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• W2010204828 abstract "Dendritic cells have been known as a member of strong innate immune cells against infectious organelles. In this study, we evaluated the cytokine expression of splenic dendritic cells in chronic mouse toxoplasmosis by tissue cyst-forming Me49 strain and demonstrated the distribution of lymphoid dendritic cells by fluorescence-activated cell sorter (FACS). Pro-inflammatory cytokines, such as IL-1α, IL-1β, IL-6, and IL-10 increased rapidly at week 1 post-infection (PI) and peaked at week 3 PI. Serum IL-10 level followed the similar patterns. FACS analysis showed that the number of CD8α(+)/CD11c(+) splenic dendritic cells increased at week 1 and peaked at week 3 PI. In conclusion, mouse splenic dendritic cells showed early and rapid cytokine changes and may have important protective roles in early phases of murine toxoplasmosis." @default.
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• W2010204828 date "2011-01-01" @default.
• W2010204828 modified "2023-10-16" @default.
• W2010204828 title "Pro-inflammatory Cytokine Expression of Spleen Dendritic Cells in Mouse Toxoplasmosis" @default.
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• W2010204828 doi "https://doi.org/10.3347/kjp.2011.49.2.109" @default.
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