocytoma (DIA). We performed a genome-wide DNA copy number analysis in combination with a multiplex ligation-dependent probe amplification-based analysis of copy number changes of candidate genes in 4 DIAs and 10 DIGs. Molecular inversion probe (MIP) assay showed that large chromosomal alterations were rare among DIG and DIA. Focal recurrent genomic losses were observed in chromosome regions such as 5q13.3, 21q22.11, and 10q21.3 in both DIA and DIG. Principal component analysis did not show any significant differences between the molecular profiles of DIG and DIA, and a hierarchical cluster analysis did not clearly separate the 2 tumor groups according to their molecular profiles. In 6 cases, gain of genomic material at 7q31 (corresponding to MET gene) was found in multiplex ligation-dependent probe amplification (MLPA) analysis. Furthermore, two cases showed gain at 4q12, and a single case showed BRAF mutation. In agreement with previous analyses, this study demonstrates the absence of consistent recurrent chromosomal alterations in DIA and DIG and overall rarity of the BRAF mutation in these tumors. Notably, these results suggest that DIA and DIG represent a histologic spectrum of the same tumor rather than 2 separate entities." @default.
- W2010200713 created "2016-06-24" @default.
- W2010200713 creator A5046361912 @default.
- W2010200713 creator A5050894746 @default.
- W2010200713 creator A5053095305 @default.
- W2010200713 creator A5053770173 @default.
- W2010200713 creator A5064379777 @default.
- W2010200713 creator A5077551181 @default.
- W2010200713 date "2013-09-01" @default.
- W2010200713 modified "2023-10-17" @default.
- W2010200713 title "Genome-Wide DNA Copy Number Analysis of Desmoplastic Infantile Astrocytomas and Desmoplastic Infantile Gangliogliomas" @default.
- W2010200713 cites W1695184746 @default.
- W2010200713 cites W1930097530 @default.
- W2010200713 cites W1985681518 @default.
- W2010200713 cites W1985714842 @default.
- W2010200713 cites W1996288295 @default.
- W2010200713 cites W1999166815 @default.
- W2010200713 cites W2001061723 @default.
- W2010200713 cites W2010760434 @default.
- W2010200713 cites W2020365342 @default.
- W2010200713 cites W2038305873 @default.
- W2010200713 cites W2043709310 @default.
- W2010200713 cites W2069761182 @default.
- W2010200713 cites W2075329769 @default.
- W2010200713 cites W2083007177 @default.
- W2010200713 cites W2089678016 @default.
- W2010200713 cites W2113193726 @default.
- W2010200713 cites W2116063037 @default.
- W2010200713 cites W2124664680 @default.
- W2010200713 cites W2129574601 @default.
- W2010200713 cites W2146267855 @default.
- W2010200713 cites W2151311897 @default.
- W2010200713 cites W2160405811 @default.
- W2010200713 cites W2168640478 @default.
- W2010200713 cites W2313938789 @default.
- W2010200713 cites W2335272795 @default.
- W2010200713 doi "https://doi.org/10.1097/nen.0b013e3182a033a0" @default.
- W2010200713 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23965740" @default.
- W2010200713 hasPublicationYear "2013" @default.
- W2010200713 type Work @default.
- W2010200713 sameAs 2010200713 @default.
- W2010200713 citedByCount "32" @default.
- W2010200713 countsByYear W20102007132014 @default.
- W2010200713 countsByYear W20102007132015 @default.
- W2010200713 countsByYear W20102007132016 @default.
- W2010200713 countsByYear W20102007132017 @default.
- W2010200713 countsByYear W20102007132018 @default.
- W2010200713 countsByYear W20102007132019 @default.
- W2010200713 countsByYear W20102007132021 @default.
- W2010200713 countsByYear W20102007132022 @default.
- W2010200713 countsByYear W20102007132023 @default.
- W2010200713 crossrefType "journal-article" @default.
- W2010200713 hasAuthorship W2010200713A5046361912 @default.
- W2010200713 hasAuthorship W2010200713A5050894746 @default.
- W2010200713 hasAuthorship W2010200713A5053095305 @default.
- W2010200713 hasAuthorship W2010200713A5053770173 @default.
- W2010200713 hasAuthorship W2010200713A5064379777 @default.
- W2010200713 hasAuthorship W2010200713A5077551181 @default.
- W2010200713 hasBestOaLocation W20102007131 @default.
- W2010200713 hasConcept C104317684 @default.
- W2010200713 hasConcept C120599132 @default.
- W2010200713 hasConcept C120821319 @default.
- W2010200713 hasConcept C124942203 @default.
- W2010200713 hasConcept C141231307 @default.
- W2010200713 hasConcept C153911025 @default.
- W2010200713 hasConcept C16654397 @default.
- W2010200713 hasConcept C2778227246 @default.
- W2010200713 hasConcept C2778880634 @default.
- W2010200713 hasConcept C2781188995 @default.
- W2010200713 hasConcept C30481170 @default.
- W2010200713 hasConcept C36823959 @default.
- W2010200713 hasConcept C54355233 @default.
- W2010200713 hasConcept C86803240 @default.
- W2010200713 hasConceptScore W2010200713C104317684 @default.
- W2010200713 hasConceptScore W2010200713C120599132 @default.
- W2010200713 hasConceptScore W2010200713C120821319 @default.
- W2010200713 hasConceptScore W2010200713C124942203 @default.
- W2010200713 hasConceptScore W2010200713C141231307 @default.
- W2010200713 hasConceptScore W2010200713C153911025 @default.
- W2010200713 hasConceptScore W2010200713C16654397 @default.
- W2010200713 hasConceptScore W2010200713C2778227246 @default.
- W2010200713 hasConceptScore W2010200713C2778880634 @default.
- W2010200713 hasConceptScore W2010200713C2781188995 @default.
- W2010200713 hasConceptScore W2010200713C30481170 @default.
- W2010200713 hasConceptScore W2010200713C36823959 @default.
- W2010200713 hasConceptScore W2010200713C54355233 @default.
- W2010200713 hasConceptScore W2010200713C86803240 @default.
- W2010200713 hasIssue "9" @default.
- W2010200713 hasLocation W20102007131 @default.
- W2010200713 hasLocation W20102007132 @default.
- W2010200713 hasOpenAccess W2010200713 @default.
- W2010200713 hasPrimaryLocation W20102007131 @default.
- W2010200713 hasRelatedWork W1981217509 @default.
- W2010200713 hasRelatedWork W2010200713 @default.
- W2010200713 hasRelatedWork W2013551284 @default.
- W2010200713 hasRelatedWork W2089607987 @default.
- W2010200713 hasRelatedWork W2141432779 @default.
- W2010200713 hasRelatedWork W2272828706 @default.